Salvianolic acid A

Synonyms: Dan Phenolic Acid A

Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck.

Salvianolic acid A Chemical Structure

Salvianolic acid A Chemical Structure

CAS: 96574-01-5

Selleck's Salvianolic acid A has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.95%
99.95

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Biological Activity

Description Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03908242 Unknown status
Diabetes
Peking University First Hospital
April 8 2019 Phase 1
NCT03791463 Unknown status
Healthy
Peking University First Hospital
December 20 2018 Phase 1
NCT03791125 Unknown status
Neuropathy of Diabetes
Peking University First Hospital|Shandong Huizhi Pharmaceutical Technology Co. Ltd.|Cancer Institute and Hospital Chinese Academy of Medical Sciences
November 20 2018 Phase 1

Chemical Information & Solubility

Molecular Weight 494.45 Formula

C26H22O10

CAS No. 96574-01-5 SDF --
Smiles C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C(C(=C(C=C2)O)O)C=CC3=CC(=C(C=C3)O)O)O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 99 mg/mL ( (200.22 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 99 mg/mL

Ethanol : 99 mg/mL


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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