All New Products Listed Chronologically

Catalog No.	Product Name	Information	Isotype
E1800	Oxythiamine chloride hydrochloride	Oxythiamine chloride hydrochloride(Hydroxythiamine chloride hydrochloride) is a salt form of Oxythiamine. It is an inhibitor of transketolase, the enzyme that controls the nonoxidative branch of the pentose phosphate pathway. It also suppresses tumor cell proliferation and promotes apoptosis.	May 23 2024
E1385	Bexotegrast	Bexotegrast(PLN-74809) is potent dual selective inhibitor of αvβ6 and αvβ1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-β activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).	May 21 2024
E1607	RK-701	RK-701 is a highly selective, potent, and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM. RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in γ-globin induction. RK-701 is used in the research of sickle cell disease.	May 19 2024
E1632	VU0463271	VU0463271 is a selective and potent antagonist of neuronal-specific potassium-chloride cotransporter 2 KCC2, with an IC50 of 61 nM. VU0463271 demonstrates over 100-fold selectivity compared to the closely related Na-K-2Cl cotransporter 1 (NKCC1).	May 16 2024
E1340	Glesatinib	Glesatinib(MGCD265) is an orally bioavailable potent dual inhibitor of c-MET and SMO. Glesatinib counteracts P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).	May 16 2024