HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E1626 BMS-509744 BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM. Dec 26 2024
E6039 Imiquimod hydrochloride Imiquimod hydrochloride (R 837 hydrochloride) is a small-molecule immune response modifier, a potent and selective agonist of toll like receptor 7 (TLR7), an antagonist of adenosine A₂A receptor with a Ki of 2.16 μM, and an inhibitor of adenylyl cyclase activity, inducing antiviral proteins like cystatin A. It exhibits strong antitumoral and antiviral efficacy, making it effective for conditions such as COVID 19, HPV warts, molluscum contagiosum, actinic keratosis, basal and squamous cell carcinoma, Bowen's disease, and vulvar intraepithelial neoplasia. Dec 26 2024
E5807 Eflornithine Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Dec 26 2024
E4707 Aldosterone Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level. Dec 26 2024
E4743 NITD008 NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Dec 26 2024
E8146 Citric acid trisodium Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice. Dec 26 2024
E8147 PI-103 Hydrochloride PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy. Dec 26 2024
E8148 BAPTA BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. Dec 26 2024
E8149 Bovine Serum Albumin Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications. Dec 26 2024
E8150 Amiloride Amiloride (MK-870) is the first potent inhibitor of epithelial sodium channel (ENaC), inhibiting δβγ ENaC with an IC50 of 2.6 μM. It is also a typical blocker of PC2(TRPP2) channels and can be used in the research to study Autosomal dominant polycystic kidney disease (ADPKD). Dec 26 2024
E8152 Bay 41-4109 BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM. Dec 26 2024
E8153 Filipin complex Filipin complex is a potent polyene macrolide antifungal antibiotic that integrates into membranes, sequestering cholesterol into complexes. Its treatment reduces PRRSV genome copies by 61% and lowers the PRRSV titer. It also acts as a fluorescent histochemical stain prone to autooxidation, commonly used in diagnosing Niemann-Pick Disease Type C (NP-C), a neurodegenerative lysosomal storage disorder. Researchers also employ it to study unesterified cholesterol distribution in cell and animal models of neurodegenerative diseases like NP-C and Sanfilippo syndrome (MPS IIIA). Dec 26 2024
E8155 α-MSH α-MSH (α-Melanocyte-Stimulating Hormone) is an endogenous neuropeptide and an agonist melanocortin-4 receptor (MC4R). It demonstrates anti-inflammatory, antipyretic activities, staphylocidal activity and also exhibits strong and rapid antimicrobial activity. Dec 26 2024
E8156 2’3’-c-di-AM(PS)2 (Rp,Rp) (ammonium salt) 2’3’-c-di-AM(PS)2 (Rp,Rp) ammonium salt (ADU-S100 ammonium salt), an activator of stimulator of interferon genes (STING), leads to potent and systemic tumor regression and immunity. Dec 26 2024
E8157 FLAG peptide DYKDDDDK peptide is an eight-amino-acid (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys) epitope tag used for protein purification and detection. It enables antibody-mediated purification via affinity chromatography, Western blot, and immunoprecipitation. The hydrophilic and immunogenic tag can be fused to either the N- or C-terminus of proteins. Dec 26 2024
E8158 OTSSP167 hydrochloride OTSSP167 (OTS167) hydrochloride is a highly potent and ATP-competitive MELK inhibitor with IC50 value of 0.41 nM. Dec 26 2024
E8159 CY5-SE Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670. Dec 26 2024
E8160 Cyclo(-RGDfK) Cyclo(-RGDfK) is a cyclic peptides and a highly effective and selective Integrin αvβ3 inhibitor with an IC50 value of 0.94 nM. It specifically binds to the αvβ3 integrin on the cell surface, blocking integrin-mediated cell adhesion, migration and signal transduction processes, thereby inhibiting tumor angiogenesis and the invasion and metastasis of tumor cells. Dec 26 2024
E8161 Fasiglifam Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 72 nM. Dec 26 2024
E8162 Nicotinamide riboside Nicotinamide riboside is an orally active NAD(+) precursor essential for cellular energy and metabolic functions. It Supplementation increases NAD(+) levels, activating sirtuins like SIRT1 and SIRT3, which improve oxidative metabolism and provide protection against metabolic issues induced by a high-fat diet. It also helps to reduce cognitive decline in a transgenic mouse model of Alzheimer's disease. Dec 26 2024