For research use only.
CAS No. 50-50-0
Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.
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|Description||Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ERα with IC50 of 22-28 nM.|
Estradiol benzoate is asynthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol. 
|In vitro||DMSO||75 mg/mL (199.2 mM)|
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|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
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|% DMSO % % Tween 80 % ddH2O|
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