Degarelix acetate (ASP-3550 acetate) is a potent and long-acting luteinizing hormone-releasing hormone (LHRH) antagonist.

Amino-acid Sequence

CAS No. 214766-78-6

Batch: P109401 DMSO] 33 mg/mL] false] Water] 33 mg/mL] false] Ethanol] Insoluble] false Purity: 99.94%

99.94

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 33 mg/mL ( (20.21 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 33 mg/mL

Ethanol : Insoluble

In vivo
Batch:

Add solvents to the product individually and in order.

Description	Degarelix acetate (ASP-3550 acetate) is a potent and long-acting luteinizing hormone-releasing hormone (LHRH) antagonist.

In Vivo
In vivo	Degarelix acetate is a member of a new class of long-acting gonadotropin-releasing hormone (GnRH) antagonists, possessing a long duration of luteinizing hormone (LH) and testosterone suppression.^[2]
Animal Research	Animal Models	castrated male rat model
	Dosages	50 μg
	Administration	--

References
[1] Broqua P, et al. J Pharmacol Exp Ther. 2002 Apr;301(1):95-102. [2] Jiang G, et al. J Med Chem. 2001 Feb 1;44(3):453-67.

References

Molecular Formula:	C₈₂H₁₀₃ClN₁₈O₁₆
Molecular Weight:	1632.26
CAS No.:	214766-78-6
Appearance:	White Powder
Peptide Content (by %N):	≥80%
Single Impurity (by HPLC):	≤1.0%
Assay (By Anhydrous, Acetic Acid-free):	95.0~105.0%
MS:	Consistent
Packing:	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt):	3 years-20°C powder
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)