| S3114 |
L-Ascorbic Acid (Vitamin C)
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Vitamin C (L-Ascorbic acid) is a water-soluble vitamin indicated for the prevention and treatment of scurvy.
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Biomaterials, 2025, 314:122873
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Nat Commun, 2024, 15(1):2384
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Research (Wash D C), 2024, 7:0457
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| S1469 |
Calcifediol
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Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol) is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).
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Front Pharmacol, 2023, 14:1135516
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Frontiers in Pharmacology, 2023, 1135516
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FEBS Open Bio, 2023, 1789-1806
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| S1468 |
Alfacalcidol
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Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.
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Sci Adv, 2025, 11(42):eadx8662
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Sci Adv, 2025, 11(10):eads2998
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Front Cell Dev Biol, 2024, 12:1384423
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| S3665 |
Trolox
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Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.
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Nat Commun, 2025, 16(1):6617
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Cell Rep Med, 2025, 6(2):101928
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bioRxiv, 2025, 2025.02.05.636712
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| S6104 |
(±)-α-Tocopherol
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(±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.
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Cell Death Dis, 2025, 16(1):396
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iScience, 2025, 28(5):112363
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Cell Death Differ, 2023, 30(8):1988-2004
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| S3739 |
MC903 (Calcipotriene)
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Calcipotriene (MC903) is a synthetic derivative of calcitriol, a form of vitamin D. It can induce differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and lead to normalization of epidermal growth. Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.Solutions are unstable and should be fresh-prepared.
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Int Immunopharmacol, 2025, 164:115403
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Nutrients, 2024, 16(17)3021
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Arch Dermatol Res, 2024, 316(8):585
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| S6681 |
Paricalcitol
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Paricalcitol is a selective vitamin D receptor agonist. This compound suppresses parathyroid hormone mRNA expression and inhibits parathyroid cell proliferation. It is used to treat secondary hyperparathyroidism in chronic kidney disease.
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Redox Biol, 2025, 80:103518
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Redox Biol, 2024, 70:103062
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Front Pharmacol, 2024, 15:1421577
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| S1467 |
Doxercalciferol
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Doxercalciferol (1α-hydroxyvitamin D2) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.
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FEBS Open Bio, 2023, 13(9):1789-1806
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Int J Mol Sci, 2022, 23(16)9366
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Br J Pharmacol, 2017, 174(16):2636-2651
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| S1744 |
Nicotinic Acid
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Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family.
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Gut Microbes, 2022, 2096989
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Gut Microbes, 2022, 14(1):2096989
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Science Advances, 2021, eabf3895
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| S5082 |
Vitamin K2 (Menaquinone)
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Vitamin K2 (Menaquinone) is an important fat-soluble vitamin that plays critical roles in protecting heart and brain, and building strong bones. It also plays an important role in cancer protection.
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Aging (Albany NY), 2023, 15(24):14764-14790
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Aging (Albany NY), 2023, 14764-14790
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International Journal of Stem Cells, 2021, 119-126
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