research use only

TMPyP4 tosylate

Cat.No.P1202

TMPyP4 tosylate (TMP 1363), a quadruplex-specific ligand, inhibits the interaction between G-quadruplex (G4) and IGF-1 (Insulin-like growth factor type I). TMPyP4 tosylate is also a telomerase inhibitor with antitumor effects.

Amino-acid Sequence

CAS No. 36951-72-1

Selleck's TMPyP4 tosylate Has Been Cited by 1 Publication

Quality Control

Batch: P120201 Water] 50 mg/mL] false] ] ] false] ] ] false Purity: 98.73%

98.73

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

Water : 50 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	TMPyP4 tosylate (TMP 1363), a quadruplex-specific ligand, inhibits the interaction between G-quadruplex (G4) and IGF-1 (Insulin-like growth factor type I). TMPyP4 tosylate is also a telomerase inhibitor with antitumor effects.
Targets/IC₅₀/Ki	G-quadruplex IGF-1 telomerase

References
https://pubmed.ncbi.nlm.nih.gov/30278241/ https://pubmed.ncbi.nlm.nih.gov/21590716/

References

https://pubmed.ncbi.nlm.nih.gov/30278241/
https://pubmed.ncbi.nlm.nih.gov/21590716/

Product Information

Molecular Formula	C₇₂H₆₆N₈O₁₂S₄
Molecular Weight	1363.6
CAS No.	36951-72-1
Appearance	White Powder
Peptide Content (by %N)	≥80%
Purity (by HPLC)	0.9873
Single Impurity (by HPLC)	≤1.0%
Assay (By Anhydrous, Acetic Acid-free)	95.0~105.0%
MS	Consistent
Packing	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt)	3 years-20°C powder
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)