HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E7295 Dabsyl chloride Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. Dec 19 2024
E7080 Dihomo-γ-linolenic acid Dihomo-γ-linolenic acid (DGLA, all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 polyunsaturated fatty acid (PUFA) derived in vivo from linolenic acid. It exhibits antitumor, anti-inflammatory, and antiproliferative effects, making it a promising candidate for the prevention and treatment of hyperplasia and proliferative diseases, especially for cancers. Dec 19 2024
E7296 Amine-PEG3-Biotin Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group. Dec 19 2024
E7081 Purpurin 18 Purpurin-18 is a chlorophyll-derived dihydroporphyrin, serves as a key precursor for photosensitizers like purpurinimides, which absorb light in the 700–850 nm range. It demonstrate potent photodynamic anti-tumor activity and generates ROS, disrupting mitochondrial membrane potential and inducing apoptosis against triple-negative breast cancer both in vitro and in vivo. Dec 19 2024
E7297 Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride is an oxygen-sensitive fluorescent indicator widely used as a probe for luminescence detection and quantitative oxygen determination. Dec 19 2024
E7082 5(6)-Carboxyfluorescein 5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo. Dec 19 2024
E7298 NSC-87877 NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26). Dec 19 2024
E4965 Dinoprost Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour. Dec 19 2024
E7299 Veratridine Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow. Dec 19 2024
E7083 BTS BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC50s of ~5 μM for actin- and Ca2+-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers. Dec 19 2024
E7300 Sulfanitran Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG). Dec 19 2024
E7084 C6 Ceramide C6 Ceramide (C6-Cer, N-Hexanoylsphingosine) is a short-chain, cell-permeable ceramide with anticancer properties, including cell cycle arrest, apoptosis, and tumor growth inhibition. It enhances chemotherapy efficacy in drug-resistant cancers by promoting miR-29b expression, which suppresses endothelial cell proliferation, migration, and angiogenesis through the Akt signaling pathway. In combination with Trichostatin A, C6 Ceramide disrupts the HDAC6/PP1/tubulin complex, leading to AKT dephosphorylation. Dec 19 2024
E7301 Atrasentan Atrasentan (ABT-627, (+)-A 127722, A-147627) is an antagonist of endothelin A (ETA) receptor with a Ki of 0.034 nM. It exhibits antitumor activity by inhibiting prostate cancer cell growth and inducing apoptotic cell death. Dec 19 2024
E7085 Laurdan Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase. Dec 19 2024
E7302 Nolatrexed dihydrochloride Nolatrexed dihydrochloride (AG 337) is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme, with a Ki of 11 nM for human thymidylate synthase. Nolatrexed dihydrochloride (AG 337) induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity. Dec 19 2024
E7086 Kanamycin Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia. Dec 19 2024
E7303 Telotristat ethyl Telotristat ethyl (LX1032) is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production. Dec 19 2024
E4721 Ammonium tetrathiomolybdate Ammonium tetrathiomolybdate is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate has neuroprotection effects. Ammonium tetrathiomolybdate can be used for the research of brain ischemia. Dec 19 2024
E2927 WST-1 WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm. Dec 19 2024
E7305 Penconazole Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats. Dec 19 2024