All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E7149 Nitrilotriacetic acid Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions. Dec 19 2024
E7373 Ketone monoester Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes. Dec 19 2024
E7150 Tirbanibulin dihydrochloride Tirbanibulin (dihydrochloride) (KX2-391 (dihydrochloride)) is an inhibitor of Src that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines. Dec 19 2024
E7151 Mephenytoin Mephenytoin, an anticonvulsant, is the CYP2C19 and CYP2B6 substrate. Dec 19 2024
E7375 Phenanthrene Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment. Dec 19 2024
E7152 Neurotensin(8-13) Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. Dec 19 2024
E7376 Fluorene Fluorene, a polycyclic aromatic hydrocarbon (PAH), is a precursor to other fluorene compounds. Fluorene and its derivative can be used as a precursor to fluorene-based dyes. Dec 19 2024
E7153 C2 Ceramide C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis, inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss. Dec 19 2024
E7154 C16-Ceramide C16-Ceramide (N-Palmitoylsphingosine)is a sphingolipid ligand and an activator of p53 tumor suppressor. It tightly binds within the p53 DNA-binding domain with a Kd of ~ 60 nM, in close vicinity to the Box V motif. It regulates the protein ubiquitination and proteasomal degradation and also induces apoptosis in cancer cells making it a research tool for targeting human cancers. Dec 19 2024
E7378 Chrysene Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties. Dec 19 2024
E7155 Prolylleucine Prolylleucine is a dipeptide containing branched-chain amino acids. Prolylleucine can affect the circadian rhythms and behaviour of animals. Dec 19 2024
E5720 Isocurcumenol Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1μg/mL and 178.2 μg/mL in DLA and KB cells, respectively. Dec 19 2024
E7156 CE3F4 CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively. Dec 19 2024
E7157 FSLLRY-NH2 FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor. Dec 19 2024
E7380 Pafuramidine Pafuramidine (DB289) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria. Dec 19 2024
E7158 Brilliant Blue FCF Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm. Dec 19 2024
E7381 Collagenase, Type I Collagenase, Type I is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type I breaks down collagens 1, 3, 7, 8, 10, gelatin, proteoglycans, aggrecan. Dec 19 2024
E5071 3-Acetyl-beta-boswellic acid 3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin. Dec 19 2024
E7159 Remdesivir O-desphosphate acetonide impurity Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro. Dec 19 2024
E7382 5-Methoxy-DL-tryptophan 5-Methoxy-DL-tryptophan is an endogenous metabolite. Dec 19 2024