research use only

Abaloparatide (BA058)

Cat.No.P1092

Abaloparatide (BA058, BIM-44058, ITM-058) is a novel 34-amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway with an IC50 of 0.117 nM in SOST analysis.

Amino-acid Sequence

Abaloparatide (BA058) Amino-acid Sequence

CAS No. 247062-33-5 (acetate)

Selleck's Abaloparatide (BA058) Has Been Cited by 1 Publication

Quality Control

Batch: P109201 DMSO] 80 mg/mL] false] Water] 80 mg/mL] false] Ethanol] Insoluble] false Purity: 98.04%
98.04

Chemical Information & Solubility

Storage (From the date of receipt) 3 years-20°C powder

In vitro
Batch:

DMSO : 80 mg/mL (19.89 mM);
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 80 mg/mL

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Biological Activity

Description

Abaloparatide (BA058, BIM-44058, ITM-058) is a novel 34-amino acid peptide selected to be a potent and selective activator of the parathyroid hormone receptor (PTH1R) signaling pathway with an IC50 of 0.117 nM in SOST analysis.

Targets/IC50/Ki
PTH1R

References

  • https://tspace.library.utoronto.ca/handle/1807/103220
  • https://pubmed.ncbi.nlm.nih.gov/27748532/

Product Information

Molecular Formula

C176H304N56O51

Molecular Weight 4020.709
CAS No. 247062-33-5 (acetate)
Appearance White Powder
Peptide Content (by %N) ≥80%
Single Impurity (by HPLC) ≤1.0%
Assay (By Anhydrous, Acetic Acid-free) 95.0~105.0%
MS Consistent
Packing plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt)
3 years-20°C powder
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)