| S4226 |
Minocycline Hydrochloride
|
Minocycline HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.
|
-
Cell Rep, 2025, 44(8):116015
-
Hum Cell, 2025, 38(4):110
-
Brain Res Bull, 2025, 234:111655
|
|
| S1408 |
Linezolid (PNU-100766)
|
Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections.
|
-
Commun Biol, 2025, 8(1):1261
-
Molecules, 2023, 28(6)2820
-
Molecules, 2023, 28(6), 2820
|
|
| S6068 |
Doxycycline monohydrate
|
Doxycycline is a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity.
|
-
iScience, 2024, 27(3):109265
-
Mol Cancer, 2022, 21(1):43
-
Theranostics, 2022, 12(7):3131-3149
|
|
| S1450 |
Nanchangmycin
|
Nanchangmycin is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for mammals and plants.
|
-
Elife, 2022, 11e74513
-
Antimicrob Agents Chemother, 2020, 1;AAC.00289-20
-
Sci Rep, 2019, 9(1):1144
|
|
| S5206 |
Benzylpenicillin potassium
|
Benzylpenicillin potassium (Penicillin G potassium) is the potassium salt form of penicillin G, a broad-spectrum penicillin antibiotic.
|
-
Foods, 2025, 1580
-
Foods, 2025, 14(9)1580
-
Therapeutic Drug Monitoring, 2023, 667-674
|
|
| S4056 |
Retapamulin
|
Retapamulin (SB-275833) is a topical antibiotic, which binds to both E. coli and S. aureus ribosomes with similar potencies with Kd of 3 nM.
|
-
Infect Drug Resist, 2023, 16:4867-4879
-
Infection and Drug Resistance, 2023, 4867-4879
-
Pediatr Infect Dis J, 2021, 40(7):637-638
|
|
| S2152 |
Sitafloxacin Hydrate
|
Sitafloxacin Hydrate (DU-6859a) is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.
|
-
iScience, 2024, 27(10):110862
-
mSphere, 2018, 3(5)
-
mSphere, 2018, e00422-18
|
|
| S4641 |
Tedizolid Phosphate
|
Tedizolid (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.
|
-
Journal of the Association for Research in Otolaryngology, 2024, 259-275
-
Int Arch Allergy Immunol, 2023, 184(9):932-948
-
Molecular Systems Biology, 2021, e10426
|
|
| S1374 |
Doripenem Hydrate
|
Doripenem Hydrate (S-4661) is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.
|
-
Communications Medicine, 2025, Article number: 1136
-
Antibiotics, 2022, 1298
-
ACS Chem Biol, 2018, 13(8):2020-2026
|
|
| S5531 |
Doripenem
|
Doripenem(S 4661) is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.
|
-
Communications Medicine, 2025, Article number: 1136
-
Antibiotics -Basel, 2022, 11-101298
-
Biomed Chromatogr, 2017, 31(5)
|
|
| S4222 |
Piperacillin Sodium
|
Piperacillin (CL227193,Pipracil) is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.
|
-
Cancer Discovery, 2020, 1722-1741
-
Cancer Discov, 2020, CD-20-0160
-
Analytical Methods, 2018, 10.1039/C8AY00150B
|
|
| S3059 |
Enrofloxacin
|
Enrofloxacin (BAY-Vp2674, PD160788) is a fluoroquinolone antibiotic.
|
-
Cell Metabolism, 2025, 1852-1869.e8
-
Pharmaceutics, 2024, 16(7)903
|
|
| S2539 |
Lomefloxacin HCl
|
Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.
|
-
Frontiers in Immunology, 2022, 918731
-
Front Microbiol, 2020, 10:2936
|
|
| S4158 |
Ceftriaxone disodium salt hemi (heptahydrate)
|
Ceftriaxone disodium salt hemi (heptahydrate) is a third-generation cephalosporin antibiotic.
|
-
Biosensors (Basel), 2024, 14(3)129
-
J Neurochem, 2020, 155(4):370-389
|
|
| S1381 |
Meropenem
|
Meropenem (SM 7338) is an ultra-broad spectrum injectable antibiotic. This compound is used to treat a variety of bacterial infections. It is effective against both Gram-positive and Gram-negative bacteria. This chemical is often reserved for severe or high-risk cases due to its broad activity.
|
-
NPJ Antimicrob Resist, 2025, 3(1):12
|
|
| S4082 |
Spiramycin
|
Spiramycin (Formacidine) is a 16-membered ring macrolide (antibiotic).
|
-
Chemistry, 2020, 10.1002/chem.201905599
|
|
| S3105 |
Nadifloxacin
|
Nadifloxacin (OPC-7251) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.
|
-
Pharmaceutics, 2021, 13(8)1289
|
|
| S4234 |
Capreomycin Sulfate
|
Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.
|
-
Mol Cell Proteomics, 2019, 18(2):231-244
|
|
| S5328 |
Gamithromycin
|
Gamithromycin (ML-1709460) is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease.
|
-
Hum Cell, 2020, 10.1007/s13577-020-00420-z
|
|
| S2583 |
Thiamphenicol
|
Thiamphenicol (Thiophenicol,Dextrosulphenidol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.
|
-
J Immunother Cancer, 2024, 12(11)e009805
|
|
| S3971 |
Fusidine
|
Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
|
-
Infect Drug Resist, 2023, 16:4867-4879
|
|
| S6423 |
Tildipirosin
|
Tildipirosin is a 16-membered ring, tribasic and semi-synthetic macrolide antibiotic.
|
-
Nat Cell Biol, 2017, 19(10):1274-1285
|
|
| E8174 |
Streptomycin
|
Streptomycin (Agrept, Agrimycin, Streptomycin A) is an aminoglycoside antibiotic isolated from Streptomyces griseus and used in tuberculosis (TB) research due to its activity against Mycobacterium tuberculosis. It is also a bactericidal agent useful for studying various bacterial infections.
|
-
Antibodies (Basel), 2024, 13(4)101
|
|
| S1371 |
Cefoselis Sulfate
|
Cefoselis (FK 037 Sulfate) is a widely used beta-lactam antibiotic.
|
|
|
| S2159 |
Tebipenem Pivoxil (L084)
|
Tebipenem pivoxil (L-084, ME1211,TBPM-PI,LJC 11036) is an oral carbapenem antibiotic, use to treat otolaryngologic and respiratory infections.
|
|
|
| S1777 |
Ethionamide
|
Ethionamide (Bayer 5312) is an antibiotic used in the treatment of tuberculosis.
|
|
|
| S1499 |
Cefaclor monohydrate
|
Cefaclor monohydrate(Cefachlor, Cefaclorum) is a cephalosporin antibiotic.
|
|
|
| S2530 |
7-Aminocephalosporanic acid
|
7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
|
|
|
| S1770 |
Sulfadiazine
|
Sulfadiazine is a sulfonamide antibiotic.
|
|
|
| S2048 |
Clindamycin Phosphate
|
Clindamycin Phosphate (NSC 618653) is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.
|
|
|
| S3055 |
Besifloxacin HCl
|
Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
|
|
|
| S1977 |
Sarafloxacin HCl
|
Sarafloxacin HCl (A-56620) is a hydrochloride salt form of sarafloxacin which is a quinolone antibiotic drug with IC50 of 0.96 μg/L.
|
|
|
| S4254 |
Apramycin Sulfate
|
Apramycin Sulfate (Ai3-29795) is an aminoglycoside antibiotic, which binds to the deep groove of the RNA.
|
|
|
| E6075New |
Penicillin G benzathine tetrahydrate
|
Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) is a long-acting beta-lactam antibiotic effective against many bacterial infections such as impetigo.
|
|
|
| S5035 |
6-Aminopenicillanic acid
|
6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin.
|
|
|
| S4865 |
Cefetamet pivoxil hydrochloride
|
Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic.
|
|
|
| E4802 |
Ticarcillin disodium
|
Ticarcillin disodium is a semisynthetic β-lactam antibiotic, which is active against Pseudomonas aeruginosa, Escherichia coli, Pseudomonas mirabilis, Pseudomonas rettgeri, and Klebsiella aerogenes.
|
|
|
| S4122 |
Tilmicosin
|
Tilmicosin (EL 870,LY-177370) is a macrolide antibiotic.
|
|
|
| S5719 |
Ceftizoxime sodium
|
Ceftizoxime sodium(SKF-88373) is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
|
|
|
| S5207 |
Cephalexin Monohydrate
|
Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity.
|
|
|
| S4585 |
Succinylsulfathiazole
|
Succinylsulfathiazole (Succinylsulphathiazole), a sulfonamide, is an antibiotic.
|
|
|
| S8418 |
Phleomycin D1
|
Phleomycin D1(PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. It causes cell death by binding and cleaving DNA. It shows antiproliferative activities and strong cytotoxicity against HT-29 cells.
|
|
|
| S5333 |
Sulbenicillin Sodium
|
Sulbenicillin Sodium (Sulfocillin, Sulfobenzylpenicillin) is the sodium salt of sulbenicillin, which is a penicillin antibiotic.
|
|
|
| S4150 |
Orbifloxacin
|
Orbifloxacin(CP-104354) is a synthetic broad-spectrum fluoroquinolone antibiotic.
|
|
|
| S4421 |
Josamycin
|
Josamycin (EN-141, Kitasamycin A3, Leucomycin A3, Turimycin A5) is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
|
|
|
| S5968 |
Kasugamycin hydrochloride hydrate
|
Kasugamycin (Ksg) hydrochloride hydrate, an antibiotic which binds both the 30S and 70S ribosome, specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs.
|
|
|
| S5290 |
Ormetoprim
|
Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture.
|
|
|
| S5294 |
Cephalotin acid
|
Cephalotin acid (Cephalothin, Cefalotin, Cephalothinum) is a cephalosporin antibiotic.
|
|
|
| S4612 |
Dapson
|
Dapson (Dapsone, 4,4′-Diaminodiphenyl sulfone, 4,4′-Sulfonyldianiline, 4-Aminophenyl sulfone, Bis(4-aminophenyl) sulfone, DDS), also known as diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy.
|
|
|
| S5601 |
Balofloxacin Dihydrate
|
Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic.
|
|
|
| S3645 |
Kitasamycin
|
Kitasamycin (Leucomycin) is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens.
|
|
|
| S6562 |
KKL-35
|
KKL-35 inhibits the trans-translation tagging reaction with an IC50 of 0.9 µM. It has broad-spectrum antibiotic activity.
|
|
|
| E4877 |
Lefamulin
|
Lefamulin (BC-3781), is a pleuromutilin antibiotic, inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. It is effective against a range of gram-positive pathogens involved in community-acquired bacterial pneumonia (CABP), including Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Legionella pneumophila, Chlamydophila pneumoniae, Staphylococcus aureus (including methicillin-resistant and vancomycin-intermediate strains), and vancomycin-resistant Enterococcus faecium.
|
|
|
| S5299 |
Tosufloxacin p-Toluenesulfonate Hydrate
|
Tosufloxacin (T-3262) is a fluoroquinolone antibiotic that is used to treat susceptible infections.
|
|
|
| E4906 |
Cefadroxil
|
Cefadroxil(BL-S 578) is a first-generation, cephalosporin antibiotic with broad spectrum of anti-bacterial activity. It can be used in the management of infections in the respiratory tract, urinary tract, skin and soft tissues, and bones and joints.
|
|
|
| S5421 |
Fluoroquinolonic Acid
|
Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent.
|
|
|
| S6582 |
Ozenoxacin
|
Ozenoxacin(T-3912) is a quinolone antibiotic used for the treatment of impetigo.
|
|
|
| S4870 |
Cefodizime Sodium
|
Cefodizime Sodium, a third generation cephalosporin antibiotic, has broad-spectrum activity and is stable to most beta-lactamases.
|
|
|
| S4978 |
Azathramycin
|
Azathramycin (Azaerythromycin A, Azaerythromycin) is a macrolide antibiotic containing cladinose.
|
|
|
| S5041 |
Difloxacin hydrochloride
|
Difloxacin is a second-generation, synthetic fluoroquinolone antimicrobial antibiotic used in veterinary medicine.
|
|
|
| S5657 |
Ertapenem sodium
|
Ertapenem Sodium (MK826) is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.
|
|
|
| S4671 |
Cefradine
|
Cefradine (Cephradine, Sefril, Anspor, Velosef) is a semi-synthetic cephalosporin antibiotic.
|
|
|
| E6061New |
Cefamandole sodium
|
Cefamandole (sodium) is a parenteral, broad-spectrum, second-generation cephalosporin antibiotic effective against various gram-positive and gram-negative bacteria, including Neisseria, Haemophilus, and Proteus species.
|
|
|
| E4847 |
Tosufloxacin
|
Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. This compound effectively targets a broad spectrum of antibacterial activity, including both gram-positive and gram-negative strains.
|
|
|
| E6052New |
Enrofloxacin hydrochloride
|
Enrofloxacin hydrochloride is a fluoroquinolone antibiotic with potent activity against Mycoplasma bovis, showing an MIC₉₀ of 0.312 μg/mL. It can be used in research to study treatments for pneumonia, mastitis, arthritis, and other conditions in cattle.
|
|
|
| E0706 |
Gemifloxacin mesylate
|
Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate) is a novel fluoronaphthyridone with a broad spectrum of antimicrobial activity and enhances activity against gram-positive aerobes.
|
|
|
| S5573 |
Tilmicosin phosphate
|
Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.
|
|
|
| S4540 |
Sisomicin sulfate
|
Sisomicin sulfate is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of the genus Micromonospora.
|
|
|
| S5744 |
Spiramycin I
|
Spiramycin I (Foromacidin A) is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity.
|
|
|
| S5351 |
Cefmetazole sodium
|
Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
|
|
|
| S5859 |
Sancycline
|
Sancycline (Bonomycin, Norcycline, GS 2147) is a semi-synthetic tetracycline antibiotic.
|
|
|
| S4812 |
Ceftizoxime
|
Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
|
|
|
| S5108 |
Tylosin
|
Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
|
|
|
| S4847 |
Faropenem Sodium
|
Faropenem sodium is an orally active beta-lactam antibiotic that has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
|
|
|
| S1208 |
Doxorubicin (Adriamycin) Hydrochloride
|
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase II with IC50 of 2.67 μM. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.Doxorubicin (Adriamycin) HCl can be used to induce animal models of kidney disease.
|
-
Cell Res, 2025, 35(6):437-452.
-
Nat Commun, 2025, 16(1):8873
-
Nat Commun, 2025, 16(1):509
|
|
| S5159 |
Doxycycline
|
Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.
|
-
Nature, 2025, 10.1038/s41586-025-09222-5
-
Cell Stem Cell, 2025, S1934-5909(25)00181-X
-
Nat Commun, 2025, 16(1):7898
|
|
| S1835 |
Azithromycin
|
Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
|
-
Commun Biol, 2025, 8(1):1261
-
Nat Commun, 2024, 15(1):6579
-
Int Immunopharmacol, 2024, 137:112426
|
|
| S1373 |
Daptomycin
|
Daptomycin is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
|
-
Molecules, 2023, 28(2)621
-
Infect Drug Resist, 2023, 16:4867-4879
-
Microbiol Spectr, 2023, e0092023.
|
|
| S1636 |
Amphotericin B
|
Amphotericin B (AMB, NSC 527017) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.
|
-
PLoS Pathog, 2025, 21(5):e1013220
-
Antimicrob Agents Chemother, 2025, 69(9):e0042725
-
Parasit Vectors, 2024, 17(1):536
|
|
| S1741 |
Rifabutin (LM427)
|
Rifabutin (LM427, Ansamycin) is a semisynthetic ansamycin antibiotic, which is used in the treatment of Mycobacterium avium intracellulare (MAI) and tuberculosis.
|
-
International Journal of Molecular Sciences, 2022, 7383
-
Int J Mol Sci, 2022, 23(13)7383
-
Int J Mol Sci, 2022, 23(22)13809
|
|
| S3015 |
Amoxicillin
|
Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.
|
-
Therapeutic Drug Monitoring, 2023, 625-632
-
Ther Drug Monit, 2023, 10.1097/FTD.0000000000001100
-
J Pharm Biomed Anal, 2022, 219:114904
|
|
| S2565 |
Amoxicillin Sodium
|
Amoxicillin Sodium (Clavulanate,Amoxycillin sodium) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
|
-
J Pharm Biomed Anal, 2022, 219:114904
-
ChemMedChem, 2022, e202200043
-
ChemMedChem, 2022, e202200043
|
|
| S4030 |
Gentamicin Sulfate
|
Gentamycin Sulfate (NSC-82261, SCH9724) is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms.Gentamicin Sulfate can be used to induce animal models of Renal Failure.
|
-
Nat Commun, 2024, 15(1):6579
-
Pharmacol Res, 2024, 201:107096
-
bioRxiv, 2023, 10.1101/2023.08.03.551753
|
|
| S4848 |
Dalbavancin
|
Dalbavancin is a lipoglycopeptide antibiotic that has bactericidal activity against Gram-positive bacteria including various staphylococci.
|
-
Cell Rep, 2022, 39(11):110945
-
Cell Reports, 2022, 110945
-
Frontiers in Microbiology, 2022, 884034
|
|
| S3170 |
Ampicillin sodium
|
Ampicillin(D-(-)-α-Aminobenzylpenicillin sodium salt) is a beta-lactam antibiotic that is part of the aminopenicillin family.
|
-
Heliyon, 2024, 10(11):e32571
-
Heliyon, 2024, e32571
-
Exp Ther Med, 2022, 23(3):216
|
|
| S1399 |
Teicoplanin
|
Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.
|
-
Front Microbiol, 2022, 13:884034
-
ACS Omega, 2022, 7(48):43657-43664
-
Bioeng Transl Med, 2021, 6(1):e10196
|
|
| S2574 |
Tetracycline HCl
|
Tetracycline HCl (NCI-c55561) is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.
|
-
Nat Commun, 2024, 15(1):2377
-
Antiviral Res, 2020, 185:104993
-
PLoS Pathog, 2020, 16;16(3):e1008341
|
|
| S3122 |
Amikacin hydrate
|
Amikacin(BAY416651 hydrate) is an aminoglycoside antibiotic used to treat different types of bacterial infections.
|
-
Cancer Research Communications, 2025, 906-920
-
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
-
Cell & Bioscience, 2024, 71
|
|
| S5535 |
Moxifloxacin
|
Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.
|
-
Microorganisms, 2022, 10(7)1421
-
Transl Vis Sci Technol, 2018, 7(2):11
-
J Pharmacol Toxicol Methods, 2017, 90:39-47
|
|
| S4148 |
Ampicillin Trihydrate
|
Ampicillin Trihydrate (NCI-C56086,D-(-)-α-Aminobenzylpenicillin trihydrate) is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.
|
-
ACS Infect Dis, 2024, 10(12):4087-4102
-
Front Vet Sci, 2022, 9:994652
-
Frontiers in Veterinary Science, 2022, 994652
|
|
| S1502 |
Cephalexin
|
Cephalexin (Cefalexin) is an antibiotic that can treat a number of bacterial infections.
|
-
Clin Cancer Res, 2018, 24(3):659-673
-
Blood Cancer J, 2017, 10.1038/bcj.2017.61
-
Theranostics, 2017, 7(7):2092-2107
|
|
| S1635 |
Erythromycin
|
Erythromycin (E-Mycin) is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).
|
-
Autophagy, 2025, 1-17.
-
Infect Drug Resist, 2023, 16:4867-4879
-
J Med Chem, 2018, 61(9):4189-4202
|
|
| S2315 |
Kanamycin sulfate
|
Kanamycin sulfate (Kanamycin monosulfate, Ophtalmokalixan) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.
|
-
Heliyon, 2024, 10(11):e32571
-
Heliyon, 2024, e32571
-
Oncotarget, 2018, 9(40):26086-26095
|
|
| S5784 |
Vancomycin
|
Vancomycin is an antibiotic used to treat serious bacterial infections. It works by stopping the growth of bacteria.
|
-
Infect Drug Resist, 2023, 16:4867-4879
-
Ann Palliat Med, 2021, 10(2):1748-1754
-
Gut Microbes, 2020, 12(1):1-20
|
|
| S1505 |
Aztreonam
|
Aztreonam (SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection.
|
-
Antimicrob Agents Chemother, 2023, 10.1128/aac.00921-23
-
PLoS Pathog, 2016, 12(10):e1005932
-
Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
|
|
| S3129 |
Trimethoprim
|
Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
|
-
Cell Rep, 2024, 43(7):114500
-
Sci Rep, 2024, 14(1):9167
-
CHALMERS UNIVERSITY OF TECHNOLOGY, 2023,
|
|
| S4093 |
Bismuth Subcitrate Potassium
|
Bismuth Subcitrate is an antibiotic used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.
|
-
Cell Rep, 2022, 38(6):110359
-
J Clin Invest, 2020, 130(7):3901-3918
-
The Journal of Clinical Investigation, 2020, 3901-3918
|
|
| S4885 |
Taurolidine
|
Taurolidine (Taurolin, Tauroline, Tauroflex) is a synthetic broad-spectrum antibiotic with antibacterial, anticoagulant and potential antiangiogenic activities.
|
-
iScience, 2024, 27(10):110862
-
iScience, 2024, 110862
-
Oncology Reports, 2018, 3743-3751
|
|
| S4720 |
Cefotaxime
|
Cefotaxime(HR-756) is a third-generation cephalosporin antibiotic and has broad spectrum activity against Gram positive and Gram negative bacteria.
|
-
Biosensors (Basel), 2024, 14(3)129
-
J Biol Chem, 2023, 299(6):104710
-
Carleton University, 2023, 10.22215/etd/2023-15364
|
|
| S5330 |
Amikacin Sulfate Salt
|
Amikacin (BAY 41-6551) sulfate, a semisynthetic analog of kanamycin, is an aminoglycoside antibiotic which is very active against most gram-negative bacteria including gentamicin- and tobramycin-resistant strains.
|
-
Cell & Bioscience, 2024, 71
-
Microorganisms, 2022, 1421
-
Microorganisms, 2022, 10(7)1421
|
|
| S4279 |
Demeclocycline HCl
|
Demeclocycline HCl(Demeclocycline hydrochloride) is a tetracycline antibiotic via inhibition of protein synthesis by bacteria, used for the treatment of bacterial infections.
|
-
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
-
J Biol Chem, 2020, 10.1074/jbc.RA119.011633.
-
Sci Rep, 2018, 8(1):7653
|
|
| S1605 |
Cefdinir
|
Cefdinir (FK 482, PD 134393, CI-983) is an oral cephalosporin antibiotic, used to treat bacterial infections in many different parts of the body.
|
-
Analytical Chemistry, 2025, 17472-17480
-
Cancers (Basel), 2023, 15(8)2373
|
|
| S1773 |
Oxytetracycline (Terramycin)
|
Oxytetracycline (Terramycin) is a broad-spectrum tetracycline antibiotic used to treat infections with bacteria.
|
-
Sci Rep, 2018, 8(1):7653
-
Front Microbiol, 2016, 7: 1765
|
|
| S2506 |
Roxithromycin
|
Roxithromycin (Roxl-150, Roxo, Surlid, Rulide, Biaxsig, Roxar, Roximycin, Roxomycin, Tirabicin, Coroxin,RU-28965) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.
|
-
Chemistry, 2020, 10.1002/chem.201905599
-
J Med Chem, 2018, 61(9):4189-4202
|
|
| S5533 |
Tobramycin sulfate
|
Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.
|
-
Oncotarget, 2018, 9(40):26086-26095
-
Oncotarget, 2018, 26086-26095
|
|
| S5268 |
Solithromycin
|
Solithromycin (CEM-101, OP-1068), belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
|
-
Nat Commun, 2024, 15(1):6579
-
bioRxiv, 2023, 10.1101/2023.08.03.551753
|
|
| S5491 |
Lomefloxacin
|
Lomefloxacin(SC47111A) is a fluoroquinolone antibiotic used to treat bacterial infections.
|
-
Front Immunol, 2022, 13:918731
-
Frontiers in Immunology, 2022, 918731
|
|
| S4160 |
Penicillin G Sodium
|
Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.
|
-
Front. Oncol, 2023-, Volume 13
-
Cell Rep, 2015, 11(1):98-110
|
|
| S1395 |
Polymyxin B sulphate
|
Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.
|
-
NPJ Antimicrob Resist, 2025, 3(1):12
-
Free Radic Biol Med, 2019, 137:24-36
|
|
| S5298 |
Amoxicillin trihydrate
|
Amoxicillin (Amoxil, Amoxipen, Moxaline) is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.
|
-
ChemMedChem, 2022, e202200043
-
PLoS Comput Biol, 2020, 16(12):e1008489
|
|
| S4986 |
Latamoxef sodium
|
Latamoxef sodium (Moxalactam Disodium, FestamoxinLy, Shiomarin, Ly 127935, 6059 S) is an antibiotic and has anti-bacterial and anti-inflammation effects.
|
-
Cancer Research Communications, 2025, 906-920
-
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
|
|
| S4215 |
Ribostamycin Sulfate
|
Ribostamycin Sulfate(Vistamycin Sulfate,Landamycine) is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidificus.
|
-
PLoS Pathog, 2020, 16;16(3):e1008341
-
Pathogens, 2019, 8(3)
|
|
| S5410 |
Chloramphenicol sodium succinate
|
Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.
|
-
Oncotarget, 2018, 9(40):26086-26095
-
Oncotarget, 2018, 26086-26095
|
|
| S5208 |
Ciprofloxacin hydrochloride hydrate
|
Ciprofloxacin Hydrochloride (Ciloxan, Ceprimax, Oftacilox,Bay-09867 hydrochloride hydrate) is the hydrochloride salt form of ciprofloxacin, which is an antibiotic used to treat a number of bacterial infections.
|
-
Heliyon, 2024, 10(11):e32571
-
Nanomaterials (Basel), 2021, 11(8)1984
|
|
| S4833 |
Cefoxitin sodium
|
Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
|
-
Cancer Research Communications, 2025, 906-920
-
Cancer Res Commun, 2025, 10.1158/2767-9764.CRC-24-0433
|
|
| S4536 |
Nitrofurantoin
|
Nitrofurantoin (Macrodantin, Furadantine, Furadonine) is an antibiotic used to treat bladder infections. It inhibits bacterial DNA, RNA, and cell wall protein synthesis.
|
-
J Clin Med, 2023, 12(16)5166
-
Journal of Clinical Medicine, 2023, 5166
|
|
| S2510 |
Spectinomycin 2HCl
|
Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis.
|
-
Cell Rep, 2020, 32(2):107897
|
|
| S2568 |
Neomycin sulfate
|
Neomycin sulfate(Framycin sulfate) is an aminoglycoside antibiotic, used to treat bacteria infections.
|
-
Mol Cell, 2020, 22 pii: S1097-2765(20)30231-8
|
|
| S4052 |
Netilmicin Sulfate
|
Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.
|
-
J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
|
|
| S2514 |
Tobramycin
|
Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.
|
-
Oncotarget, 2018, 9(40):26086-26095
|
|
| S5051 |
Pipemidic acid
|
Pipemidic acid (Acido pipemidico) is a pyridopyrimidine antibiotic derivative of piromidic acid with activity against gram-negative bacteria including Pseudomonas aeruginosa and some gram-positive bacteria. This compound is an inhibitor of DNA gyrase that is a bacterial enzyme which catalyzes the ATP-dependent negative supercoiling of DNA. It can be used for the research of intestinal, urinary, and biliary tract infections.
|
-
Hum Mol Genet, 2020, ddaa244
|
|
| S2052 |
Oxytetracycline Dihydrate
|
Oxytetracycline Dihydrate is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
|
-
Front Microbiol, 2016, 7:1765
|
|
| S4183 |
Paromomycin Sulfate
|
Paromomycin Sulfate(Aminosidine sulfate) is an aminoglycoside antibiotics inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.
|
-
Biomed Chromatogr, 2022, e5519.
|
|
| S5644 |
Ceftriaxone Sodium
|
Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
|
-
Biosensors (Basel), 2024, 14(3)129
|
|
| S4517 |
Cefotaxime sodium
|
Cefotaxime sodium(HR-756) salt is a third-generation cephalosporin antibiotic; broad-spectrum antibiotic with activity against numerous Gram-positive and Gram-negative bacteria.
|
-
Biosensors (Basel), 2024, 14(3)129
|
|
| S1370 |
Biapenem
|
Biapenem (L-627, LJC10627) is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
|
|
|
| S1768 |
Cefditoren Pivoxil
|
Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria.
|
|
|
| S1998 |
D-Cycloserine
|
D-cycloserine (RO-1-9213) is an analog of the amino acid D-alanine, used as an antibiotic in the treatment of tuberculosis.
|
|
|
| S2544 |
Cefprozil hydrate
|
Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
|
|
|
| S2563 |
Oxacillin sodium monohydrate
|
Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
|
|
|
| S1915 |
Sulfamethoxazole
|
Sulfamethoxazole(Ro 4-2130) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM.
|
|
|
| S2543 |
Ceftiofur HCl
|
Ceftiofur HCl (U-67279A,Excenel hydrochloride) is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
|
|
|
| S3162 |
Tylosin tartrate
|
Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
|
|
|
| S3179 |
Carbenicillin disodium
|
Carbenicillin (BRL-2064,α-carboxybenzylpenicillin) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
|
|
|
| S3193 |
Ticarcillin sodium
|
Ticarcillin (AB 2288, BRL 2288) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
|
|
|
| S5227 |
Erythromycin thiocyanate
|
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
|
|
|
| S5560 |
Midecamycin
|
Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
|
|
|
| S5048 |
Fosfomycin Disodium
|
Fosfomycin (Phosphonemycin) is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an early stage in cell wall synthesis.
|
|
|
| S5353 |
Cefpiramide sodium
|
Cefpiramide sodium (CPMS, SM-1652,wy-44635) is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
|
|
|
| S5951 |
Cefoxitin
|
Cefoxitin is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
|
|
|
| S4850 |
Flucloxacillin sodium
|
Flucloxacillin sodium (Floxacillin sodium) is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
|
|
|
| S4594 |
Cephalothin sodium
|
Cephalothin (Cefalotin, Cephalotin) sodium is a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
|
|
|
| S5941 |
Besifloxacin
|
Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis.
|
|
|
| S5278 |
Tedizolid
|
Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
|
|
|
| S4869 |
Sulfamethoxazole sodium
|
Sulfamethoxazole sodium is an antibiotic used for bacterial infections.
|
|
|
| S4595 |
Cefazolin Sodium
|
Cefazolin Sodium (cefazoline, cephazolin, Ancef) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
|
|
|
| S5936 |
Cefazolin
|
Cefazolin(Cephazolin) is a semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
|
|
|
| S4596 |
Cefixime
|
Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
|
|
|
| S4156 |
Chlortetracycline HCl (NSC 13252)
|
Chlortetracycline HCl (NSC 13252, 7-Chlorotetracycline, Aureomycin monohydrochloride) was the first identified tetracycline antibiotic.
|
|
|
| S5296 |
Cephradine monohydrate
|
Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
|
|
|
| S5487 |
Cefoperazone sodium
|
Cefoperazone Sodium(CP 52640-2) is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
|
|
|
| S5736 |
Benzathine penicilline
|
Benzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
|
|
|
| S1884 |
Sparfloxacin
|
Sparfloxacin (AT-4140, CI-978, PD 131501,Zagam) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
|
|
|
| S2385 |
Hordenine
|
Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
|
|
|
| S5417 |
Spectinomycin dihydrochloride pentahydrate
|
Spectinomycin dihydrochloride pentahydrate (Trobicin) is a widely used antibiotic that inhibits bacterial protein synthesis by blocking translocation of messenger RNA and transfer RNAs on the ribosome.
|
|
|
| S4179 |
Mezlocillin Sodium
|
Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms.
|
|
|
| S4060 |
Erythromycin Ethylsuccinate
|
Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
|
|
|
| S5515 |
Penicillin G Procaine
|
Procaine benzylpenicillin (Procaine benzylpenicillin,PGP), also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
|
|
|
| S5637 |
Cefotiam Hexetil Hydrochloride
|
Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
|
|
|
| S5295 |
Lincomycin Hydrochloride Monohydrate
|
Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
|
|
|
| S8871 |
Omadacycline tosylate
|
Omadacycline tosylate(PTK 0796 tosylate,Amadacycline tosylate) is a first-in-class aminomethylcycline antibiotic, demonstrating antimicrobial activity in vitro against a range of Gram-positive and Gram-negative aerobes and some anaerobic bacteria.
|
|
|
| S5420 |
Clindamycin alcoholate
|
Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
|
|
|
| S4750 |
Sulfacetamide sodium salt hydrate
|
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase(DHPS) with IC50 of 9.5 μM. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid.
|
|
|
| S3636 |
Cefadroxil hydrate
|
Cefadroxil(BL-S 578 hydrate) is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
|
|
|
| S3708 |
Sulfachloropyridazine
|
Sulfachloropyridazine is an antibiotic used to treat a variety of bacterial infections.
|
|
|
| S4663 |
Fusidate Sodium
|
Fusidate Sodium (Fucidin, SQ-16360) is a sodium salt form of fusidic acid, a bacteriostatic antibiotic derived from the fungus Fusidium coccineum and used as a topical medication to treat skin infections.
|
|
|
| S4271 |
Isepamicin Sulphate
|
Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) is an aminoglycoside antibiotic, which inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
|
|
|
| S3672 |
Cefonicid sodium
|
Cefonicid sodium (Monocid) is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
|
|
|
| S4213 |
Dirithromycin
|
Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.
|
|
|
| S5070 |
Mupirocin calcium
|
Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.
|
|
|
| S3650 |
Penicillin V potassium salt
|
Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
|
|
|
| S4523 |
Dihydrostreptomycin sulfate
|
Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep. Dihydrostreptomycin is a derivative of streptomycin.
|
|
|
| S5473 |
Pivmecillinam hydrochloride
|
Pivmecillinam is a β-lactam antibiotic and a prodrug of mecillinam. It has selective activity against Gram-negative bacteria and is used primarily in the treatment of lower urinary tract infections.
|
|
|
| S5350 |
Cefpodoxime proxetil
|
Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
|
|
|
| S4813 |
Cefuroxime axetil
|
Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
|
|
|
| S4393 |
Cephapirin Sodium
|
Cephapirin Sodium (Cefapirin) is the sodium salt form of cephapirin, a semi-synthetic, first-generation cephalosporin antibiotic with bactericidal activity. This compound is effective against gram-negative and gram-positive organisms.
|
|
|