Integrin

Isoform-selective Products

Signaling Pathway

Integrin Signaling Pathway

Integrin Products

  • All (46)
  • Integrin Inhibitors (14)
  • Integrin Antibodies (12)
  • Integrin Antagonists (7)
  • Integrin Agonists (2)
  • New Integrin Products
Catalog No. Product Name Information Product Use Citations Product Validations
S7077 Cilengitide trifluoroacetate Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
Int J Mol Sci, 2025, 26(6)2465
Microbiol Spectr, 2025, 13(2):e0222124
iScience, 2024, 27(10):110862
S6387 Cilengitide Cilengitide (EMD 121974, EMD-12192, EMD-85189, NSC-​707544) is a potent and selective inhibitor of the integrins ανβ3 and ανβ5 with IC50 of 4 and 79 nM, respectively.
Nat Commun, 2025, 16(1):2254
NPJ Regen Med, 2024, 9(1):4
World J Gastroenterol, 2024, 30(7):728-741
S7540 SB273005 SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
Cancer Lett, 2024, 582:216597
Nat Commun, 2023, 14(1):3251
Neuron, 2023, S0896-6273(23)00623-2
S8008 RGD (Arg-Gly-Asp) Peptides RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
J Sport Health Sci, 2024, S2095-2546(24)00124-8
iScience, 2024, 27(3):109119
Cell Stem Cell, 2023, 30(6):867-884.e11
S8454 ATN-161 ATN-161 is a novel small peptide antagonist of integrin α5β1. It binds to several integrins, including α5β1 and αvβ3, that play a role in angiogenesis and tumor progression.
Oncol Res, 2025, 33(2):443-464
Nat Commun, 2024, 15(1):5986
Int Immunopharmacol, 2024, 141:112947
S7844 Cyclo(RGDyK) TFA Cyclo(RGDyK) TFA is a salt formed by the combination of Cyclo(RGDyK) and trifluoroacetate (TFA). It is an effective and selective Integrin αvβ3 inhibitor with a low IC50 value (e.g., 20 nM). Cyclo(RGDyK) TFA is of great significance in the treatment of cardiovascular diseases, osteoporosis, inflammation and tumors.
J Clin Invest, 2024, e175147
JBMR Plus, 2024, 8(7):ziae066
Cell Commun Signal, 2023, 10.1186/s12964-022-01027-7
S7834 Cyclo(-RGDfK) TFA Cyclo(-RGDfK) TFA is the salt product of Cyclo(-RGDfK) and trifluoroacetic acid (TFA). The addition of TFA enhances stability and biocompatibility. Cyclo(-RGDfK) TFA effectively targets tumor microvessels and cancer cells by specifically binding to the cell surface Integrin αvβ3.
Pharmaceuticals (Basel), 2025, 18(4)549
Sci Adv, 2024, 10(43):eadp4726
bioRxiv, 2024, 2024.09.17.613509
S8306 Leukadherin-1 Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)).
International Immunopharmacology, 2023, Volume 118
Int Immunopharmacol, 2023, 118:110024
Front Immunol, 2022, 13:919444
S2885 A-205804 A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
Cell Biol Toxicol, 2024, 40(1):90
Stem Cell Res Ther, 2022, 13(1):218
Am J Rhinol Allergy, 2022, 19458924221086061
S3714 Lifitegrast Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.
Med Oncol, 2024, 41(8):188
World J Gastroenterol, 2023, 29(20):3103-3118
World J Gastroenterol, 2023, 29(20):3103-3118
S3085 Tirofiban Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
Food Funct, 2020, 11(1):139-152
S8594 Tirofiban Hydrochloride Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban.
J Immunother Cancer, 2024, 12(11)e009805
Transl Oncol, 2024, 39:101813
Front Cell Infect Microbiol, 2021, 11:783085
S6840 OSU-T315 OSU-T315 (ILK-IN-2) is a potent Integrin-Linked Kinase (ILK) inhibitor with IC50 of 0.6 μM. OSU-T315 induces autophagy and apoptosis, both of which are integral to its antiproliferative activity. OSU-T315 exhibits anti-tumor activity.
Exp Eye Res, 2023, 234:109609
F0362New Slug Rabbit mAb
F0996 Integrin αV Rabbit mAb Integrin alpha V,Integrin αV,Integrin αV/ITGAV
F0632New Integrin β5 Rabbit mAb Integrin beta 5,Integrin β5
F0949New Integrin α5 Rabbit mAb Integrin alpha 5,Integrin alpha5,Integrin alphaV,Integrin α5
F0437New Integrin 3 Rabbit mAb CD61,CD61 (Integrin beta 3),Integrin beta 3,Integrin beta3,Integrin β3,Integrin β3/ITGB3/CD61
F1694New Integrin α2 Rabbit mAb Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12
F1452New Integrin β4 Rabbit mAb Integrin beta 4,Integrin beta4,Integrin β4
F0577New ILK1 Rabbit mAb ILK,ILK1,Integrin linked ILK
F1314New Talin-1 Rabbit mAb Neutrophil,Talin,Talin 1,Talin-1
F1640New Dysferlin Rabbit mAb
F2411New Keratin 12/K12 Rabbit mAb
E0462 Pyrintegrin Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival, also enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling.
Signal Transduct Target Ther, 2024, 9(1):109
Signal Transduct Target Ther, 2024, 9(1):109
A2420 Anti-Integrin b1 / ITGB1 / CD29 Anti-Integrin b1 / ITGB1 / CD29 is a humanized monoclonal antibody directed against the human integrin receptor beta-1 subunit (CD29), with potential antineoplastic activity. MW: 145.5 kD.
A2873 Anti-ICAM3 / CD50 Anti-ICAM3 / CD50 is an IgG1 monoclonal antibody against intercellular adhesion molecules-3 (ICAM-3, also known as CD50)) with the potential to have anti-proliferative activities. MW: 145.22 KD.
E1558New GSK-3008348 HCl GSK-3008348 HCl is a small molecule antagonist of integrin αvβ6 with an affinity (pIC50) value of 8.1 for αvβ6 in cell Adhesion assays.
S0314 TR-14035 TR-14035 (SB 683698, MDK-1191) is a a dual alpha4beta (α4β) integrin antagonist with IC50 of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively.
E4615New GLPG0187 GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity.
Sci Rep, 2025, 15(1):9147
A2464 Bersanlimab (Anti-ICAM1 / CD54) Bersanlimab (Anti-ICAM1 / CD54) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects. MW: 145.5 KD.
S4513 RGD peptide (GRGDNP) RGD peptide (GRGDNP) is an inhibitor of binding of integrins to the extracellular matrixs. RGD peptide (GRGDNP) induces apoptosis presumably through direct activation of caspase-3.
Tradit Med Res, 2023, 8(9):50
E0790 ILK-IN-3 ILK-IN-3 is an integrin linked kinase (ILK) inhibitor with antitumor activity.
E7334New Cyclo(RGDyK) Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis.
A2704 Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100) Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100) is a humanized monoclonal antibody directed against the alpha v beta 6 (αvβ6) integrin. It has a potential to be used in research on Idiopathic Pulmonary Fibrosis (IPF). MW : 144.88 kD.
A2712 Erlizumab (Anti-Integrin b2 / ITGB2 / CD18) Erlizumab (anti-Integrin b2 / ITGB2 / CD18) is a humanized monoclonal antibody targeted against Integrin beta-2 and used as a therapy for hemorrhagic shock. MW: 146.66 kD.
A2988 Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) is a monoclonal antibody targeting the α2 subunit (CD49b) of very late antigen-2 (VLA-2). It can be used for the research of multiple sclerosis. MW: 144.56 KD.
A2990 Intetumumab (Anti-Integrin aV / ITGAV / CD51) Intetumumab (Anti-Integrin aV / ITGAV / CD51) is a potent monoclonal antibody targeting αV-integrins. It can be used in research of uterine serous papillary carcinoma (USPC) treatment. MW :145.58 KD.
A2991 Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD.
A2744 Abituzumab (Anti-Integrin aV / ITGAV / CD51) Abituzumab (Anti-Integrin aV / ITGAV / CD51) is a humanized monoclonal antibody directed against the human alpha v integrin subunit with potential antiangiogenic and antineoplastic activities.MW: 144.78 kD.
A2745 Anti-Integrin a11 / ITAG11 Anti-Integrin a11 / ITAG11 is a monoclonal antibody against Integrin alpha 11 (ITGA11), a transmembrane glycoprotein expressed in adult cardiac and uterine smooth muscle and developing myocytes. MW: 145.7 KD.
E7759New GRGDSP GRGDSP is a fibronectin-derived peptide and an inhibitor of Integrin. It can be used for surface modification of cardiovascular implants, such as vascular grafts, to promote endothelialization, and also holds potential for hepatocellular carcinoma (HCC) treatment by inhibiting tumor cell adhesion and limiting metastasis.
A2761 Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) is a fully human monoclonal immunoglobulin G2 antibody that targets the alpha4beta7 integrin and prevents interaction with MADCAM-1. It has the potential to be used in research on inflammatory bowel disease (IBD). MW: 143.8 kD.
E1385 Bexotegrast Bexotegrast(PLN-74809) is potent dual selective inhibitor of αvβ6 and αvβ1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-β activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).
S3408 A286982 A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively.
A2045 Vedolizumab (anti-α4β7-integrin) Vedolizumab (anti-α4β7-integrin) is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
S7077 Cilengitide trifluoroacetate Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
Int J Mol Sci, 2025, 26(6)2465
Microbiol Spectr, 2025, 13(2):e0222124
iScience, 2024, 27(10):110862
S6387 Cilengitide Cilengitide (EMD 121974, EMD-12192, EMD-85189, NSC-​707544) is a potent and selective inhibitor of the integrins ανβ3 and ανβ5 with IC50 of 4 and 79 nM, respectively.
Nat Commun, 2025, 16(1):2254
NPJ Regen Med, 2024, 9(1):4
World J Gastroenterol, 2024, 30(7):728-741
S7540 SB273005 SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
Cancer Lett, 2024, 582:216597
Nat Commun, 2023, 14(1):3251
Neuron, 2023, S0896-6273(23)00623-2
S8008 RGD (Arg-Gly-Asp) Peptides RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
J Sport Health Sci, 2024, S2095-2546(24)00124-8
iScience, 2024, 27(3):109119
Cell Stem Cell, 2023, 30(6):867-884.e11
S7844 Cyclo(RGDyK) TFA Cyclo(RGDyK) TFA is a salt formed by the combination of Cyclo(RGDyK) and trifluoroacetate (TFA). It is an effective and selective Integrin αvβ3 inhibitor with a low IC50 value (e.g., 20 nM). Cyclo(RGDyK) TFA is of great significance in the treatment of cardiovascular diseases, osteoporosis, inflammation and tumors.
J Clin Invest, 2024, e175147
JBMR Plus, 2024, 8(7):ziae066
Cell Commun Signal, 2023, 10.1186/s12964-022-01027-7
S7834 Cyclo(-RGDfK) TFA Cyclo(-RGDfK) TFA is the salt product of Cyclo(-RGDfK) and trifluoroacetic acid (TFA). The addition of TFA enhances stability and biocompatibility. Cyclo(-RGDfK) TFA effectively targets tumor microvessels and cancer cells by specifically binding to the cell surface Integrin αvβ3.
Pharmaceuticals (Basel), 2025, 18(4)549
Sci Adv, 2024, 10(43):eadp4726
bioRxiv, 2024, 2024.09.17.613509
S2885 A-205804 A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
Cell Biol Toxicol, 2024, 40(1):90
Stem Cell Res Ther, 2022, 13(1):218
Am J Rhinol Allergy, 2022, 19458924221086061
S6840 OSU-T315 OSU-T315 (ILK-IN-2) is a potent Integrin-Linked Kinase (ILK) inhibitor with IC50 of 0.6 μM. OSU-T315 induces autophagy and apoptosis, both of which are integral to its antiproliferative activity. OSU-T315 exhibits anti-tumor activity.
Exp Eye Res, 2023, 234:109609
S4513 RGD peptide (GRGDNP) RGD peptide (GRGDNP) is an inhibitor of binding of integrins to the extracellular matrixs. RGD peptide (GRGDNP) induces apoptosis presumably through direct activation of caspase-3.
Tradit Med Res, 2023, 8(9):50
E0790 ILK-IN-3 ILK-IN-3 is an integrin linked kinase (ILK) inhibitor with antitumor activity.
E7334New Cyclo(RGDyK) Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis.
E7759New GRGDSP GRGDSP is a fibronectin-derived peptide and an inhibitor of Integrin. It can be used for surface modification of cardiovascular implants, such as vascular grafts, to promote endothelialization, and also holds potential for hepatocellular carcinoma (HCC) treatment by inhibiting tumor cell adhesion and limiting metastasis.
E1385 Bexotegrast Bexotegrast(PLN-74809) is potent dual selective inhibitor of αvβ6 and αvβ1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-β activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).
S3408 A286982 A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively.
A2420 Anti-Integrin b1 / ITGB1 / CD29 Anti-Integrin b1 / ITGB1 / CD29 is a humanized monoclonal antibody directed against the human integrin receptor beta-1 subunit (CD29), with potential antineoplastic activity. MW: 145.5 kD.
A2873 Anti-ICAM3 / CD50 Anti-ICAM3 / CD50 is an IgG1 monoclonal antibody against intercellular adhesion molecules-3 (ICAM-3, also known as CD50)) with the potential to have anti-proliferative activities. MW: 145.22 KD.
A2464 Bersanlimab (Anti-ICAM1 / CD54) Bersanlimab (Anti-ICAM1 / CD54) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects. MW: 145.5 KD.
A2704 Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100) Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100) is a humanized monoclonal antibody directed against the alpha v beta 6 (αvβ6) integrin. It has a potential to be used in research on Idiopathic Pulmonary Fibrosis (IPF). MW : 144.88 kD.
A2712 Erlizumab (Anti-Integrin b2 / ITGB2 / CD18) Erlizumab (anti-Integrin b2 / ITGB2 / CD18) is a humanized monoclonal antibody targeted against Integrin beta-2 and used as a therapy for hemorrhagic shock. MW: 146.66 kD.
A2988 Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) is a monoclonal antibody targeting the α2 subunit (CD49b) of very late antigen-2 (VLA-2). It can be used for the research of multiple sclerosis. MW: 144.56 KD.
A2990 Intetumumab (Anti-Integrin aV / ITGAV / CD51) Intetumumab (Anti-Integrin aV / ITGAV / CD51) is a potent monoclonal antibody targeting αV-integrins. It can be used in research of uterine serous papillary carcinoma (USPC) treatment. MW :145.58 KD.
A2991 Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD.
A2744 Abituzumab (Anti-Integrin aV / ITGAV / CD51) Abituzumab (Anti-Integrin aV / ITGAV / CD51) is a humanized monoclonal antibody directed against the human alpha v integrin subunit with potential antiangiogenic and antineoplastic activities.MW: 144.78 kD.
A2745 Anti-Integrin a11 / ITAG11 Anti-Integrin a11 / ITAG11 is a monoclonal antibody against Integrin alpha 11 (ITGA11), a transmembrane glycoprotein expressed in adult cardiac and uterine smooth muscle and developing myocytes. MW: 145.7 KD.
A2761 Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) is a fully human monoclonal immunoglobulin G2 antibody that targets the alpha4beta7 integrin and prevents interaction with MADCAM-1. It has the potential to be used in research on inflammatory bowel disease (IBD). MW: 143.8 kD.
A2045 Vedolizumab (anti-α4β7-integrin) Vedolizumab (anti-α4β7-integrin) is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
S8454 ATN-161 ATN-161 is a novel small peptide antagonist of integrin α5β1. It binds to several integrins, including α5β1 and αvβ3, that play a role in angiogenesis and tumor progression.
Oncol Res, 2025, 33(2):443-464
Nat Commun, 2024, 15(1):5986
Int Immunopharmacol, 2024, 141:112947
S3714 Lifitegrast Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED.
Med Oncol, 2024, 41(8):188
World J Gastroenterol, 2023, 29(20):3103-3118
World J Gastroenterol, 2023, 29(20):3103-3118
S3085 Tirofiban Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
Food Funct, 2020, 11(1):139-152
S8594 Tirofiban Hydrochloride Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban.
J Immunother Cancer, 2024, 12(11)e009805
Transl Oncol, 2024, 39:101813
Front Cell Infect Microbiol, 2021, 11:783085
E1558New GSK-3008348 HCl GSK-3008348 HCl is a small molecule antagonist of integrin αvβ6 with an affinity (pIC50) value of 8.1 for αvβ6 in cell Adhesion assays.
S0314 TR-14035 TR-14035 (SB 683698, MDK-1191) is a a dual alpha4beta (α4β) integrin antagonist with IC50 of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively.
E4615New GLPG0187 GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity.
Sci Rep, 2025, 15(1):9147
S8306 Leukadherin-1 Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)).
International Immunopharmacology, 2023, Volume 118
Int Immunopharmacol, 2023, 118:110024
Front Immunol, 2022, 13:919444
E0462 Pyrintegrin Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival, also enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling.
Signal Transduct Target Ther, 2024, 9(1):109
Signal Transduct Target Ther, 2024, 9(1):109
F0362New Slug Rabbit mAb
F0632New Integrin β5 Rabbit mAb Integrin beta 5,Integrin β5
F0949New Integrin α5 Rabbit mAb Integrin alpha 5,Integrin alpha5,Integrin alphaV,Integrin α5
F0437New Integrin 3 Rabbit mAb CD61,CD61 (Integrin beta 3),Integrin beta 3,Integrin beta3,Integrin β3,Integrin β3/ITGB3/CD61
F1694New Integrin α2 Rabbit mAb Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12
F1452New Integrin β4 Rabbit mAb Integrin beta 4,Integrin beta4,Integrin β4
F0577New ILK1 Rabbit mAb ILK,ILK1,Integrin linked ILK
F1314New Talin-1 Rabbit mAb Neutrophil,Talin,Talin 1,Talin-1
F1640New Dysferlin Rabbit mAb
F2411New Keratin 12/K12 Rabbit mAb
E1558New GSK-3008348 HCl GSK-3008348 HCl is a small molecule antagonist of integrin αvβ6 with an affinity (pIC50) value of 8.1 for αvβ6 in cell Adhesion assays.
E4615New GLPG0187 GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity.
Sci Rep, 2025, 15(1):9147
E7334New Cyclo(RGDyK) Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis.
E7759New GRGDSP GRGDSP is a fibronectin-derived peptide and an inhibitor of Integrin. It can be used for surface modification of cardiovascular implants, such as vascular grafts, to promote endothelialization, and also holds potential for hepatocellular carcinoma (HCC) treatment by inhibiting tumor cell adhesion and limiting metastasis.

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Tags: Integrin inhibitor|Integrin agonist|Integrin activator|Integrin inducer|Integrin antagonist|Integrin signaling pathway|Integrin assay kit