Home Immunology & Inflammation Immunology & Inflammation related chemical Lysionotin

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Lysionotin Immunology & Inflammation related chemical

Cat.No.S3877

Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.
Lysionotin Immunology & Inflammation related chemical Chemical Structure

Chemical Structure

Molecular Weight: 344.32

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S387701 DMSO]68 mg/mL]false]]]false]]]false Purity: 99.89%
99.89

Chemical Information, Storage & Stability

Molecular Weight 344.32 Formula

C18H16O7

 Storage (From the date of receipt)
CAS No. 152743-19-6 Download SDF Storage of Stock Solutions

Synonyms N/A Smiles COC1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)O)OC)O

Solubility

In vitro
Batch:

DMSO : 68 mg/mL (197.49 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

In vitro
Lysionotin is an efficient inhibitor of α-toxin expression and shows significant protection against S. aureus in vitro and in vivo[1].
References

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