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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S1400 Tenofovir Disoproxil Fumarate Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.
Scientific Reports, 2025, 35936
Clin Immunol, 2024, 260:109915
Antiviral Res, 2024, 231:106010
Verified customer review of Tenofovir Disoproxil Fumarate
S1706 Lamivudine (3TC, BCH-189) Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.
Cancer Discovery, May 02 2025, 1063-1082
Frontiers in Cardiovascular Medicine, April 09 2021, 634774
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
Verified customer review of Lamivudine (3TC, BCH-189)
S1401 Tenofovir Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections.
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
J Biomed Sci, 2024, 31(1):34
Hepatol Commun, 2024, 8(1)e0351
Verified customer review of Tenofovir
S2579 Zidovudine Zidovudine (ZDV, Azidothymidine, NSC 602670) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. This compound could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.
Biomolecules, August 6, 2025, 1132
Scientific Reports, April 18, 2018, 6194
Nat Commun, 2024, 15(1):2716
S1704 Emtricitabine (FTC) Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor, and its intracellular half-life is 39 h.
bioRxiv, 2026, nan
Cancer Discov, 2025, 10.1158/2159-8290.CD-24-1317
HIV Med, 2025, 26(2):285-294
S2914 Dapivirine (TMC120) Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. It inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.
Antiviral Research, September 01, 2017, 103-113
PLOS One, June 23, 2015, e0131405
Journal of Cancer, January 01, 2018, 117-128
S5246 Entecavir Entecavir(BMS200475,SQ34676), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
J Virol, 2025, e0010025.
J Biomed Sci, 2024, 31(1):34
NPJ Vaccines, 2024, 9(1):22
S1252 Entecavir Hydrate Entecavir Hydrate (ETV, Baraclude,BMS200475 Hydrate,SQ34676 Hydrate), a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).
Cell Reports, June 7, 2022, 110913
Journal of Virology, July 30, 2019, e00248-19
Viruses, February 21, 2024, 323
S1742 Nevirapine (NSC 641530) Nevirapine (NSC 641530, NVP) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
Neuron, October 19, 2022, 3278-3287.e8
Scientific Reports, October 15, 2025, 15(1)
ACS Infectious Diseases, November 10, 2023, 2105-2118
Verified customer review of Nevirapine (NSC 641530)
S7303 Rilpivirine Rilpivirine (R278474, TMC27, DB08864) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.
Nat Chem Biol, 2023, 19(4):431-439
Antimicrob Agents Chemother, 2023, 67(7):e0046223
J Virol, 2022, JVI0173021

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