Estrogen receptor Selective Agonists | Antagonists | Chemicals | Modulators

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S2473 Hexestrol

Hexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.

Selective ERα, EC50: 0.07 nM; ERβ, EC50: 0.175 nM
S1191 Fulvestrant

Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM.

Selective ER, IC50: 0.94 nM
S1227 Raloxifene HCl

Raloxifene is an estrogen antagonist, which inhibits human cytosolic aldehyde oxidase-catalyzed phthalazine oxidation activity with IC50 of 5.7 nM.

Selective ER, IC50: 5.7 nM
S2128 Bazedoxifene HCl

Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM, respectively.

Selective ERβ, IC50: 89 nM; ERα, IC50: 23 nM
S1776 Toremifene Citrate

Toremifene Citrate is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer.

S1238 Tamoxifen

Tamoxifen is an antagonist of the estrogen receptor in breast tissue.

S2450 Equol

Equol ,a metabolite of soybeans, is an important isoflavone in humans,specifically binds to 5α-DHT, has a modest affinity for recombinant estrogen receptor ERβ. Phase 2.

S1709 Estradiol

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone.

S4046 Estradiol Cypionate

Estradiol cypionate is the 17 β-cyclopentylpropinate ester of estradiol, which inhibits ET-1 synthesis via estrogen receptor.

S1859 Diethylstilbestrol

Diethylstilbestrol, a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.

S2832 Epiandrosterone

Epiandrosterone is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA.

S2561 Clomifene citrate

Clomifene Citrate is a selective estrogen receptor modulator, used in the treatment of ovulation induction.

S2167 Bazedoxifene Acetate

Bazedoxifene Acetate is a third generation selective estrogen receptor modulator (SERM).

S2466 Estriol

Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

S4285 Ospemifene

Ospemifene is a non-hormonal selective estrogen receptor modulator (SERM), used for the treatment of dyspareunia.

S1972 Tamoxifen Citrate

Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding.

S1665 Estrone

Estrone is an estrogenic hormone.

S1625 Ethinyl Estradiol

Ethinyl Estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.

S3149 Estradiol valerate

Estradiol is a synthetic ester used to treat menopausal symptoms and hormone deficiencies.