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Raleukin

Cat.No.P1235

Anakinra (Raleukin, AMG-719) is an exogenous antagonist of recombinant human interleukin-1 receptor that also inhibits caspase-1 and caspase-9 activity with Ki of 0.201 μM and 0.31 μM respectively. It is used in research to study IL-1 blockade in inflammation, tumor growth, islet transplantation, and cardiac injury models.

Amino-acid Sequence

CAS No. 143090-92-0

Selleck's Raleukin Has Been Cited by 1 Publication

Quality Control

Chemical Information & Solubility

Storage (From the date of receipt)	2 years -20°C liquid	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

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Biological Activity

Description	Anakinra (Raleukin, AMG-719) is an exogenous antagonist of recombinant human interleukin-1 receptor that also inhibits caspase-1 and caspase-9 activity with Ki of 0.201 μM and 0.31 μM respectively. It is used in research to study IL-1 blockade in inflammation, tumor growth, islet transplantation, and cardiac injury models.

References
https://pubmed.ncbi.nlm.nih.gov/18474815/#&dopt=Abstract https://pubmed.ncbi.nlm.nih.gov/12196041/

References

https://pubmed.ncbi.nlm.nih.gov/18474815/#&dopt=Abstract
https://pubmed.ncbi.nlm.nih.gov/12196041/

Product Information

Molecular Weight	17257.60
CAS No.	143090-92-0
Storage (From the date of receipt)	2 years -20°C liquid
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)