Thymidine (NSC 21548)

For research use only.

Catalog No.S4803 Synonyms: Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd

2 publications

Thymidine (NSC 21548) Chemical Structure

CAS No. 50-89-5

Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd, NSC 21548) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix.

Selleck's Thymidine (NSC 21548) has been cited by 2 publications

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Biological Activity

Description Thymidine (Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd, NSC 21548) is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix.
Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Vero NETLdFVCdnSrdnnyZYwh[XO|YYm= MULBcpRqNUincoDld{B{cW2ybHX4JJZqenW|IIT5dIUuOSCjY4Tpeol1gSCrbjD2[ZJwKGOnbHzzJJV{cW6pIIDsZZF2\SCrbnjpZol1cW:wIHHzd4F6NCCLQ{WwJF0hOC5yMECzJO69VS5? NEDnNVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMES2OFAyPyd-MUC0OlQxOTd:L3G+
HepG2.2.15 MoSwRY51cX[rcnHsJIF{e2G7 M1zWXGFvfGm4aYLhcEBi[3Srdnn0fUBi\2GrboP0JGhDXiCrbjDI[ZBIOi5{LkG1JINmdGy|IHHzd4V{e2WmIHHzJIRm[3KnYYPlJIlvKGW6dILhZ4VtdHWuYYKgeolz[WxiRF7BJIxmfmWuIHL5JHJVNVCFUjygSWM2OCB;IECuN{DPxE1w M4nEZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEC0NFA3Lz5zN{SwOFAxPjxxYU6=
HL-60 M{KwOWZ2dmO2aX;uJIF{e2G7 MWfUbIUh[2:vcH;1coQhf2G|IITld5Rm\CCob4KgX|NJZVSmUjDpcoNwenCxcnH0bY9vKGmwdH:gSG5CKGmwIFjMMVYxKGOnbHzzMEBKTDVyIE2gNE43OSEQvF2u M1L6O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEC1NFMoRjJ6NEC1NFM9N2F-
Vero MUnGeY5kfGmxbjDhd5NigQ>? M2HyUmNwdXCxdX7kJJdieyCndnHseYF1\WRiZn;yJGtqdmW2aXOgZ49ve3SjboSg[o9zKGOnbHz1cIFzKHSqeX3p[Ilv\SCtaX7hd4UhcW5iVnXyc{Bk\WyuczygT40hRSByLkixJO69VS5? Mmr5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB|M{K0OEc,OzB|M{K0OFww[T5?
HEL MkXlRY51cX[rcnHsJIF{e2G7 M3HtTlMh\GG7cx?= M3fVOmFvfGm4aYLhcEBi[3Srdnn0fUBi\2GrboP0JGh2dWGwIHHk[Y5wfmm{dYOgNkBqdm[nY4Tl[EBqdiCqdX3hckBJTUxiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kB3cXK3cz3pcoR2[2WmIHP5eI9x[XSqaXOg[YZn\WO2IHHmeIVzKDNiZHH5d{BjgSCvaXPyc5Nkd3CrYzDt[ZRpd2RuIFXDOVAhRSB{MjFOwG0v M1;nS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMki2PVUzLz5|MEK4Olk2OjxxYU6=
ONS M3n3b2Z2dmO2aX;uJIF{e2G7 M2Ttd|ExKHWP M2PXVFI1KGi{cx?= MoHNTY5lfWO2aX;uJI9nKHCqZX7veJlxcWNicHXyeJVz[mG2aX;uJIlvKGi3bXHuJG9PWyClZXzsd{Bie3Onc4Pl[EBieyCmZXPy[YF{\SCrbjDFSWEyNWG|c3;jbYF1\WRiZXHycJkh\W6mb4PvcYV{KGyndnXsJIlvKGG2IEGwJJVOKGGodHXyJFI1KGi{czDifUBGTUFzIIP0ZYlvcW6pIHLhd4VlKGG|c3H5JJJmdGG2aY\lJJRwKGOxboTyc4w> MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjh6M{S3NEc,OjZ6OEO0O|A9N2F-
ONS M{TxdmZ2dmO2aX;uJIF{e2G7 MV[xNEB2VQ>? NV:zeFhHOjRiaILz M2Xre2lv\HWldHnvckBw\iCyaHXuc5R6eGmlIIDldpR2emKjdHnvckBqdiCqdX3hckBQVlNiY3XscJMh[XO|ZYPz[YQh[XNiZHXjdoVie2ViaX6gZZV1d3CqYXf5JI1iemuncoOgcIV3\WxiaX6gZZQhOTBidV2gZYZ1\XJiMkSgbJJ{KHKnbHH0bZZmKHSxIHPvcpRzd2x? NEDNeI89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nki4N|Q4OCd-Mk[4PFM1PzB:L3G+

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Protocol

References

Solubility (25°C)

In vitro DMSO 48 mg/mL (198.15 mM)
Ethanol ''-1 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 242.23
Formula

C10H14N2O5

CAS No. 50-89-5
Storage powder
in solvent
Synonyms Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd
Smiles CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O

In vivo Formulation Calculator (Clear solution)

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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The Serial Dilution Calculator Equation

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    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
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Molecular Weight Calculator

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Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01199250 Not yet recruiting Other: Laboratory Biomarker Analysis Lynch Syndrome|Recurrent Uterine Corpus Carcinoma|Stage I Uterine Corpus Cancer|Stage II Uterine Corpus Cancer|Stage III Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer Gynecologic Oncology Group|National Cancer Institute (NCI)|GOG Foundation January 2100 --
NCT02861183 Not yet recruiting Device: OVT (Sodium Hyaluronate)|Device: Saline Epicondylitis|Tennis Elbow|Epicondylosis Anika Therapeutics Inc. September 2025 Not Applicable
NCT02442752 Withdrawn Drug: Dexlansoprazole Pediatric Gastroesophageal Reflux Disease Takeda June 15 2025 Phase 1
NCT04900025 Not yet recruiting Other: Bright lighting|Other: Placebo lighting Daytime Cognitive Performance|Sleep|Alertness University of Wisconsin Madison June 2024 Not Applicable
NCT01341548 Not yet recruiting Drug: Civamide nasal solution 0.01% Episodic Cluster Headache Winston Laboratories November 2023 Phase 3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID