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Salvianolic acid A Immunology & Inflammation related inhibitor

Name: Salvianolic acid A
Brand: Selleck Chemicals
SKU: S9055
Availability: InStock
Rating: 5 (2 reviews)

Cat.No.S9055

Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck.

Chemical Structure

Molecular Weight: 494.45

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Quality Control

Batch: Purity: 99.84%

99.84

Related Targets	PD-1/PD-L1 CXCR STING AhR CD markers Interleukins Anti-infection Antioxidant COX Histamine Receptor
Other Immunology & Inflammation related Inhibitors	Cl-amidine Bestatin (Ubenimex) Bindarit (AF 2838) Tempol Tranilast GI254023X (GI4023) Sinomenine Geniposidic acid CORM-3 Germacrone

Solubility

In vitro
Batch:

DMSO : 99 mg/mL (200.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 99 mg/mL

Water : 33 mg/mL

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	494.45	Formula	C₂₆H₂₂O₁₀	Storage (From the date of receipt)	3 years-20°C(in the dark) powder
CAS No.	96574-01-5	--		Storage of Stock Solutions	Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

Read more about storage stability CAS number

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2019-04-09)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT03908242	UNKNOWN	Diabetes	Peking University First Hospital	2019-04-08	PHASE1
NCT03908242	Unknown status	Diabetes	Peking University First Hospital	2019-04-08	Phase 1
NCT03791125	UNKNOWN	Neuropathy of Diabetes	Peking University First Hospital	2018-11-20	PHASE1
NCT03791463	UNKNOWN	Healthy	Peking University First Hospital	2018-12-20	PHASE1
NCT03791463	Unknown status	Healthy	Peking University First Hospital	2018-12-20	Phase 1
NCT03791125	Unknown status	Neuropathy of Diabetes	Peking University First Hospital\|Shandong Huizhi Pharmaceutical Technology Co. Ltd.\|Cancer Institute and Hospital Chinese Academy of Medical Sciences	2018-11-20	Phase 1

Tech Support

Handling Instructions

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