HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E4891 Fostemsavir Tris Fostemsavir Tris(BMS-663068 Tris) is a phosphonooxymethyl prodrug of BMS-626529, formulated as a tris(hydroxymethyl)aminomethane salt. It inhibits human immunodeficiency virus type 1 (HIV-1) by binding to the gp120 protein, preventing the virus from attaching to CD4+ T-cells. Sep 12 2024
E4910 Cariprazine Cariprazine(RGH-188, MP-214) acts primarily as a partial agonist at dopamine receptors, with pKi values of 10.07 for D3, 9.16 for D2L, and 9.31 for D2S receptors. It also acts as an antagonist forserotonin receptors, with pKi of 9.24, 8.59, 7.73, and 6.87 for5-HT2B,5-HT1A, 5-HT2A, and 5-HT2C receptors, respectively. Sep 12 2024
E4929 (S)-Clopidogrel (S)-Clopidogrel is an inhibitor of P2Y12 and exerts anticoagulant effects. It is metabolized into an active form that binds to the P2Y12 receptor, blocking ADP and preventing platelet aggregation. It also exhibits anti-inflammatory and antifibrotic properties in chronic kidney disease (CKD) and liver fibrosis. Sep 12 2024
E4897 Estramustine Estramustine(NSC-89201, LEO275) is used to treat hormone-resistant prostate cancer and stabilize microtubule dynamics. It acts as an anti-mitotic and anti-microtubule agent and disrupts microtubule disassembly. It inhibits the binding of MAPs 1 and 2 to taxol-stabilized microtubules, hinders microtubule assembly, and promotes the disassembly of MAP-2-associated microtubules. Sep 12 2024
E4920 Baclofen hydrochloride Baclofen hydrochloride is an agonist of the GABAB receptor that mimics the action of GABA, leading to slow presynaptic inhibition via the GABAB receptor. It improves the function of the ubiquitin-proteasome system (UPS) and enhances cell survival in both in vitro and in vivo models of Huntington's disease (HD). Sep 12 2024
E4961 Rutin (trihydrate) Rutin trihydrate is a bioflavonoid composed of the flavonol quercetin and the disaccharide rutinose. It exhibits anti-inflammatory and antiproliferative properties. It also acts as an antioxidant by scavenging reactive oxygen species (ROS). It lowers ROS levels, which in turn reduces oxidative stress in neurons, thereby controlling neuropathy (including auditory neuropathy) in patients with diabetes. Sep 12 2024
F2091 Fascin Rabbit mAb Sep 12 2024
F2176 SUN2 Rabbit mAb Sep 12 2024
F2188 Cytokeratin 13 Rabbit mAb Sep 12 2024
F2203 CD47 Rabbit mAb CD47 Sep 12 2024
F2220 Phospho-Rb (Ser 807) Rabbit mAb Sep 12 2024
F2226 α smooth muscle Actin (acetyl Glu 3) + Actin γ2 (acetyl Glu3) Rabbit mAb Sep 12 2024
F2228 Glutamine Synthetase Rabbit mAb Gl Syn,Glutamine Synthetase Sep 12 2024
F2233 hnRNP C1 + C2/HNRNPC Rabbit mAb hnRNP C1 + C2/HNRNPC,hnRNP C1/C2 Sep 12 2024
F2355 MFF Rabbit mAb Sep 12 2024
F2417 RPS10 Rabbit mAb Sep 12 2024
F2418 FLI1 Rabbit mAb Sep 12 2024
F2420 CD166 Rabbit mAb CD166,CD166 (ALCAM) Sep 12 2024
F2634 RARγ1 Rabbit mAb Sep 12 2024
F2647 STAG2 Rabbit mAb SA2,SA-2,STAG2 Sep 12 2024