S7077 |
Cilengitide trifluoroacetate
|
Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. |
-
Int J Mol Sci, 2025, 26(6)2465
-
Microbiol Spectr, 2025, 13(2):e0222124
-
iScience, 2024, 27(10):110862
|
|
S6387 |
Cilengitide
|
Cilengitide (EMD 121974, EMD-12192, EMD-85189, NSC-707544) is a potent and selective inhibitor of the integrins ανβ3 and ανβ5 with IC50 of 4 and 79 nM, respectively. |
-
Nat Commun, 2025, 16(1):2254
-
NPJ Regen Med, 2024, 9(1):4
-
World J Gastroenterol, 2024, 30(7):728-741
|
|
S7540 |
SB273005
|
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
|
-
Cancer Lett, 2024, 582:216597
-
Nat Commun, 2023, 14(1):3251
-
Neuron, 2023, S0896-6273(23)00623-2
|
|
S8008 |
RGD (Arg-Gly-Asp) Peptides
|
RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. |
-
J Sport Health Sci, 2024, S2095-2546(24)00124-8
-
iScience, 2024, 27(3):109119
-
Cell Stem Cell, 2023, 30(6):867-884.e11
|
|
S8454 |
ATN-161
|
ATN-161 is a novel small peptide antagonist of integrin α5β1. It binds to several integrins, including α5β1 and αvβ3, that play a role in angiogenesis and tumor progression.
|
-
Oncol Res, 2025, 33(2):443-464
-
Nat Commun, 2024, 15(1):5986
-
Int Immunopharmacol, 2024, 141:112947
|
|
S7844 |
Cyclo(RGDyK) TFA
|
Cyclo(RGDyK) TFA is a salt formed by the combination of Cyclo(RGDyK) and trifluoroacetate (TFA). It is an effective and selective Integrin αvβ3 inhibitor with a low IC50 value (e.g., 20 nM). Cyclo(RGDyK) TFA is of great significance in the treatment of cardiovascular diseases, osteoporosis, inflammation and tumors.
|
-
J Clin Invest, 2024, e175147
-
JBMR Plus, 2024, 8(7):ziae066
-
Cell Commun Signal, 2023, 10.1186/s12964-022-01027-7
|
|
S7834 |
Cyclo(-RGDfK) TFA
|
Cyclo(-RGDfK) TFA is the salt product of Cyclo(-RGDfK) and trifluoroacetic acid (TFA). The addition of TFA enhances stability and biocompatibility. Cyclo(-RGDfK) TFA effectively targets tumor microvessels and cancer cells by specifically binding to the cell surface Integrin αvβ3.
|
-
Pharmaceuticals (Basel), 2025, 18(4)549
-
Sci Adv, 2024, 10(43):eadp4726
-
bioRxiv, 2024, 2024.09.17.613509
|
|
S8306 |
Leukadherin-1
|
Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)). |
-
International Immunopharmacology, 2023, Volume 118
-
Int Immunopharmacol, 2023, 118:110024
-
Front Immunol, 2022, 13:919444
|
|
S2885 |
A-205804
|
A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. |
-
Cell Biol Toxicol, 2024, 40(1):90
-
Stem Cell Res Ther, 2022, 13(1):218
-
Am J Rhinol Allergy, 2022, 19458924221086061
|
|
S3714 |
Lifitegrast
|
Lifitegrast (SAR1118,SHP-606) is a novel small molecule integrin antagonist that inhibits a specific T cell-mediated inflammatory pathway involved in the pathogenesis of DED. |
-
Med Oncol, 2024, 41(8):188
-
World J Gastroenterol, 2023, 29(20):3103-3118
-
World J Gastroenterol, 2023, 29(20):3103-3118
|
|
S3085 |
Tirofiban
|
Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM. |
-
Food Funct, 2020, 11(1):139-152
|
|
S8594 |
Tirofiban Hydrochloride
|
Tirofiban Hydrochloride (MK-383) is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation. It is more soluable than Tirofiban. |
-
J Immunother Cancer, 2024, 12(11)e009805
-
Transl Oncol, 2024, 39:101813
-
Front Cell Infect Microbiol, 2021, 11:783085
|
|
S6840 |
OSU-T315
|
OSU-T315 (ILK-IN-2) is a potent Integrin-Linked Kinase (ILK) inhibitor with IC50 of 0.6 μM. OSU-T315 induces autophagy and apoptosis, both of which are integral to its antiproliferative activity. OSU-T315 exhibits anti-tumor activity. |
-
Exp Eye Res, 2023, 234:109609
|
|
F0362New |
Slug Rabbit mAb
|
|
|
|
F0996 |
Integrin αV Rabbit mAb
|
Integrin alpha V,Integrin αV,Integrin αV/ITGAV |
|
|
F0632New |
Integrin β5 Rabbit mAb
|
Integrin beta 5,Integrin β5 |
|
|
F0949New |
Integrin α5 Rabbit mAb
|
Integrin alpha 5,Integrin alpha5,Integrin alphaV,Integrin α5 |
|
|
F0437New |
Integrin 3 Rabbit mAb
|
CD61,CD61 (Integrin beta 3),Integrin beta 3,Integrin beta3,Integrin β3,Integrin β3/ITGB3/CD61 |
|
|
F1694New |
Integrin α2 Rabbit mAb
|
Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12 |
|
|
F1452New |
Integrin β4 Rabbit mAb
|
Integrin beta 4,Integrin beta4,Integrin β4 |
|
|
F0577New |
ILK1 Rabbit mAb
|
ILK,ILK1,Integrin linked ILK |
|
|
F1314New |
Talin-1 Rabbit mAb
|
Neutrophil,Talin,Talin 1,Talin-1 |
|
|
F1640New |
Dysferlin Rabbit mAb
|
|
|
|
F2411New |
Keratin 12/K12 Rabbit mAb
|
|
|
|
E0462 |
Pyrintegrin
|
Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival, also enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling. |
-
Signal Transduct Target Ther, 2024, 9(1):109
-
Signal Transduct Target Ther, 2024, 9(1):109
|
|
A2420 |
Anti-Integrin b1 / ITGB1 / CD29
|
Anti-Integrin b1 / ITGB1 / CD29 is a humanized monoclonal antibody directed against the human integrin receptor beta-1 subunit (CD29), with potential antineoplastic activity. MW: 145.5 kD. |
|
|
A2873 |
Anti-ICAM3 / CD50
|
Anti-ICAM3 / CD50 is an IgG1 monoclonal antibody against intercellular adhesion molecules-3 (ICAM-3, also known as CD50)) with the potential to have anti-proliferative activities. MW: 145.22 KD. |
|
|
E1558New |
GSK-3008348 HCl
|
GSK-3008348 HCl is a small molecule antagonist of integrin αvβ6 with an affinity (pIC50) value of 8.1 for αvβ6 in cell Adhesion assays. |
|
|
S0314 |
TR-14035
|
TR-14035 (SB 683698, MDK-1191) is a a dual alpha4beta (α4β) integrin antagonist with IC50 of 7 nM and 87 nM for alpha4beta7 (α4β7) and alpha4beta1 (α4β1), respectively. |
|
|
E4615New |
GLPG0187
|
GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity. |
-
Sci Rep, 2025, 15(1):9147
|
|
A2464 |
Bersanlimab (Anti-ICAM1 / CD54)
|
Bersanlimab (Anti-ICAM1 / CD54) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects. MW: 145.5 KD. |
|
|
S4513 |
RGD peptide (GRGDNP)
|
RGD peptide (GRGDNP) is an inhibitor of binding of integrins to the extracellular matrixs. RGD peptide (GRGDNP) induces apoptosis presumably through direct activation of caspase-3. |
-
Tradit Med Res, 2023, 8(9):50
|
|
E0790 |
ILK-IN-3
|
ILK-IN-3 is an integrin linked kinase (ILK) inhibitor with antitumor activity. |
|
|
E7334New |
Cyclo(RGDyK)
|
Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis. |
|
|
A2704 |
Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100)
|
Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100) is a humanized monoclonal antibody directed against the alpha v beta 6 (αvβ6) integrin. It has a potential to be used in research on Idiopathic Pulmonary Fibrosis (IPF). MW : 144.88 kD. |
|
|
A2712 |
Erlizumab (Anti-Integrin b2 / ITGB2 / CD18)
|
Erlizumab (anti-Integrin b2 / ITGB2 / CD18) is a humanized monoclonal antibody targeted against Integrin beta-2 and used as a therapy for hemorrhagic shock. MW: 146.66 kD. |
|
|
A2988 |
Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1))
|
Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) is a monoclonal antibody targeting the α2 subunit (CD49b) of very late antigen-2 (VLA-2). It can be used for the research of multiple sclerosis. MW: 144.56 KD. |
|
|
A2990 |
Intetumumab (Anti-Integrin aV / ITGAV / CD51)
|
Intetumumab (Anti-Integrin aV / ITGAV / CD51) is a potent monoclonal antibody targeting αV-integrins. It can be used in research of uterine serous papillary carcinoma (USPC) treatment. MW :145.58 KD. |
|
|
A2991 |
Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3))
|
Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD. |
|
|
A2744 |
Abituzumab (Anti-Integrin aV / ITGAV / CD51)
|
Abituzumab (Anti-Integrin aV / ITGAV / CD51) is a humanized monoclonal antibody directed against the human alpha v integrin subunit with potential antiangiogenic and antineoplastic activities.MW: 144.78 kD. |
|
|
A2745 |
Anti-Integrin a11 / ITAG11
|
Anti-Integrin a11 / ITAG11 is a monoclonal antibody against Integrin alpha 11 (ITGA11), a transmembrane glycoprotein expressed in adult cardiac and uterine smooth muscle and developing myocytes. MW: 145.7 KD. |
|
|
E7759New |
GRGDSP
|
GRGDSP is a fibronectin-derived peptide and an inhibitor of Integrin. It can be used for surface modification of cardiovascular implants, such as vascular grafts, to promote endothelialization, and also holds potential for hepatocellular carcinoma (HCC) treatment by inhibiting tumor cell adhesion and limiting metastasis. |
|
|
A2761 |
Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7)
|
Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) is a fully human monoclonal immunoglobulin G2 antibody that targets the alpha4beta7 integrin and prevents interaction with MADCAM-1. It has the potential to be used in research on inflammatory bowel disease (IBD). MW: 143.8 kD. |
|
|
E1385 |
Bexotegrast
|
Bexotegrast(PLN-74809) is potent dual selective inhibitor of αvβ6 and αvβ1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-β activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP). |
|
|
S3408 |
A286982
|
A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively. |
|
|
A2045 |
Vedolizumab (anti-α4β7-integrin)
|
Vedolizumab (anti-α4β7-integrin) is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease. |
|
|
S7077 |
Cilengitide trifluoroacetate
|
Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2. |
- Int J Mol Sci, 2025, 26(6)2465
- Microbiol Spectr, 2025, 13(2):e0222124
- iScience, 2024, 27(10):110862
|
|
S6387 |
Cilengitide
|
Cilengitide (EMD 121974, EMD-12192, EMD-85189, NSC-707544) is a potent and selective inhibitor of the integrins ανβ3 and ανβ5 with IC50 of 4 and 79 nM, respectively. |
- Nat Commun, 2025, 16(1):2254
- NPJ Regen Med, 2024, 9(1):4
- World J Gastroenterol, 2024, 30(7):728-741
|
|
S7540 |
SB273005
|
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
|
- Cancer Lett, 2024, 582:216597
- Nat Commun, 2023, 14(1):3251
- Neuron, 2023, S0896-6273(23)00623-2
|
|
S8008 |
RGD (Arg-Gly-Asp) Peptides
|
RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. |
- J Sport Health Sci, 2024, S2095-2546(24)00124-8
- iScience, 2024, 27(3):109119
- Cell Stem Cell, 2023, 30(6):867-884.e11
|
|
S7844 |
Cyclo(RGDyK) TFA
|
Cyclo(RGDyK) TFA is a salt formed by the combination of Cyclo(RGDyK) and trifluoroacetate (TFA). It is an effective and selective Integrin αvβ3 inhibitor with a low IC50 value (e.g., 20 nM). Cyclo(RGDyK) TFA is of great significance in the treatment of cardiovascular diseases, osteoporosis, inflammation and tumors.
|
- J Clin Invest, 2024, e175147
- JBMR Plus, 2024, 8(7):ziae066
- Cell Commun Signal, 2023, 10.1186/s12964-022-01027-7
|
|
S7834 |
Cyclo(-RGDfK) TFA
|
Cyclo(-RGDfK) TFA is the salt product of Cyclo(-RGDfK) and trifluoroacetic acid (TFA). The addition of TFA enhances stability and biocompatibility. Cyclo(-RGDfK) TFA effectively targets tumor microvessels and cancer cells by specifically binding to the cell surface Integrin αvβ3.
|
- Pharmaceuticals (Basel), 2025, 18(4)549
- Sci Adv, 2024, 10(43):eadp4726
- bioRxiv, 2024, 2024.09.17.613509
|
|
S2885 |
A-205804
|
A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively. |
- Cell Biol Toxicol, 2024, 40(1):90
- Stem Cell Res Ther, 2022, 13(1):218
- Am J Rhinol Allergy, 2022, 19458924221086061
|
|
S6840 |
OSU-T315
|
OSU-T315 (ILK-IN-2) is a potent Integrin-Linked Kinase (ILK) inhibitor with IC50 of 0.6 μM. OSU-T315 induces autophagy and apoptosis, both of which are integral to its antiproliferative activity. OSU-T315 exhibits anti-tumor activity. |
- Exp Eye Res, 2023, 234:109609
|
|
S4513 |
RGD peptide (GRGDNP)
|
RGD peptide (GRGDNP) is an inhibitor of binding of integrins to the extracellular matrixs. RGD peptide (GRGDNP) induces apoptosis presumably through direct activation of caspase-3. |
- Tradit Med Res, 2023, 8(9):50
|
|
E0790 |
ILK-IN-3
|
ILK-IN-3 is an integrin linked kinase (ILK) inhibitor with antitumor activity. |
|
|
E7334New |
Cyclo(RGDyK)
|
Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis. |
|
|
E7759New |
GRGDSP
|
GRGDSP is a fibronectin-derived peptide and an inhibitor of Integrin. It can be used for surface modification of cardiovascular implants, such as vascular grafts, to promote endothelialization, and also holds potential for hepatocellular carcinoma (HCC) treatment by inhibiting tumor cell adhesion and limiting metastasis. |
|
|
E1385 |
Bexotegrast
|
Bexotegrast(PLN-74809) is potent dual selective inhibitor of αvβ6 and αvβ1 integrins with Kd of 5.7 nM and 3.4 nM, respectively. It has antifibrogenic effects, blocks multiple TGF-β activation pathways in the fibrotic lung, and is useful for researching fibrosis, including idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP). |
|
|
S3408 |
A286982
|
A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively. |
|
|
A2420 |
Anti-Integrin b1 / ITGB1 / CD29
|
Anti-Integrin b1 / ITGB1 / CD29 is a humanized monoclonal antibody directed against the human integrin receptor beta-1 subunit (CD29), with potential antineoplastic activity. MW: 145.5 kD. |
|
|
A2873 |
Anti-ICAM3 / CD50
|
Anti-ICAM3 / CD50 is an IgG1 monoclonal antibody against intercellular adhesion molecules-3 (ICAM-3, also known as CD50)) with the potential to have anti-proliferative activities. MW: 145.22 KD. |
|
|
A2464 |
Bersanlimab (Anti-ICAM1 / CD54)
|
Bersanlimab (Anti-ICAM1 / CD54) is a fully human monoclonal antibody that targets intercellular adhesion molecule-1 (ICAM-1 or CD54). Bersanlimab has anticancer effects. MW: 145.5 KD. |
|
|
A2704 |
Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100)
|
Anti-Integrin aVb6 (ITGAV & ITGB6) (STX-100) is a humanized monoclonal antibody directed against the alpha v beta 6 (αvβ6) integrin. It has a potential to be used in research on Idiopathic Pulmonary Fibrosis (IPF). MW : 144.88 kD. |
|
|
A2712 |
Erlizumab (Anti-Integrin b2 / ITGB2 / CD18)
|
Erlizumab (anti-Integrin b2 / ITGB2 / CD18) is a humanized monoclonal antibody targeted against Integrin beta-2 and used as a therapy for hemorrhagic shock. MW: 146.66 kD. |
|
|
A2988 |
Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1))
|
Vatelizumab (Anti-Integrin a2b1 (ITGA2 & ITGB1)) is a monoclonal antibody targeting the α2 subunit (CD49b) of very late antigen-2 (VLA-2). It can be used for the research of multiple sclerosis. MW: 144.56 KD. |
|
|
A2990 |
Intetumumab (Anti-Integrin aV / ITGAV / CD51)
|
Intetumumab (Anti-Integrin aV / ITGAV / CD51) is a potent monoclonal antibody targeting αV-integrins. It can be used in research of uterine serous papillary carcinoma (USPC) treatment. MW :145.58 KD. |
|
|
A2991 |
Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3))
|
Etaracizumab (Anti-Integrin aVb3 (ITGAV & ITGB3)) is an IgG1 monoclonal antibody targeting αvβ3 integrin. It inhibits angiogenesis and melanoma tumor growth and can be used to research anticancer. MW :144.18 KD. |
|
|
A2744 |
Abituzumab (Anti-Integrin aV / ITGAV / CD51)
|
Abituzumab (Anti-Integrin aV / ITGAV / CD51) is a humanized monoclonal antibody directed against the human alpha v integrin subunit with potential antiangiogenic and antineoplastic activities.MW: 144.78 kD. |
|
|
A2745 |
Anti-Integrin a11 / ITAG11
|
Anti-Integrin a11 / ITAG11 is a monoclonal antibody against Integrin alpha 11 (ITGA11), a transmembrane glycoprotein expressed in adult cardiac and uterine smooth muscle and developing myocytes. MW: 145.7 KD. |
|
|
A2761 |
Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7)
|
Abrilumab (Anti-Integrin a4b7 ITGA4 & ITGB7) is a fully human monoclonal immunoglobulin G2 antibody that targets the alpha4beta7 integrin and prevents interaction with MADCAM-1. It has the potential to be used in research on inflammatory bowel disease (IBD). MW: 143.8 kD. |
|
|
A2045 |
Vedolizumab (anti-α4β7-integrin)
|
Vedolizumab (anti-α4β7-integrin) is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease. |
|
|
F0362New |
Slug Rabbit mAb
|
|
|
|
F0632New |
Integrin β5 Rabbit mAb
|
Integrin beta 5,Integrin β5 |
|
|
F0949New |
Integrin α5 Rabbit mAb
|
Integrin alpha 5,Integrin alpha5,Integrin alphaV,Integrin α5 |
|
|
F0437New |
Integrin 3 Rabbit mAb
|
CD61,CD61 (Integrin beta 3),Integrin beta 3,Integrin beta3,Integrin β3,Integrin β3/ITGB3/CD61 |
|
|
F1694New |
Integrin α2 Rabbit mAb
|
Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12 |
|
|
F1452New |
Integrin β4 Rabbit mAb
|
Integrin beta 4,Integrin beta4,Integrin β4 |
|
|
F0577New |
ILK1 Rabbit mAb
|
ILK,ILK1,Integrin linked ILK |
|
|
F1314New |
Talin-1 Rabbit mAb
|
Neutrophil,Talin,Talin 1,Talin-1 |
|
|
F1640New |
Dysferlin Rabbit mAb
|
|
|
|
F2411New |
Keratin 12/K12 Rabbit mAb
|
|
|
|
E1558New |
GSK-3008348 HCl
|
GSK-3008348 HCl is a small molecule antagonist of integrin αvβ6 with an affinity (pIC50) value of 8.1 for αvβ6 in cell Adhesion assays. |
|
|
E4615New |
GLPG0187
|
GLPG0187 is a broad-spectrum antagonist of integrin receptor. It inhibits αvβ1-integrin with an IC50 value of 1.3 nM. GLPG0187 also inhibits migrasome biogenesis without cytotoxicity. GLPG0187 exhibits potent antitumor activity. |
- Sci Rep, 2025, 15(1):9147
|
|
E7334New |
Cyclo(RGDyK)
|
Cyclo(RGDyK) is a potent and selective inhibitor of αVβ3 integrin . It significantly reduces lung inflammation and fibrosis induced by influenza A virus, and improves lung morphology, lowers pulmonary fibrosis scores, and suppresses the expression of αVβ3, TGF-β1, NF-κB p65, p38 MAPK, and HIF-1α, confirming its protective effects against ALI and pulmonary fibrosis. |
|
|
E7759New |
GRGDSP
|
GRGDSP is a fibronectin-derived peptide and an inhibitor of Integrin. It can be used for surface modification of cardiovascular implants, such as vascular grafts, to promote endothelialization, and also holds potential for hepatocellular carcinoma (HCC) treatment by inhibiting tumor cell adhesion and limiting metastasis. |
|
|