Carbetocin Acetate is a long-acting oxytocin-analogue and a potent agonist of the oxytocin receptor (OXTR), with improved in vivo stability over oxytocin.

Amino-acid Sequence

CAS No. 37025-55-1

Purity & Quality Control

Batch: Purity: 99.86%

99.86

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (101.19 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	Carbetocin Acetate is a long-acting oxytocin-analogue and a potent agonist of the oxytocin receptor (OXTR), with improved in vivo stability over oxytocin.

In vitro
In vitro	Carbetocin Acetate is a long-acting oxytocin-analogue and a potent agonist of the oxytocin receptor (OXTR), with higher affinity to the chimeric N-terminus (E1) receptor.^[1]

In Vivo
In vivo	In the forced swim test, Carbetocin produces antidepressant-like changes in behavior via activation of oxytocin receptors in the CNS.^[2]

References
[1] Gimpl G, et al. Eur J Pharmacol. 2005 Mar 7;510(1-2):9-16. [2] Chaviaras S, et al. Psychopharmacology (Berl). 2010 May;210(1):35-43.

References

Product Information

Molecular Formula:	C₄₅H₆₉N₁₁O₁₂S
Molecular Weight:	988.16
CAS No.:	37025-55-1
Appearance:	White Powder
Peptide Content (by %N):	≥80%
Purity (by HPLC):	>98%
Single Impurity (by HPLC):	≤1.0%
Assay (By Anhydrous, Acetic Acid-free):	95.0~105.0%
MS:	Consistent
Packing:	plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage (From the date of receipt):	3 years-20°C powder
Shipping:	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)