Home DNA Damage/DNA Repair -Cell Cycle DNA/RNA Synthesis ribonucleotide-reductase Selective Inhibitors
  • tRNA synthetase
  • RdRp
  • DNA synthesis
  • helicase
  • ribonucleotide reductase

ribonucleotide-reductase Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1218 Clofarabine Clofarabine (Clolar) inhibits the enzymatic activities of ribonucleotide reductase (RNR) (IC50 = 65 nM) and DNA polymerase. Clofarabine induces autophagy and apoptosis. Selective Ribonucleotide reductase, IC50: 65 nM
S7470 Triapine (3-AP) Triapine (3-AP) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity by inhibiting DNA synthesis. Phase 2. Selective