Bax inhibitor peptide V5 (BIP-V5 , BAX Inhibiting Peptide V5) is a cell-permeable pentapeptide that blocks the ku70 binding domain and prevents Bax conformational change and mitochondrial translocation. It Inhibits Bax-mediated apoptosis.

Amino-acid Sequence

CAS No. 579492-81-2

Purity & Quality Control

Batch: P107901 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] 100 mg/mL] false Purity: 99.88%

99.88

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (170.41 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	Bax inhibitor peptide V5 (BIP-V5 , BAX Inhibiting Peptide V5) is a cell-permeable pentapeptide that blocks the ku70 binding domain and prevents Bax conformational change and mitochondrial translocation. It Inhibits Bax-mediated apoptosis.

References
[1] Sawatzky DA, et al. Am J Pathol. 2006;168(1):33-41.

References

[1] Sawatzky DA, et al. Am J Pathol. 2006;168(1):33-41.

Product Information

Molecular Formula:	C₂₇H₅₀N₆O₆S
Molecular Weight:	586.79
CAS No.:	579492-81-2
Appearance:	White Powder
Peptide Content (by %N):	≥80%
Purity (by HPLC):	>99%
Single Impurity (by HPLC):	≤1.0%
Assay (By Anhydrous, Acetic Acid-free):	95.0~105.0%
MS:	Consistent
Packing:	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt):	3 years-20°C powder
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)