Actin

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Actin Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S7497 CK-636 CK-636 (CK-0944636) is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
J Biol Chem, 2024, 300(12):107942
Elife, 2021, 10e65910
Theranostics, 2019, 9(25):7628-7647
S8184 Cytochalasin D Cytochalasin D (Zygosporin A, NSC 209835) is a potent actin polymerization inhibitor derived from fungus. Cytochalasin D inhibits actin filament dynamics in cells. It induces phosphorylation and cytoplasmic retention of Yap.
Nat Commun, 2025, 16(1):4069
Cell Regen, 2025, 14(1):21
Cell Prolif, 2024, e13728.
S5256 Benproperine phosphate Benproperine phosphate (Blascorid, Pirexyl), a cough suppressant, is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate suppresses cancer cell migration and tumor metastasis.
Mol Oncol, 2020, 10.1002/1878-0261.12854
F0012 β-Actin Antibody [C21N23] ACTB,beta Actin,beta Actin Loading Control,beta-Actin,β-Actin
J Plast Surg Hand Surg, 2021, 55(5):284-293
F0017New α-Smooth Muscle Actin Antibody [L19D14] Actin, alpha-Smooth Muscle,Actin, α-Smooth Muscle,alpha smooth muscle Actin,Alpha-Smooth Muscle Actin,Smooth Muscle Actin,α-Actin,α-Smooth Muscle Actin, α-SMA, a-SMA
Bioact Mater, 2024, 34:51-63
J Plast Surg Hand Surg, 2021, 55(5):284-293
F0082 Actin Antibody [A24J5] Actin,Actin Ab-5,pan Actin,Pan-Actin
F0440 Neurofilament-L Antibody [L10B15]
F0695 Neurofilament-M Antibody [H7L9] 160 kD Neurofilament Medium,NEFM,Neurofilament 145 kDa,Neurofilament 160,Neurofilament 160 kDa,Neurofilament M,Neurofilament-M
F1648 PABP1 Antibody [H6J19] PABP, PABP1
F0278 Cofilin Antibody [D9A5] Cofilin,Cofilin 1
F2199New α Actinin 1/ACTN1 Antibody [C8H2] Actinin alpha,alpha Actinin/ACTN1,alpha-Actinin,α-Actinin
F2226 α smooth muscle Actin (acetyl Glu 3) + Actin γ2 (acetyl Glu3) Antibody [H16P9]
F0640 N-WASP Antibody [K15N2]
F0417 VASP Antibody [A20G16]
F1962 Phospho-Lamin A/C (Ser22) Antibody [D12F9]
F1379 Tropomyosin-1 Antibody [G4H1] Tropomyosin (Sarcomeric),Tropomyosin-1
F2176 SUN2 Antibody [D3P18]
F2446New γ Actin Antibody [A4H18] gamma Actin,gamma-Actin
F2365New Arp3 C-terminal Antibody [F20N23]
F2091 Fascin Antibody [N3C10]
F2612New ARPC2 Antibody [B10F4] ARPC2,p34-Arc/ARPC2
F2033 α Actinin 4 Antibody [D15C11] alpha Actinin 4,α-Actinin 4
F2681New Cytokeratin 5 Antibody [G20N20] Cytokeratin 5 + 6,Cytokeratin 5/6
F2188 Cytokeratin 13 Antibody [L12L19]
F2756New CCT2 Antibody [C14D6]
F1440 Gelsolin Antibody [D8P23]
F1636New Phospho-RAB10 (Thr73) Antibody [M19N14]
F1478New Phospho-Zyxin (Ser142/143) Antibody [L24L6]
E1042 SMIFH2

SMIFH2 is a specific inhibitor of formin that inhibits formin-driven actin polymerization in vitro with IC50s ranging from 5 to 15 μM for different formins.
S6673 CCG-222740 CCG-222740 is a Rho/MRTF pathway inhibitor. CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression.
E0076 Simufilam dihydrochloride Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7 nAChR/TLR4 associations and downstream pathologies.
E2956 Cytochalasin C Cytochalasin C is a cell-permeable fungal metabolite that has been found in C. globosum. Cytochalasin C is an inhibitor of actin polymerization. It induces the formation of nuclear rodlets.
S3206 5a-Pregnane-3,20-dione 5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) is the endogenous progesterone metabolite. 5a-Pregnane-3,20-dione depolymerizes actin and decreases expression of actin and vinculin. 5a-Pregnane-3,20-dione is involved in promoting breast neoplasia and metastasis by affecting adhesion and cytoskeletal molecules.
S7690 CK-666 CK-666 is an inhibitor of the actin-related protein 2/3 (Arp2/3) complex with IC50 of 17 μM and 5 μM for BtArp2/3 complex and SpArp2/3 complex, respectively.
Res Sq, 2023, rs.3.rs-3372987
F2616New Cytokeratin 4 Antibody [G16J4]
S7497 CK-636 CK-636 (CK-0944636) is an Arp2/3 complex inhibitor with IC50 of 4 μM, 24 μM and 32 μM for inhibition of actin polymerization induced by human, fission yeast and bovine Arp2/3 complex, respectively.
J Biol Chem, 2024, 300(12):107942
Elife, 2021, 10e65910
Theranostics, 2019, 9(25):7628-7647
S8184 Cytochalasin D Cytochalasin D (Zygosporin A, NSC 209835) is a potent actin polymerization inhibitor derived from fungus. Cytochalasin D inhibits actin filament dynamics in cells. It induces phosphorylation and cytoplasmic retention of Yap.
Nat Commun, 2025, 16(1):4069
Cell Regen, 2025, 14(1):21
Cell Prolif, 2024, e13728.
S5256 Benproperine phosphate Benproperine phosphate (Blascorid, Pirexyl), a cough suppressant, is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate suppresses cancer cell migration and tumor metastasis.
Mol Oncol, 2020, 10.1002/1878-0261.12854
E1042 SMIFH2

SMIFH2 is a specific inhibitor of formin that inhibits formin-driven actin polymerization in vitro with IC50s ranging from 5 to 15 μM for different formins.
S6673 CCG-222740 CCG-222740 is a Rho/MRTF pathway inhibitor. CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression.
E2956 Cytochalasin C Cytochalasin C is a cell-permeable fungal metabolite that has been found in C. globosum. Cytochalasin C is an inhibitor of actin polymerization. It induces the formation of nuclear rodlets.
S3206 5a-Pregnane-3,20-dione 5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) is the endogenous progesterone metabolite. 5a-Pregnane-3,20-dione depolymerizes actin and decreases expression of actin and vinculin. 5a-Pregnane-3,20-dione is involved in promoting breast neoplasia and metastasis by affecting adhesion and cytoskeletal molecules.
S7690 CK-666 CK-666 is an inhibitor of the actin-related protein 2/3 (Arp2/3) complex with IC50 of 17 μM and 5 μM for BtArp2/3 complex and SpArp2/3 complex, respectively.
Res Sq, 2023, rs.3.rs-3372987
E0076 Simufilam dihydrochloride Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7 nAChR/TLR4 associations and downstream pathologies.
F0017New α-Smooth Muscle Actin Antibody [L19D14] Actin, alpha-Smooth Muscle,Actin, α-Smooth Muscle,alpha smooth muscle Actin,Alpha-Smooth Muscle Actin,Smooth Muscle Actin,α-Actin,α-Smooth Muscle Actin, α-SMA, a-SMA
Bioact Mater, 2024, 34:51-63
J Plast Surg Hand Surg, 2021, 55(5):284-293
F2199New α Actinin 1/ACTN1 Antibody [C8H2] Actinin alpha,alpha Actinin/ACTN1,alpha-Actinin,α-Actinin
F2446New γ Actin Antibody [A4H18] gamma Actin,gamma-Actin
F2365New Arp3 C-terminal Antibody [F20N23]
F2612New ARPC2 Antibody [B10F4] ARPC2,p34-Arc/ARPC2
F2681New Cytokeratin 5 Antibody [G20N20] Cytokeratin 5 + 6,Cytokeratin 5/6
F2756New CCT2 Antibody [C14D6]
F1636New Phospho-RAB10 (Thr73) Antibody [M19N14]
F1478New Phospho-Zyxin (Ser142/143) Antibody [L24L6]
F2616New Cytokeratin 4 Antibody [G16J4]

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