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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S1401 Tenofovir Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
J Biomed Sci, 2024, 31(1):34
Hepatol Commun, 2024, 8(1)e0351
Verified customer review of Tenofovir
S1400 Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.
Clin Immunol, 2024, 260:109915
Antiviral Res, 2024, 231:106010
Front Cell Infect Microbiol, 2024, 14:1334126
Verified customer review of Tenofovir Disoproxil Fumarate
S2579 Zidovudine Zidovudine (ZDV, Azidothymidine, NSC 602670) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. This compound could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.
Nat Commun, 2024, 15(1):2716
Nat Commun, 2024, 15(1):9321
J Immunother Cancer, 2024, 12(11)e009805
S1706 Lamivudine (3TC, BCH-189) Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
FASEB J, 2025, 39(12):e70720
HIV Med, 2025, 26(2):285-294
Verified customer review of Lamivudine (3TC, BCH-189)
S7303 Rilpivirine Rilpivirine (R278474, TMC27, DB08864) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.
Nat Chem Biol, 2023, 19(4):431-439
Antimicrob Agents Chemother, 2023, 67(7):e0046223
J Virol, 2022, JVI0173021
S1704 Emtricitabine (FTC) Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor, and its intracellular half-life is 39 h.
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
HIV Med, 2025, 26(2):285-294
Immunity, 2024, 57(12):2928-2944.e6
S5246 Entecavir Entecavir(BMS200475,SQ34676), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
J Virol, 2025, e0010025.
J Biomed Sci, 2024, 31(1):34
NPJ Vaccines, 2024, 9(1):22
S4685 Efavirenz Efavirenz is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.
Front Cell Infect Microbiol, 2024, 14:1334126
Nat Chem Biol, 2023, 19(4):431-439
Antimicrob Agents Chemother, 2023, 67(7):e0046223
S2914 Dapivirine (TMC120) Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. It inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.
J Control Release, 2024, 376:1209-1224
Sci Rep, 2024, 14(1):30103
Pharmaceutics, 2022, 14(9)1938
S1252 Entecavir Hydrate Entecavir Hydrate (ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
Clin Mol Hepatol, 2025, 10.3350/cmh.2024.0694
Cancer Discov, 2022, candisc.1117.2021
Hepatology, 2022, 10.1002/hep.32614

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