HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E4814 Teneligliptin Hydrobromide Hydrate Teneligliptin Hydrobromide Hydrate(MP-513 hydrobromide hydrate) is a potent, competitive, and long-lasting inhibitor of DPP-4. It competitively inhibited rhDPP-4, human plasma, and rat plasma with IC50 values of 0.889, 1.75, and 1.35 nM respectively. It suppresses high glucose-mediated mitochondrial dysfunction and can be used for treatment of type 2 diabetes. Oct 17 2024
E1982 SOP1812 SOP1812( QN-302), is a tetra-substituted naphthalene diimide (ND) derivative and selective inhibitor of G-quadruplex (G4) transcription. It shows great affinity to hTERT G4 and HuTel21 G4 with KD values of 4.9 and 28.4 nM, respectively. It binds to G-quadruplex DNA in cancer gene promoters region and shows strong anti-proliferative and anti-tumor activity in pancreatic cancer models. Oct 17 2024
E4709 MS-L6 MS-L6(Agn-PC-0N3ahi, NSC34338) is a potent inhibitor of OXPHOS, targeting electron transport chain complexes I (ETC-I), combining inhibition of NADH oxidation and uncoupling effect, on the respiratory chain. It exhibits potent antitumor efficacy. Oct 17 2024
E4628 BMS-986235 BMS-986235 (LAR-1219) is a selective, orally active and potent agonist of formyl peptide receptor 2 (FPR2), with EC50 values of 0.41 nM and 3.4 nM for hFPR2 and mFPR2, respectively. BMS-986235 therapy shows promising improvements in cardiac structure and function in a mouse model of heart failure, highlighting its potential for preventing the progression of heart failure. Oct 15 2024
E4703 Culmerciclib Culmerciclib (TQB3616) is a potent inhibitor of cyclin dependent kinase (CDK)4/6 and exhibits highly effective antineoplastic activity. TQB3616 exhibits significant synergistic antitumor activity in estrogen receptor (ER)-positive/HER2-negative or HER2-positive breast cancer when combined with endocrine therapy or Human Epidermal Growth Factor Receptor 2 (HER2) targeted therapy. Oct 15 2024
E4704 D34-919 D34-919 is potent inhibitor of the ALDH1A3-PKM2 interaction, and prevents the ALDH1A3-mediated enhancement of PKM2 tetramerization. D34-919 mediated in vitro and in vivo treatment enhances and restores chemoradiotherapy-induced apoptosis and sensitivity in glioblastoma (GBM) cells. Oct 15 2024
E1288 Inaxaplin Inaxaplin (VX-147) is an orally active inhibitor of apolipoprotein L1 (APOL1) function. Inaxaplin binds to APOL1 and is useful in the treatment of APOL1-associated kidney disease. Oct 15 2024
E4936 Larazotide acetate Larazotide acetate(AT-1001), a synthetic peptide, is an antagonist of zonulin. It functions as a gut permeability regulator for the treatment of celiac disease.  Oct 15 2024
E1633 BAY-805 BAY-805 is a potent, selective, and cell-active inhibitor that non-covalently targets the catalytic activity of USP21, a member of the ubiquitin-specific protease (USP) subfamily of deubiquitinating enzymes (DUBs). Oct 15 2024
A2165 Anti-mouse PD-1 (CD279)(29F.1A12)-InVivo Anti-mouse PD-1 (CD279)(29F.1A12)-InVivo reacts with mouse PD-1 (programmed death-1) also known as CD279. PD-1 is a 50-55 kDa cell surface receptor encoded by the Pdcd1 gene that belongs to the CD28 family of the Ig superfamily. Oct 12 2024
E4945 Pregnenolone monosulfate sodium Pregnenolone monosulfate sodium, a sodium salt form of pregnenolone monosulfate, is an active neurosteroid and a precursor of all steroid hormones. It functions act as a potent endogenous allosteric signal-specific inhibitor of CB1 receptors, reducing psychoactive effects associated with Δ9-tetrahydrocannabinol (THC). Oct 10 2024
E4652 ZX703 ZX703 is a proteolysis targeting chimera (PROTAC), that is a degrader of GPX4 through the ubiquitin-proteasome and the autophagy-lysosome with a DC50 of 0.315 µM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby inducing ferroptosis cancer cells. Oct 10 2024
E1301 Imlunestrant Imlunestrant(LY3484356) is a potent, orally bioavailable selective estrogen receptor degrader (SERD) that functions as a pure antagonist of estrogen receptor alpha (ERα). It inhibits ER-dependent gene transcription and cell proliferation, resulting in sustained suppression of estrogen-driven growth in ER-positive cells. Oct 10 2024
E4715 SB-328437 SB-328437 is a non-peptide small molecule, potent and selective antagonist of CCR3 with an IC50 of 4.5 nM. It is important for eosinophil recruitment, a process that is thought to be crucial in the pathology of several inflammatory diseases including asthma, allergic rhinitis, and eczema. Oct 10 2024
F1715 pro Caspase3 Rabbit mAb Oct 09 2024
F2311 Neuron-specific β-III Tubulin mAb beta III Tubulin,beta-3 Tubulin,beta-III Tubulin,beta-Tubulin III,beta-Tubulin III (neuronal),beta-Tubulin Isotype III,Tubulin beta III,Tubulin betaIII,β3 Tubulin,β3-Tubulin Oct 09 2024
F2365 Arp3 C-terminal Rabbit mAb Oct 09 2024
F2408 ARL 13B mAb Oct 09 2024
F2431 Cytokeratin 16/K16 Rabbit mAb Oct 09 2024
F2434 Fragilis Rabbit mAb Fragilis,IFITM3 Oct 09 2024