Ferroptosis

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7243 Ferrostatin-1 (Fer-1) <1 mg/mL 52 mg/mL 52 mg/mL
S7699 Liproxstatin-1 <1 mg/mL 68 mg/mL 21 mg/mL
S7242 Erastin <1 mg/mL 19 mg/mL <1 mg/mL
S8254 FIN56 <1 mg/mL 100 mg/mL <1 mg/mL
S8155 RSL3 <1 mg/mL 88 mg/mL 22 mg/mL

Ferroptosis Products

Catalog No. Information Product Use Citations Product Validations
S7243

Ferrostatin-1 (Fer-1)

Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.

S7699

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

S7242

Erastin

Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS.

S8254

FIN56

FIN56 is a specific inducer of ferroptosis .

S8155

RSL3

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.

Catalog No. Information Product Use Citations Product Validations
S7243

Ferrostatin-1 (Fer-1)

Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM.

S7699

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Catalog No. Information Product Use Citations Product Validations
S7242

Erastin

Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS.

2017, 551(7682):639-643

2018, 154(5):1480-1493

2017, 153(5):1429-1443

S8254

FIN56

FIN56 is a specific inducer of ferroptosis .

S8155

RSL3

RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.

2019, 567(7746):118-122

2017, 547(7664):453-457

2017, 171(3):628-641