Tamoxifen

Catalog No.S1238 Synonyms: ICI 46474

Tamoxifen Chemical Structure

Molecular Weight(MW): 371.51

Tamoxifen is an antagonist of the estrogen receptor in breast tissue.

Size Price Stock Quantity  
USD 147 In stock
USD 297 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Cited by 4 Publications

1 Customer Review

  • E, Analysis of BrCSC viability upon treatment with tamoxifen (tam) and fulvestrant (fulv) at the indicated doses. The experiments were performed in triplicates. ** P<0.01.

    Oncotarget, 2015, 6(4):2315-30.. Tamoxifen purchased from Selleck.

Purity & Quality Control

Choose Selective Estrogen/progestogen Receptor Inhibitors

Biological Activity

Description Tamoxifen is an antagonist of the estrogen receptor in breast tissue.
Targets
estrogen receptor [1]
In vitro

TAM treatment inhibits significantly MCF7 cell proliferation. Low doses of TAM are able to induce structural chromosomal aberrations (deletions, isochromosomes, translocations, and dicentric chromosomes) in both ER+ and ER- breast cancer cells. This genotoxic effect is higher in those cell lines with HER2 gene amplification[2]. Whereas TAM at lower concentrations (0.1-1 μM) induces a cell-cycle arrest, pharmacological concentrations (above 5 μM) of TAM have been found to induce apoptosis of breast cancer cells. 5 μM TAM rapidly induced sustained activation of ERK1/2 in ER-positive breast cancer cell lines (MCF-7 and T47D)[3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
MCF7 cells M2fJPGZ2dmO2aX;uJIF{e2G7 MkO3SYZn\WO2aY\lJINwdmOnboTyZZRqd25iYXfhbY5{fCCPQ1[tO{BjemWjc4SgeJVud3JiY3XscJMhfXOrbnegUWNHNTdiYYPzZZktKEWFNUC9NE4xOSEQvF2= NVPHfnV2OTJ6MkW5N|U>
MCF7 cells M1zT[WN6fG:2b4jpZ4l1gSCjc4PhfS=> M1OzflQ5KGh? MY\DfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDNR2Y4KGOnbHzzJIFnfGW{IES4JIhzeyCkeTDTVmIh[XO|YYmsJGlEPTB;MD6wNlch|ryP MoP4NlI1PzJyNEW=
Ishikawa cells NVzCb4lmTnWwY4Tpc44h[XO|YYm= M4rnO2NwdmOnboTyZZRqd25ib3[gZ49ueG:3bnSgdoVyfWm{ZXSgeI8hcW6mdXPlJFUxKCVib3[geIhmKG2jeHnteY0he3SrbYXsZZRqd25ib3[gZYxs[WyrbnWgdIhwe3CqYYThd4Uh[WO2aY\peJkhcW5iSYPobYtif2FiY3XscJMtKEWFNUC9NE4xOzNizszN NWS2VpZOQDJyMUW4Oy=>
HEK293T cells NW\F[nM2TnWwY4Tpc44h[XO|YYm= M2LjPWFvfGGpb37pd5Qh[WO2aY\peJkh[XRiR3HsOEBFSkRvZoXz[YQhcHWvYX6gSXJidHCqYTDMRmQh\XiycnXzd4VlKGmwIFjFT|I6O1RiY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBme3S{YXTpc4wucW6mdXPl[EB1emGwc3PybZB1cW:wYXygZYN1cX[jdHnvckBi\nSncjCyNEBpenNiYomgcJVkcW[ncnHz[UBz\XCxcoTldkBo\W6nIHHzd4F6NCCLQ{WwQVAvODN7IN88US=> Mn3TNlM4QDZ2NUK=
MDA-MB-435 cells M2\BOWZ2dmO2aX;uJIF{e2G7 MUPJcohq[mm2aX;uJI9nKE2GQT3NRk01OzViYoLlZZN1KGOjbnPldkBk\WyuIIDyc4xq\mW{YYTpc44tKEmFNUC9NE4xPSEQvF2= M2HvSVE1QTdzOEm5
MDA-MB-231 cells NI\ne2pHfW6ldHnvckBie3OjeR?= MmP4TY5pcWKrdHnvckBw\iCnc4Tyc4dmdiC{ZXPldJRweiCwZXfheIl3\SCPRFGtUWIuOjNzIHLy[YF{fCClYX7j[ZIh[2WubDDwdo9tcW[ncnH0bY9vNCCLQ{WwQVAvODhizszN NV\1[YZXOTR7N{G4PVk>
T47D cells MUfGeY5kfGmxbjDhd5NigQ>? NXjqWXlOSW62aXXzeJJw\2WwaXOgZYN1cX[rdImgbY4hcHWvYX6gWFQ4TCClZXzsd{BmgHC{ZYPzbY5oKGW|dILv[4VvKHKnY3XweI9zKGG|c3Xzd4VlKGG|IHXzeJJw\2WwLXTldIVv\GWwdDD0doFve2O{aYD0bY9vKGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhUUN3ME2wMlEh|ryP NHTGTGcyQTF|MUK0PC=>
Ishikawa cells MUPGeY5kfGmxbjDhd5NigQ>? MoPLO|IhcA>? NXyyRm01SW62aXXzeJJw\2WwaXOgZYN1cX[rdImgbY4hcHWvYX6gTZNpcWujd3GgZ4VtdHNiYYPz[ZN{\WRiYYOgbY5pcWKrdHnvckBw\iCnc4Tyc4dmdi2rbnT1Z4VlKGGua3HsbY5mKHCqb4PwbIF1[XOnIHHjeIl3cXS7IHHmeIVzKDd{IHjyd{whUUN3ME2wMlE4KM7:TR?= M1[xSFE5QDN3MUe2
MCF-7-2a cells NFn5dpJHfW6ldHnvckBie3OjeR?= M{\uV2FvfGmnc4Tyc4dmdmmlIHHjeIl3cXS7IHnuJG1ETi15LULhJINmdGy|IHHzJINwdmOnboTyZZRqd25icnXxeYlz\WRidH:gdoVlfWOnIHXzeJJi\GmxbDDl[oZm[3RiYomgOVAmNCCLQ{WwQVAvPSEQvF2= MXqxNlQ{OTB4Mx?=
EL4 cell NWPkUlRCWHKxbHnm[ZJifGmxbjDhd5NigQ>? M{Hqe2lvcGmkaYTpc44hd2ZiW{PIYZRpgW2rZHnu[UBqdmOxcoDvdoF1cW:wIHnueI8hTUx2IHPlcIwheHKxbHnm[ZJifGmxbjygbYM2OD1yLkWzOUDPxE1? NYLwUXA4OTV5M{[zNC=>
HeLa cells MUjGeY5kfGmxbjDhd5NigQ>? M2fXU2lvcGmkaYTpc44hd2ZiMUetZoV1[S2nc4TyZYRqd2xibXXkbYF1\WRibIXjbYZmemG|ZTD0doFve2O{aYD0bY9vKGmwIFjlUIEh[2WubIOg[ZhxemW|c3nu[{BpfW2jbjDld5Rzd2enbjDy[YNmeHSxcjDhcJBp[TtiRWLFJIF{e2G7LDDJR|UxRTBwNkKyJO69VQ>? NWrNeFNQOTV4NUi4OVE>
MDA-MB-231 cells NVH5e5BJWHKxbHnm[ZJifGmxbjDhd5NigQ>? NXXnNmR5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDNSGEuVUJvMkOxJINmdGy|IHL5JG1VXCCjc4PhfUwhUUN3ME2wMlY3KM7:TR?= M4D1OlIxPDVzM{iw
T47D cells MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGDkSVc4OiCq NVXxUY5{T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4h\XO2cn;n[Y4u\GWyZX7k[Y51KFR2N1SgZ4VtdHNiYX\0[ZIhPzJiaILzMEBKSzVyPUGg{txO Mm\RNVkyOzF{NEi=
yeast AH109 cells NIXqUGdHfW6ldHnvckBie3OjeR?= M3jxRVI1KGh? M2e1cWFvfGGpb37pd5Qh[WO2aY\peJkh[XRiRWLi[ZRiKHKnY3XweI9zKEyERDDlfJBz\XO|ZXSgbY4hgWWjc4SgRWgyODliY3XscJMh[XO|ZYPz[YQh[XNiaX7obYJqfGmxbjDv[kBqdnSncnHjeIlwdiC5aYToJHNTSzFiYX\0[ZIhOjRiaILzJIJ6KGGucHjhMYdidGGldH;zbYRie2ViYYPzZZktKEmFNUC9NU43PiEQvF2= NFLySYwzOjZ2N{KxOy=>
GBM2 cells NVzYRWM{WHKxbHnm[ZJifGmxbjDhd5NigQ>? M3:wUlczKGh? NGi5S4pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFfCUVIh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGmwY4XiZZRm\CCob4KgO|IhcHK|IHL5JHdUXC1zIH3leIhw\CxiSVO1NF0{NjVizszN MXKyOlM2PTV|Mh?=
NCI-H460 cells M1;r[mZ2dmO2aX;uJIF{e2G7 NYHNVldDOjRiaB?= MYTBcpRq[2GwY3XyJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iTlPJMWg1PjBiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JHNTSiCjc4PhfUwhUUN3ME20MlQ5KM7:TR?= NFrVb4QyQTd|M{C4OS=>
GBM3 cells Mnz2VJJwdGmoZYLheIlwdiCjc4PhfS=> M3rkUlczKGh? NFqzOWtCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFfCUVMh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIHPlcIwhfmmjYnnsbZR6KGmwY4XiZZRm\CCob4KgO|IhcHK|IHL5JHdUXC1zIH3leIhw\CxiSVO1NF01NjdizszN MknhNlY{PTV3M{K=
DLD1 cells MmS0R5l1d3SxeHnjbZR6KGG|c3H5 M3;xVlk3KGh? NV[4e4RJS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hTEyGMTDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwQVQvPzhizszN NXP4[WpyOjJ5NEmzPVI>
ScN2a-cl3 cells M3K1bGN6fG:2b4jpZ4l1gSCjc4PhfS=> Mlr6OUBl[Xm| MVnDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDkbZZq\GmwZzDTZ24z[S2lbEOgZ4VtdHNiYYPz[ZN{\WRiYYOgZ4VtdCC4aXHibYxqfHliYX\0[ZIhPSCmYYnzJIJ6KGOjbHPlbY4uSU1ic4ThbY5qdmdvYnHz[YQh\my3b4Lld4NmdmOnIHHzd4F6NCCLQ{WwQVQvQDlizszN NWfrUlJUOjRzOEO1PFk>
K562 cells MVjQdo9tcW[ncnH0bY9vKGG|c3H5 NHnINHg4OiCq MU\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEt3NkKgZ4VtdHNiYX\0[ZIhPzJiaILzMEBKSzVyPUWuNkDPxE1? NGPrNWkzPTR{MEG3OS=>
MDA-MB-435S cells MVzDfZRwfG:6aXPpeJkh[XO|YYm= MlnzR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUWRCNU2ELUSzOXMh[2WubIOgZZN{\XO|ZXSgZZMh[2WubDD2bYFjcWyrdImgZpkhVVSWIHHzd4F6NCCLQ{WwQVUvPSEQvF2= NF7zWHgzPjB5OUC5NC=>
DU145 cells NFvrc5pRem:uaX\ldoF1cW:wIHHzd4F6 MnzoOFghcA>? M2\pNmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iRGWxOFUh[2WubIOgZYZ1\XJiNEigbJJ{KGK7IF3UWEBie3OjeTygTWM2OD13LkWg{txO NF\w[2EzOzJ6N{C1Oy=>
HepG2 cells MXXQdo9tcW[ncnH0bY9vKGG|c3H5 NVzYfJIyPDhiaB?= NGm2[4tCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIFjldGczKGOnbHzzJIFnfGW{IES4JIhzeyCkeTDNWHQh[XO|YYmsJGlEPTB;Nj6zJO69VQ>? Mlz2NlMzQDdyNUe=
SKOV3 cells M{nqfWZ2dmO2aX;uJIF{e2G7 NHzVZWszPCCq M2\2[WFvfGmlYX7j[ZIh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDTT29XOyClZXzsd{Bi\nSncjCyOEBpenNiYomgV3JDKGG|c3H5MEBKSzVyPU[uOEDPxE1? M2n6O|E6PzN|MEi1
PC3 cells MUDQdo9tcW[ncnH0bY9vKGG|c3H5 M2fwfFI1KGh? NVHxUGFuSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDQR|Mh[2WubIOgZYZ1\XJiMkSgbJJ{KGK7IF3UWEBie3OjeTygTWM2OD15IN88US=> M2\teFI1QDhyMkOw
NIH/3T3 cells MXjDfZRwfG:6aXPpeJkh[XO|YYm= MV[5OkBp NXG0bndzS3m2b4TvfIlkcXS7IHHnZYlve3RibX;1d4UhVkmKL{PUN{Bk\WyuczDh[pRmeiB7NjDodpMh[nliU2LCJIF{e2G7LDDJR|UxRTdwMk[g{txO NEjUNYczOjd2OUO5Ni=>
GBM1 cells NUj2bo12WHKxbHnm[ZJifGmxbjDhd5NigQ>? MUe3NkBp MUjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEeETUGgZ4VtdHNiYYPz[ZN{\WRiYYOgdoVlfWO2aX;uJIlvKGOnbHygeoli[mmuaYT5JIlv[3WkYYTl[EBnd3JiN{KgbJJ{KGK7IGfTWE0yKG2ndHjv[EwhUUN3ME23MlUh|ryP NXWxNXBKOjZ|NUW1N|I>
518A2 cells NH71SZpEgXSxdH;4bYNqfHliYYPzZZk> NVvUNY5CQTZiaB?= NW\wWndmS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hPTF6QUKgZ4VtdHNiYX\0[ZIhQTZiaILzJIJ6KFOUQjDhd5NigSxiSVO1NF04NjZ{IN88US=> M{DLfVIzPzR7M{my
A2780 cells Mmf4R5l1d3SxeHnjbZR6KGG|c3H5 NG\FUG86PiCq M4rt[mN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGEzPzhyIHPlcIx{KGGodHXyJFk3KGi{czDifUBUWkJiYYPzZZktKEmFNUC9O{44PyEQvF2= Mn:2NlI4PDl|OUK=
A549 cells M{nFdWN6fG:2b4jpZ4l1gSCjc4PhfS=> NHHMXXNEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGG|c3Xzd4VlKGG|IHPlcIwhfmmjYnnsbZR6KGK7IF3UWEBie3OjeTygTWM2OD16LkSg{txO NFjlTmQzPjB5OUC5NC=>
Lipo cells NWD0Zo9mS3m2b4TvfIlkcXS7IHHzd4F6 MXq5OkBp Mm\4R5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gUIlxdyClZXzsd{Bi\nSncjC5OkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUiuOlQh|ryP MlrvNlI4PDl|OUK=
A253 cells NHjUV2FEgXSxdH;4bYNqfHliYYPzZZk> NUnRSnNmQTZiaB?= NXW3WJJbS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hSTJ3MzDj[YxteyCjZoTldkA6PiCqcoOgZpkhW1KEIHHzd4F6NCCLQ{WwQVgvQTJizszN NYPIXo5JOjJ5NEmzPVI>
HT-29 cells MnfHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUj0dGJYT3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMkmgZ4VtdHNuIFnDOVA:QS53IN88US=> MXOyN|QxOzB6NB?=
LNCAP cells MXrQdo9tcW[ncnH0bY9vKGG|c3H5 Mn7YOFghcA>? MVrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEyQQ1HQJINmdGy|IHX4dJJme3OrbnegZY5lem:pZX6gdoVk\XC2b4KgbY5kfWKjdHXkJJdqfGhiMD62JI5OKG:oIHXzeJJi\GmxbDDhcoQhOC55IH7NJI9nKHSnc4Tvd5Rmem:wZTDh[pRmeiB2ODDodpMh[nlic4Xs[o9zcG:mYX3pcoUhSiCjc4PhfUwhUUN3ME2xNEDPxE1? NXLSb|VEOjF3MUOyO|U>
M21 cells MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUX4WWc1T3Kxd4ToJIlvcGmkaYTpc44hd2ZiaIXtZY4hVTJzIHPlcIx{NCCLQ{WwQVEyKM7:TR?= NF\xU4kzOzRyM{C4OC=>
850C cells Mn:3R5l1d3SxeHnjbZR6KGG|c3H5 M2rxe|k3KGh? M{DDVGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJFg2OENiY3XscJMh[W[2ZYKgPVYhcHK|IHL5JHNTSiCjc4PhfUwhUUN3ME2xNU4xQSEQvF2= M3PT[lIzPzR7M{my
HL60 cells MWfDfZRwfG:6aXPpeJkh[XO|YYm= NYTuWplXPzJiaB?= MnjqR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTGw3OCClZXzsd{Bi\nSncjC3NkBpenNiYomgW3NVOSCjc4PhfUBqdiCycnXz[Y5k\SCxZjCyNEUhTkKVLDDJR|UxRTF2LkOg{txO NXfPRY9QOjJ7MEG4PVU>
MSTO-211H cells NY\5SIxVWHKxbHnm[ZJifGmxbjDhd5NigQ>? M1fHdlczKGh? NIrK[FdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBi\2GrboP0JIh2dWGwIF3TWG8uOjFzSDDj[YxteyCjZoTldkA4OiCqcoOgZpkhfHK7cHHuJIJtfWViYYPzZZktKEmFNUC9NlMvOyEQvF2= M3nReVI{PzN3OEK5
HepG2 cells NUnzeFBtS3m2b4TvfIlkcXS7IHHzd4F6 NWqzTmQ4OjRiaB?= MnnER5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gTIVxTzJiY3XscJMh[W[2ZYKgNlQhcHK|IHL5JGNmdGyWaYTldk1DdHWnQ3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuOO69VQ>? NF\6VZYzODV2NUOzOC=>
KIF5 cells M1rwdWN6fG:2b4jpZ4l1gSCjc4PhfS=> NILoTIUzPCCq NXe4eZczXG:6aXPpeJkh[WejaX7zeEBpfW2jbjDLTWY2KGOnbHzzJIlv[3WkYYTl[EBnd3JiMkSgbJJ{KGK7IFPlcIxVcXSncjDCcJVmKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ|Lke1JO69VQ>? MnLoNlI4PzV2N{S=

... Click to View More Cell Line Experimental Data

In vivo Tamoxifen (TAM) is widely used for both treatment and prevention of breast cancer. However, it is also carcinogenic in human uterus and rat liver[2]. Tm-inducible Cre-loxP systems are being used in broad areas of research and are providing important biologic insights in tissue development, maintenance, and function. Tamoxifen-induced nuclear localization of Cre recombinase is time- and dose-dependent. Higher doses of tamoxifen induce recombination weeks following administration and Lower doses of tamoxifen induce recombination up to one week following administration. Duration of tamoxifen-induced gene recombination is also dose-dependent. Administration of high Tm doses leads to extended CreER nuclear localization. Tm treatment induces side effects that may have physiologic consequences in Tm-inducible models[4].

Protocol

Cell Research:

[2]

+ Expand
  • Cell lines: MCF7 and T47D
  • Concentrations: 10-6 mol/L
  • Incubation Time: 24, 48, and 96 h
  • Method:

    48 h before the addition of E2 and TAM, cells were washed with 5 mL phosphate-buffered saline (PBS) and then switched to phenol red-free RPMI-1640 containing 10% charcoal-stripped FBS. E2 and TAM were dissolved in absolute ethanol and diluted in the media at 10<sup>-8</sup> mol/L and 10<sup>-6</sup> mol/L, respectively, and then added to the culture medium at 24, 48, and 96 h.


    (Only for Reference)
Animal Research:

[4]

+ Expand
  • Animal Models: Pdx1PB-CreERTm mice
  • Formulation: filter-sterilized corn oil
  • Dosages: --
  • Administration: s.c.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 74 mg/mL (199.18 mM)
Ethanol 74 mg/mL (199.18 mM)
Water Insoluble
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
2% DMSO+30% PEG 300+2% Tween 80+ddH2O
For best results, use promptly after mixing.
2mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 371.51
Formula

C26H29NO

CAS No. 10540-29-1
Storage powder
in solvent
Synonyms ICI 46474

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03879174 Not yet recruiting Breast Cancer Female Mediclinic Middle East August 1 2019 Phase 2
NCT03879174 Not yet recruiting Breast Cancer Female Mediclinic Middle East August 1 2019 Phase 2
NCT03879577 Not yet recruiting Breast Cancer|Breast Cancer Female|HER2-positive Breast Cancer|Breast Cancer Stage II|Breast Cancer Stage III University of Chicago April 10 2019 Phase 2
NCT03879577 Not yet recruiting Breast Cancer|Breast Cancer Female|HER2-positive Breast Cancer|Breast Cancer Stage II|Breast Cancer Stage III University of Chicago April 10 2019 Phase 2
NCT03870399 Recruiting Neuroendocrine Tumors|Progesterone Receptor Positive Tumor|Estrogen Receptor Positive Tumor AC Camargo Cancer Center March 13 2019 Phase 2
NCT03870399 Recruiting Neuroendocrine Tumors|Progesterone Receptor Positive Tumor|Estrogen Receptor Positive Tumor AC Camargo Cancer Center March 13 2019 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    Could you tell me if you have a protocol for the use of tamoxifen (S1238) in vivo in mouse? Is there an administration way that is better than another?

  • Answer:

    Tamoxifen (S1238) can be dissolved in 10% ethanol/10% Tween 80/ddH2O at 5 mg/ml clearly. But precipitation will form if the formulation was left at RT for an hour or longer. So we'd suggest that you use it quickly after formulation. Tamoxifen is often administrated via i.p injection.

Estrogen/progestogen Receptor Signaling Pathway Map

Related Estrogen/progestogen Receptor Products0

Tags: buy Tamoxifen | Tamoxifen ic50 | Tamoxifen price | Tamoxifen cost | Tamoxifen solubility dmso | Tamoxifen purchase | Tamoxifen manufacturer | Tamoxifen research buy | Tamoxifen order | Tamoxifen mouse | Tamoxifen chemical structure | Tamoxifen mw | Tamoxifen molecular weight | Tamoxifen datasheet | Tamoxifen supplier | Tamoxifen in vitro | Tamoxifen cell line | Tamoxifen concentration | Tamoxifen nmr
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID