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Disitertide(P144)

Cat.No.P1218

Disitertide (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor, is also a PI3K inhibitor and an apoptosis inducer.

Amino-acid Sequence

Disitertide(P144) Amino-acid Sequence

CAS No. 272105-42-7

Quality Control

Batch: P121801 DMSO] 25 mg/mL] false] Water] Insoluble] false] Ethanol] Insoluble] false Purity: 98.38%
98.38

Chemical Information & Solubility

Storage (From the date of receipt) 3 years-20°C powder

In vitro
Batch:

DMSO : 25 mg/mL (15.81 mM)；
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Biological Activity

Description Disitertide (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor, is also a PI3K inhibitor and an apoptosis inducer.
Targets/IC50/Ki
TGF-β1
PI3K

References
  • https://pubmed.ncbi.nlm.nih.gov/26720517/
  • https://pubmed.ncbi.nlm.nih.gov/30864698/

Product Information

Molecular Formula

C68H109N17O22S2
Molecular Weight 1580.83
CAS No. 272105-42-7
Appearance White Powder
Peptide Content (by %N) ≥80%
Single Impurity (by HPLC) ≤1.0%
Assay (By Anhydrous, Acetic Acid-free) 95.0~105.0%
MS Consistent
Packing plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt)		 3 years-20°C powder
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)