Imiquimod (R-837)

For research use only.

Catalog No.S1211 Synonyms: S-26308

2 publications

Imiquimod (R-837) Chemical Structure

CAS No. 99011-02-6

Imiquimod (R-837, S-26308) is a novel synthetic agent with immune response modifying activity.

Selleck's Imiquimod (R-837) has been cited by 2 publications

Purity & Quality Control

Choose Selective Immunology & Inflammation related Inhibitors

Biological Activity

Description Imiquimod (R-837, S-26308) is a novel synthetic agent with immune response modifying activity.



Solubility (25°C)

In vitro DMSO 1 mg/mL warmed (4.16 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 240.3


CAS No. 99011-02-6
Storage powder
in solvent
Synonyms S-26308
Smiles CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04883645 Recruiting Drug: Imiquimod 5% CreamTopPkt0.25Gm Oral Cancer Columbia University September 2021 Early Phase 1
NCT04642937 Recruiting Drug: Treatment with hP1A8 Glioblastoma OX2 Therapeutics December 1 2020 Phase 1
NCT02301494 Withdrawn Drug: 3.75% Imiquimod Cream|Drug: 0.1% Fluocinonide Cream Mycosis Fungoides Rochester General Hospital|Bausch Health Americas Inc.|Rochester Skin Lymphoma Medical Group PLLC April 2020 Not Applicable
NCT03196180 Active not recruiting Drug: Imiquimod|Drug: Topical Fluorouracil Cervical Intraepithelial Neoplasia Grade 2/3|Cervical Squamous Cell Carcinoma In Situ|Cervical Squamous Intraepithelial Neoplasia 2|High Grade Cervical Intraepithelial Neoplasia National Cancer Institute (NCI) September 30 2019 Early Phase 1
NCT04859361 Active not recruiting Drug: Aldara 5% Topical Cream|Procedure: LLETZ Intraepithelial Neoplasia Cervical University Medical Centre Maribor November 20 2018 Not Applicable

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID