Vitamin

Inhibitory Selectivity
Solubility

Catalog No.	Product Name	Solubility(25°C)
Catalog No.	Product Name	Water	DMSO	Alcohol
S1469	Calcifediol	<1 mg/mL	80 mg/mL	20 mg/mL
S1468	Alfacalcidol	<1 mg/mL	80 mg/mL	80 mg/mL
S1921	Phenindione	<1 mg/mL	44 mg/mL	15 mg/mL
S4144	Amprolium HCl	63 mg/mL	2 mg/mL	<1 mg/mL
S1466	Calcitriol	<1 mg/mL	83 mg/mL	83 mg/mL
S3114	Vitamin C	35 mg/mL	35 mg/mL	<1 mg/mL
S1467	Doxercalciferol	<1 mg/mL	83 mg/mL	70 mg/mL
S5568	Tocofersolan	-1 mg/mL	100 mg/mL	-1 mg/mL
S5592	Vitamin A	-1 mg/mL	57 mg/mL	-1 mg/mL
S5386	7-Dehydrocholesterol	-1 mg/mL	76 mg/mL	-1 mg/mL
S5203	Sulbutiamine	-1 mg/mL	100 mg/mL	-1 mg/mL
S5558	D-Pantothenate Sodium	-1 mg/mL	6 mg/mL	-1 mg/mL
S5474	Dibenzoyl Thiamine	-1 mg/mL	98 mg/mL	-1 mg/mL
S5311	Pyridoxal phosphate	6 mg/mL	10 mg/mL	<1 mg/mL
S5082	Vitamin K2	-1 mg/mL	88 mg/mL	-1 mg/mL
S4987	Inositol niacinate	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S4994	Methylcobalamin	-1 mg/mL	100 mg/mL	-1 mg/mL
S5220	D-Pantethine	100 mg/mL	<1 mg/mL	-1 mg/mL
S4871	Pyridoxal 5-phosphate monohydrate	-1 mg/mL	22 mg/mL	-1 mg/mL
S3980	Pyridoxine	-1 mg/mL	33 mg/mL	-1 mg/mL
S4779	Menadiol Diacetate	-1 mg/mL	51 mg/mL	-1 mg/mL
S4811	VitaMin U	39 mg/mL	<1 mg/mL	-1 mg/mL
S3130	Biotin (Vitamin B7)	<1 mg/mL	49 mg/mL	<1 mg/mL
S1902	Vitamin B12	6 mg/mL	75 mg/mL	10 mg/mL
S1744	Nicotinic Acid	2 mg/mL	25 mg/mL	<1 mg/mL
S4063	cholecalciferol (Vitamin D3)	<1 mg/mL	77 mg/mL	77 mg/mL
S1767	Beta Carotene	<1 mg/mL	4 mg/mL	5 mg/mL
S2540	Riboflavin	<1 mg/mL	0.1 mg/mL	<1 mg/mL
S3211	Thiamine HCl (Vitamin B1)	68 mg/mL	<1 mg/mL	<1 mg/mL
S4503	Calcium D-Panthotenate	44 mg/mL	44 mg/mL	<1 mg/mL
S4126	Retinyl (Vitamin A) Palmitate	<1 mg/mL	3 mg/mL	5 mg/mL
S4605	Folic acid	<1 mg/mL	2 mg/mL	<1 mg/mL
S2297	Ergosterol	<1 mg/mL	0.01 mg/mL	<1 mg/mL
S4083	Vitamin A Acetate	<1 mg/mL	65 mg/mL	65 mg/mL
S3665	Trolox	<1 mg/mL	50 mg/mL	50 mg/mL
S3113	Pyridoxine HCl	41 mg/mL	41 mg/mL	<1 mg/mL
S4245	Sodium ascorbate	40 mg/mL	2 mg/mL	<1 mg/mL

Vitamin Inhibitors (41)
New Vitamin Products

Catalog No.	Information	Product Use Citations	Product Validations
S1469	Calcifediol Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).	Br J Pharmacol, 2017, 174(16):2636-2651	(E) Qualitative representations of zebrafish larvae, showing ISV to be unchanged or slightly reduced in response to 20 μM seocalcitol, maxacalcitol, calcitriol, calcifediol and tacalcitol treatment between 6 hpf and 2 dpf. Scale bar represents 200 μm. (F) Qualitative representation of intact ISV after 10 μM seocalcitol, maxacalcitol, calcitriol, calcifediol and tacalcitol treatment from 2-5 dpf. Scale bar represents 200 μm.
S1468	Alfacalcidol Alfacalcidol is a non-selective VDR activator medication.	Antimicrob Agents Chemother, 2017, AAC.01675-17	Vitamin D analogs induce adenylate kinase release from S. mutans planktonic cells. S. mutans UA159 cultures were grown in TY medium + 1% (w/v) glucose to exponential phase and used to inoculate fresh medium containing ciprofloxacin (positive control), DMSO (negative control), alfacalcidol, calcitriol, or doxercalciferol at 16, 32, and 64 μg/mL for 4h. Cell lysis was detected using the AK assay as described in Materials and Methods. Data is represented as relative luminescence units (RLU) normalized to background (DMSO) and is representative of three replicate cultures performed in triplicate. (* p<0.05; Student’s t-Test; two-tailed).
S5668^New	Chlorindione Chlorindione is an antagonist of vitamin K.
S1921	Phenindione Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
S4144	Amprolium HCl Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake.
S1466	Calcitriol Calcitriol is a nonselective vitamin D receptor activator/agonist(VDRA), exhibiting a 10-fold higher vitamin D receptor (VDR) binding affinity(IC50=0.4 nM) than the selective VDRA paricalcitol.	Endocr Relat Cancer, 2017, 24(4):181-195 Mat Sci Eng C, 2015, 49:14-24 Mol Cell Endocrinol, 2018, 470:1-13	To chemically induce klotho expression, THP-1 cells were treated with Calcitriol. The effects were evaluated on the gene level with real time PCR from 5 to 480 min after treatment and on the protein level with western blot after 48 h and 72 h.
S3114	Vitamin C Vitamin C is a water-soluble vitamin indicated for the prevention and treatment of scurvy.
S1467	Doxercalciferol Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
S5568^New	Tocofersolan Tocofersolan is a synthetic water-soluble version of vitamin E that is used in treatment of vitamin E deficiency.
S5592^New	Vitamin A Vitamin A is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs.
S5386^New	7-Dehydrocholesterol 7-Dehydrocholesterol is the direct precursor of free cholesterol in the cholesterol biosynthetic pathway in mammalian tissues and also a biosynthetic precursor to vitamin D3.
S5203^New	Sulbutiamine Sulbutiamine is a synthetic derivative of thiamine (vitamin B1), belonging to a class of supplements shown to help improve memory, learning capacity, decision-making, concentration, and focus.
S4698^New	Vitamin K1 Vitamin K1, made by plants, is a major type of dietary vitamin K, which is well-known for its role in blood clotting. Vitamin K1 is directly involved in photosynthesis.
S5558^New	D-Pantothenate Sodium D-Pantothenate Sodium, the sodium salt of D-pantothenate, is a derivative of vitamin B5 which is an an essential nutrient and plays important roles in the oxidation of fats and carbohydrates and certain amino acids.
S5474^New	Dibenzoyl Thiamine Dibenzoyl Thiamine, a lipophilic derivative of vitamin B (thiamine), is a kind of food additive that can be rapidly absorbed into the body and converted to thiamine.
S5311^New	Pyridoxal phosphate Pyridoxal phosphate, the active form of vitamin B6, acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.
S5082^New	Vitamin K2 Vitamin K2 is an important fat-soluble vitamin that plays critical roles in protecting heart and brain, and building strong bones. It also plays an important role in cancer protection.
S4987^New	Inositol niacinate
S4994^New	Methylcobalamin Methylcobalamin is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.
S5220^New	D-Pantethine Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine and used as a dietary supplement for lowering blood cholesterol and triglycerides.
S4871^New	Pyridoxal 5-phosphate monohydrate Pyridoxal 5-phosphate monohydrate is an active vitamin B6 metabolite, which is a cofactor in many reactions of amino acid metabolism.
S3980^New	Pyridoxine Pyridoxine, also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase.
S4779^New	Menadiol Diacetate Menadiol Diacetate (Vitamin K4) is a synthetic hydrophilic menadione compound, which is clinically used as hemostasis medicine. It induces caspase-3-related apoptosis pathway via mitochondrial dysfunction and DNA fragmentation.
S4811^New	VitaMin U Vitamin U (Methylmethionine chloride) is a vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract.
S3681^New	Vitamin E Acetate Vitamin E Acetate is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant.
S3130	Biotin (Vitamin B7) Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
S1902	Vitamin B12 Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
S1744	Nicotinic Acid Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.
S4063	cholecalciferol (Vitamin D3) Vitamin D3 is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM.
S1767	Beta Carotene Beta Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A.
S2540	Riboflavin Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
S3211	Thiamine HCl (Vitamin B1) Thiamine or vitamin B1 is a water-soluble vitamin of the B complex, its phosphate derivatives are involved in many cellular processes.
S4503	Calcium D-Panthotenate Calcium D-Panthotenate, also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.
S4126	Retinyl (Vitamin A) Palmitate Vitamin A palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.
S4605	Folic acid Folic acid, a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.
S2297	Ergosterol Ergosterol is a sterol and a biological precursor (a provitamin) to vitamin D2.
S4695	D panthenol Dexpanthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
S4083	Vitamin A Acetate Vitamin A is a group of unsaturated nutritional hydrocarbons, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, among which beta-carotene is the most important.
S3665	Trolox Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.
S3113	Pyridoxine HCl Pyridoxine HCl is a form of vitamin B6.
S4245	Sodium ascorbate Sodium Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.

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