| S3114 |
L-Ascorbic Acid (Vitamin C)
|
Vitamin C (L-Ascorbic acid) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.
|
-
bioRxiv, July 14, 2025, nan
-
Cellular and Molecular Life Sciences, February 16, 2024, 92
-
Biomaterials, 2025, 314:122873
|
|
| S1469 |
Calcifediol
|
Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol) is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).
|
-
The Journal of Immunology, July 15, 2020, 398-406
-
Front Pharmacol, 2023, 14:1135516
-
Frontiers in Pharmacology, 2023, 1135516
|
|
| S1468 |
Alfacalcidol
|
Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.
|
-
Developmental Cell, March 25, 2019, 853-863.e5
-
Antimicrobial Agents and Chemotherapy, December 21, 2017, e01675-17
-
International Journal of Molecular Sciences, August 19, 2022, 9366
|
|
| S3665 |
Trolox
|
Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.
|
-
Autophagy, March 22, 2025, 1791-1801
-
Biochemistry, April 3, 2024, 984-999
-
Nat Commun, 2025, 16(1):6617
|
|
| S6104 |
(±)-α-Tocopherol
|
(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.
|
-
Cell Death & Differentiation, July 21, 2023, 1988-2004
-
Cell Death and Differentiation, July 2023, 1988-2004
-
Cell Death Dis, 2025, 16(1):396
|
|
| S3739 |
MC903 (Calcipotriene)
|
Calcipotriene (MC903) is a synthetic derivative of calcitriol, a form of vitamin D. It can induce differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and lead to normalization of epidermal growth. Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.Solutions are unstable and should be fresh-prepared.
|
-
Int Immunopharmacol, 2025, 164:115403
-
Nutrients, 2024, 16(17)3021
-
Arch Dermatol Res, 2024, 316(8):585
|
|
| S1467 |
Doxercalciferol
|
Doxercalciferol (1α-hydroxyvitamin D2) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
|
-
International Immunopharmacology, 2024, 111357
-
FEBS Open Bio, 2023, 13(9):1789-1806
-
Int J Mol Sci, 2022, 23(16)9366
|
|
| S6681 |
Paricalcitol
|
Paricalcitol is a selective vitamin D receptor agonist. This compound suppresses parathyroid hormone mRNA expression and inhibits parathyroid cell proliferation. It is used to treat secondary hyperparathyroidism in chronic kidney disease.
|
-
Redox Biol, 2025, 80:103518
-
Redox Biol, 2024, 70:103062
-
Front Pharmacol, 2024, 15:1421577
|
|
| S1902 |
Vitamin B12
|
Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
|
-
J Mol Model, 2022, 28(6):153
-
Cell Chem Biol, 2021, S2451-9456(21)00213-0
-
Gastroenterology, 2019, 10.1053/j
|
|
| S1744 |
Nicotinic Acid
|
Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.
|
-
bioRxiv, July 13, 2023, 2023.07.12.548707
-
Gut Microbes, 2022, 2096989
-
Gut Microbes, 2022, 14(1):2096989
|
|