Home Cytoskeletal Signaling Gap-Junction

Gap-Junction

Cytoskeletal Signaling

CDK Chk ROCK PLK Antimetabolites APC Wee1 MPS1 Rho Myc DYRK BMI-1 eIF LIM kinase PFKFB RUNX Nur77 FOXM1 Choline kinase Haspin Kinase Mad2 p21 Cyclin CDK4/6
  • All (4)
  • Gap-Junction Inhibitors (3)
  • Gap-Junction Modulator (1)
  • New Gap-Junction Products
Cat.No. Product Name Information Product Use Citations Product Validations
S0339 Gap 26 Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. This compound blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP release.
E7978 Danegaptide Danegaptide is a potent and orally active gap-junction modifier that improves cardiac conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model by enhancing gap-junction communication.
S6946 Gap19 Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. This compound blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.
E0040 Gap 27

Gap 27 is a synthetic connexin-mimetic peptide and acts as a gap junction inhibitor. This compound is highly effective in interrupting co-operative cell-cell interactions, such as the synchronous beating of embryonic cardiomyocytes.
S0339 Gap 26 Gap 26, a connexin mimetic peptide that composeds of residue no. 63-75 of the extracellular loop 1 of connexin 43 (Cx43), is a gap junction inhibitor. This compound blocks photoliberating inositol-1,4,5-trisphosphate triggers ATP release.
S6946 Gap19 Gap19 is a nonapeptide derived from the cytoplasmic loop (CL) of Cx43 and acts as a selective connexin 43 (Cx43) hemichannel blocker. This compound blocks Cx43 hemichannels without inhibiting gap junctions (GJs) at IC50 of 6.5 μM when applied intracellulary.
E0040 Gap 27

Gap 27 is a synthetic connexin-mimetic peptide and acts as a gap junction inhibitor. This compound is highly effective in interrupting co-operative cell-cell interactions, such as the synchronous beating of embryonic cardiomyocytes.
E7978 Danegaptide Danegaptide is a potent and orally active gap-junction modifier that improves cardiac conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model by enhancing gap-junction communication.