WH-4-023

Catalog No.S7565 Synonyms: KIN001-112, KIN112

WH-4-023 Chemical Structure

Molecular Weight(MW): 568.67

WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.

Size Price Stock Quantity  
USD 147 In stock
USD 477 In stock
USD 997 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 2 Publications

1 Customer Review

  • (G-I) WB analysis of total LCK, LCK Y505, and Src Y416 expression in ALL-SIL, CCRF-CEM, and TALL-1. Cells were treated with DMSO only (Ctrl), dasatinib, bosutinib, nintedanib, or WH-4-023 overnight at the compound concentrations corresponding to the GI50 at 48 hr. Bos, bosutinib; Das, dasatinib; Nint, nintedanib; WH, WH-4-023.

    Blood, 2017, 130(25):2750-2761. WH-4-023 purchased from Selleck.

Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
Targets
Lck [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
2 nM 6 nM
In vitro

WH-4-023 shows little activity on p38 and KDR. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human EM-2 cell NFrJclhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYnJdYVuUW6qaXLpeIlwdiCxZjDoeY1idiCHTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{46OWVvMEig{txO NGDONpBUSU6JRWK=
human LAMA-84 cell Mnu1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlKzTY5pcWKrdHnvckBw\iCqdX3hckBNSU2DLUi0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{44QGVvME[g{txO MUfTRW5ITVJ?
human EoL-1-cell cell NYrPUZZPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVPJcohq[mm2aX;uJI9nKGi3bXHuJGVwVC1zLXPlcIwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF06NjVzZT2wOkDPxE1? NWLrS2NDW0GQR1XS
human MEG-01 cell NYHZV217T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYTJcohq[mm2aX;uJI9nKGi3bXHuJG1GTy1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOlNmNTB3IN88US=> M1fITXNCVkeHUh?=
human CTV-1 cell M37ieWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUD2N|FLUW6qaXLpeIlwdiCxZjDoeY1idiCFVG[tNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOTinLUC1JO69VQ>? M3HEVHNCVkeHUh?=
human BL-70 cell NXLB[YlJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoSxTY5pcWKrdHnvckBw\iCqdX3hckBDVC15MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuO|JmNTB3IN88US=> NH3NUYxUSU6JRWK=
human K-562 cell MkXYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3n4WmlvcGmkaYTpc44hd2ZiaIXtZY4hUy13NkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxODF4MjFOwG0> MnPiV2FPT0WU
human BV-173 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn7OTY5pcWKrdHnvckBw\iCqdX3hckBDXi1zN{OgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxODVzNDFOwG0> NGHTVVdUSU6JRWK=
human DOHH-2 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlnjTY5pcWKrdHnvckBw\iCqdX3hckBFV0iKLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlAxODV7NzFOwG0> NGLzNFBUSU6JRWK=
human A704 cell M1;hVmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlWxTY5pcWKrdHnvckBw\iCqdX3hckBCPzB2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFEzPyEQvF2= Ml7mV2FPT0WU
human NCI-SNU-16 cell MnT2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlXFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvU17VMVE3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMUW3NkDPxE1? NGLFOodUSU6JRWK=
human LC-2-ad cell M2nHbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFr6[GRKdmirYnn0bY9vKG:oIHj1cYFvKEyFLUKtZYQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB{MEOzJO69VQ>? M4fySXNCVkeHUh?=
human LB2518-MEL cell MoflS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2\2UmlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMES2Olch|ryP NVu0fohRW0GQR1XS
human D-336MG cell M{LmOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWrCPZlzUW6qaXLpeIlwdiCxZjDoeY1idiCGLUOzOm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNE[4NUDPxE1? M{nvdXNCVkeHUh?=
human LB996-RCC cell NV3iTVk{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHXx[G5KdmirYnn0bY9vKG:oIHj1cYFvKEyEOUm2MXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEW2Olgh|ryP NHz2d3pUSU6JRWK=
human Becker cell NFjTfnRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnXmTY5pcWKrdHnvckBw\iCqdX3hckBD\WOtZYKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA3OzhzIN88US=> MW\TRW5ITVJ?
human LB1047-RCC cell M2ixfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXnUN4VzUW6qaXLpeIlwdiCxZjDoeY1idiCOQkGwOFcuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wO|U6OiEQvF2= NVvrepA2W0GQR1XS
human KS-1 cell NULjZXpuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHX4UFNKdmirYnn0bY9vKG:oIHj1cYFvKEuVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA4PzV6IN88US=> MX3TRW5ITVJ?
human MPP-89 cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3jS[GlvcGmkaYTpc44hd2ZiaIXtZY4hVVCSLUi5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xQDJ{OTFOwG0> M2PRUHNCVkeHUh?=
human RXF393 cell M3j1cmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MY\Jcohq[mm2aX;uJI9nKGi3bXHuJHJZTjN7MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVA3OzNizszN MVXTRW5ITVJ?
LB831-BLC cell M1;kbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGfYO|BKdmirYnn0bY9vKG:oIHj1cYFvKEyEOEOxMWJNSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMUK3NVUh|ryP MVvTRW5ITVJ?
HUTU-80 cell MnjlS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NH61doxKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF5NUK5JO69VQ>? MVTTRW5ITVJ?
A498 cell M1fjOGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnTuTY5pcWKrdHnvckBw\iCqdX3hckBCPDl6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xPFk1PSEQvF2= NWLZVotoW0GQR1XS
MZ1-PC cell M3rNWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHjDUlBKdmirYnn0bY9vKG:oIHj1cYFvKE2cMT3QR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOjJ5MU[g{txO M3LIfnNCVkeHUh?=
TE-8 cell MVPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkfiTY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yN|kzPCEQvF2= M{H4O3NCVkeHUh?=
MFH-ino cell  MnXQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NI\PbHVKdmirYnn0bY9vKG:oIHj1cYFvKE2ISD3pco8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjJ|OUK1JO69VQ>? MYPTRW5ITVJ?
TE-15 cell MmfES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnHhTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zNTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlQzPzZizszN MmLyV2FPT0WU
NTERA-S-cl-D1 cell M{jJR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYL6e2ZzUW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zQDh3NTFOwG0> M{jnfnNCVkeHUh?=
COLO-829 cell NUPlemp1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1K1RWlvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz24Nlkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjNzMkGyJO69VQ>? MkmxV2FPT0WU
SW684 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGjsT|NKdmirYnn0bY9vKG:oIHj1cYFvKFOZNki0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{OjV6ODFOwG0> M2\XfXNCVkeHUh?=
OS-RC-2 cell MmH6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFflTJNKdmirYnn0bY9vKG:oIHj1cYFvKE:VLWLDMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN3MEGxJO69VQ>? MVjTRW5ITVJ?
IST-MES1 cell M3vhUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NULBZZFnUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVUOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwM{W3NlMh|ryP MoG4V2FPT0WU
SNB75 cell Mn;HS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWS0SnNJUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzV5N{Sg{txO M{G1VHNCVkeHUh?=
SW954 cell NIHNe2JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1P3WWlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM4OTZ|IN88US=> MWXTRW5ITVJ?
RCC10RGB cell M1fwc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGXo[4xKdmirYnn0bY9vKG:oIHj1cYFvKFKFQ{GwVmdDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC52Mk[zNUDPxE1? NEHLd25USU6JRWK=
VA-ES-BJ cell MnSyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkmyTY5pcWKrdHnvckBw\iCqdX3hckBXSS2HUz3CTkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPDZ{NjFOwG0> NFe1cYVUSU6JRWK=
NCI-H1648 cell NHXDeJBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{XPZ2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC53MUW4NkDPxE1? M3nIeHNCVkeHUh?=
PF-382 cell NXrUenZvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIHNPY9KdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPzB5NkOg{txO NWTCW49TW0GQR1XS
human Daudi cell NVv5PXBzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1;UZmlvcGmkaYTpc44hd2ZiaIXtZY4hTGG3ZHmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlcyPDFzIN88US=> M1PFeHNCVkeHUh?=
SW982 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX;Jcohq[mm2aX;uJI9nKGi3bXHuJHNYQTh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OVgyQSEQvF2= MYXTRW5ITVJ?
SW872 cell NEPWOWZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlPITY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFY1PThizszN NFvvRXVUSU6JRWK=
TE-12 cell NVLwPYQ2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MY\Jcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64PFg{OSEQvF2= NYLteYFIW0GQR1XS
human HOP-62 cell M1TQbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXGwNY1QUW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjlzNUm5JO69VQ>? M1;ic3NCVkeHUh?=
human NOS-1 cell MknkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHjpOWFKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE46PTB2NTFOwG0> MYLTRW5ITVJ?
human BL-41 cell NIr5XnZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVHJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTRzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6wNFAyOyEQvF2= M1exeHNCVkeHUh?=
human TGBC24TKB cell NWjQWHNxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF\ScopKdmirYnn0bY9vKG:oIHj1cYFvKFSJQlOyOHRMSiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEO4N|Eh|ryP NFvNfm1USU6JRWK=
human KGN cell M2roN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVrJcohq[mm2aX;uJI9nKGi3bXHuJGtIViClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEWyNUDPxE1? NYjJW2dMW0GQR1XS
human TK10 cell NWTveXdRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUfZWGNGUW6qaXLpeIlwdiCxZjDoeY1idiCWS{GwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4xQDRzODFOwG0> NGXjVYxUSU6JRWK=
human GB-1 cell M2XnZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUnOOGxUUW6qaXLpeIlwdiCxZjDoeY1idiCJQj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4yPjB4NDFOwG0> NUHOOWNVW0GQR1XS
human GCIY cell MnSzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoTXTY5pcWKrdHnvckBw\iCqdX3hckBIS0m\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6yN|AyKM7:TR?= MoTRV2FPT0WU
human LXF-289 cell NGfXT5hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX7Jcohq[mm2aX;uJI9nKGi3bXHuJGxZTi1{OEmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI4OjV4IN88US=> NEPHd4hUSU6JRWK=
RL95-2 cell NGXrNZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF\NSGhKdmirYnn0bY9vKG:oIHj1cYFvKFKOOUWtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzJ2M{[g{txO Mk[2V2FPT0WU
human SW962 cell MmHqS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYHJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTZ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6zN|c1OiEQvF2= M4njWXNCVkeHUh?=
human HT-144 cell NVPiSYN3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnfXTY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlQ1PTF5IN8ccS=> Mnu4V2FPT0WU
human IST-SL2 cell MnrBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVnJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2VTEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlQ4PDJzIN88US=> M2S0fXNCVkeHUh?=
human NB6 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmrYTY5pcWKrdHnvckBw\iCqdX3hckBPSjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLk[5Olk5KM7:TR?= MofwV2FPT0WU
human SF126 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGLYOFlKdmirYnn0bY9vKG:oIHj1cYFvKFOIMUK2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU44OzF5ODFOwG0> MX7TRW5ITVJ?
human BOKU cell NX;YSIlWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3L2OWlvcGmkaYTpc44hd2ZiaIXtZY4hSk:NVTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPFA2OjdizszN NWrsPJpxW0GQR1XS
human BB30-HNC cell MomxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVzJcohq[mm2aX;uJI9nKGi3bXHuJGJDOzBvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45PTR5MjFOwG0> Ml\rV2FPT0WU
human KLE cell Mlm3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmrYTY5pcWKrdHnvckBw\iCqdX3hckBMVEViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLki2NlMzKM7:TR?= NFnPT3VUSU6JRWK=
human MLMA cell M{fOPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWTj[401UW6qaXLpeIlwdiCxZjDoeY1idiCPTF3BJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU46OjNzIN88US=> MX3TRW5ITVJ?
human KINGS-1 cell NVriTJQ6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlfHTY5pcWKrdHnvckBw\iCqdX3hckBMUU6JUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU46Pjh7NzFOwG0> MUnTRW5ITVJ?
human ES6 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXPJcohq[mm2aX;uJI9nKGi3bXHuJGVUPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwMEW0NFEh|ryP NGj0bm1USU6JRWK=
human SH-4 cell NUPOWmtuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NInnRmRKdmirYnn0bY9vKG:oIHj1cYFvKFOKLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlEzODV3IN88US=> M1uyT3NCVkeHUh?=
human D-263MG cell NY\zdHJmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFXKb3dKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ6OEWzJO69VQ>? NX3BSohrW0GQR1XS
human SF268 cell NEP4V4lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVHnSVc5UW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPDh4OEKg{txO NFPaR41USU6JRWK=
human NB17 cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4\2W2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOlI5PzVizszN M2jldnNCVkeHUh?=
human DMS-114 cell Mn3sS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlT0TY5pcWKrdHnvckBw\iCqdX3hckBFVVNvMUG0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk44QTB{MjFOwG0> NH2zPZVUSU6JRWK=
MC116 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1n1UmlvcGmkaYTpc44hd2ZiaIXtZY4hVUNzMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlg2PzB2IN88US=> MlXRV2FPT0WU
human NCI-H747 cell M2DEc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlTHTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEe0O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPzRzNUmg{txO M4XzNXNCVkeHUh?=
human A388 cell NFvuSXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGE{QDhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zND62O|U5KM7:TR?= M3HkPXNCVkeHUh?=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 12 mg/mL warmed (21.1 mM)
Ethanol 6 mg/mL warmed (10.55 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+30% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
1mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 568.67
Formula

C32H36N6O4

CAS No. 837422-57-8
Storage powder
in solvent
Synonyms KIN001-112, KIN112

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Src Signaling Pathway Map

Related Src Products0

Tags: buy WH-4-023 | WH-4-023 supplier | purchase WH-4-023 | WH-4-023 cost | WH-4-023 manufacturer | order WH-4-023 | WH-4-023 distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID