HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E7344 Aurantiamide acetate Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from?Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of ?inflammatory?diseases. Dec 19 2024
E1693 Ryanodine Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Dec 19 2024
E7345 Balaglitazone Balaglitazone is a selective partial PPARγ agonist with an EC50 of 1.351 μM for human PPARγ. Dec 19 2024
E7122 Guanosine 5'-diphosphate disodium salt Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt Dec 19 2024
E7346 NVP-BSK805 NVP-BSK805 is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively. Dec 19 2024
E7123 Seocalcitol Seocalcitol is a vitamin D analog, binds vitamin D receptor protein from human osteosarcoma MG-63 cells with Kd of 0.27 nM. Dec 19 2024
E7347 S-Nitroso-N-acetyl-DL-penicillamine S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation. Dec 19 2024
E7124 Ercalcidiol 0 Dec 19 2024
E5257 Epmedin C Epmedin C, a natural product, has estrogen-like effects for ovariectomized mice. Dec 19 2024
E7125 Vitamin D4 Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol. Dec 19 2024
E7348 Moracin C Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells. Dec 19 2024
E7126 Licochalcone C Licochalcone C could inhibit α-glucosidase, with IC50s of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively. Dec 19 2024
E5267 Sanggenon C Sanggenon C, a flavonoid, exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits mitochondrial fission to induce apoptosis by blocking the ERK signaling pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and TNF-α-stimulated cell adhesion and VCAM-1 expression, by suppressing NF-κB activity. Sanggenon C possesses antioxidant, anti-inflammatory and antitumor activities. Dec 19 2024
E7349 T-1105 T-1105, a structural analogue of T-705, is a novel broad-spectrum viral polymerase inhibitor. T-1105 inhibits the polymerases of RNA viruses after being converted to ribonucleoside triphosphate (RTP) metabolite. T-1105 has antiviral activity against various RNA viruses. T-1105 can be formed by nicotinamide mononucleotide adenylyltransferase. Dec 19 2024
E7127 Vasopressin Vasopressin (Pituitrin) is a neuropeptide that enhances ACTH secretion by potentiating CRH signaling in the pituitary through V1b receptors coupled to calcium–phospholipid pathways. During chronic stress, vasopressin acts as a crucial regulator of the HPA axis, maintaining corticotroph responsiveness and ACTH release even in the presence of elevated glucocorticoid levels. Dec 19 2024
E7350 4-Aminobenzamidine dihydrochloride 4-Aminobenzamidine (p-Aminobenzamidine) dihydrochloride is a strong trypsin inhibitor, also acting as a relatively weak urokinase type plasminogen activator (uPA) inhibitor (Ki=82 μM). 4-Aminobenzamidine can inhibit growth of a human prostate tumor in SCID mice. Dec 19 2024
E5621 Eriocalyxin B Eriocalyxin B is an ent-Kaurene diterpenoid isolated from Chinese herb Isodon eriocalyx. Eriocalyxin B has anti-cancer and anti-infammatory activities. Eriocalyxin B induces cell apoptosis. Dec 19 2024
E7351 KRCA-0008 KRCA-0008 is a selective ALK/Ack1 inhibitor with IC50s of 12 and 4 nM for ALK and Ack1, respectively. KRCA-0008 can be used for the research of cancer. Dec 19 2024
E7128 NPPB NPPB is a blocker of the outwardly rectifying chloride channel (ORCC). Dec 19 2024
E7352 3-Methyl-2-oxovaleric acid 3-Methyl-2-oxovaleric acid is a neurotoxin, an acidogen, and a metabotoxin, and also an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. Dec 19 2024