Vitamin B12

For research use only.

Catalog No.S1902 Synonyms: Cobalamin, Cyanocobalamin

1 publication

Vitamin B12 Chemical Structure

Molecular Weight(MW): 1355.37

Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 130 In stock
USD 97 In stock
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Selleck's Vitamin B12 has been cited by 1 publication

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Biological Activity

Description Vitamin B12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

Protocol

References

Solubility (25°C)

In vitro DMSO 75 mg/mL (55.33 mM)
Ethanol 10 mg/mL (7.37 mM)
Water 6 mg/mL (4.42 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 1355.37
Formula

C63H88CoN14O14P

CAS No. 68-19-9
Storage powder
in solvent
Synonyms Cobalamin, Cyanocobalamin
Smiles CC(CNC(=O)CCC1(C)C(CC(N)=O)C2N=C1/C(=C/3N=C(/C=C/4N=C(/C(=C/5[N-]C2(C)C(C)(CC(N)=O)C5CCC(N)=O)C)C(C)(CC(N)=O)C4CCC(N)=O)C(C)(C)C3CCC(N)=O)C)O[P]([O-])(=O)OC6C(O)C(OC6CO)[N]7C=NC8=C7C=C(C)C(=C8)C.[Co++

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)
% DMSO % % Tween 80 % ddH2O
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04310059 Not yet recruiting Dietary Supplement: Folic acid|Dietary Supplement: Materna Thalassemia|Folic Acid Deficiency Anemia The University of Hong Kong|Queen Mary Hospital Hong Kong April 1 2020 Not Applicable
NCT04355949 Recruiting Diagnostic Test: Serum vitamin D vitamin B12 folic acid Vitamin D Vitamin B12 and Folic Acid Among Patients With Premature Ejaculation Sohag University February 28 2020 Not Applicable
NCT03853304 Not yet recruiting Other: + Folic acid|Other: + Vitamin B12|Other: DFS Anemia|Folate Deficiency|Vitamin B 12 Deficiency Cornell University|Centers for Disease Control and Prevention|Arogyavaram Medical Centre January 1 2020 Not Applicable
NCT04209634 Recruiting Drug: Pozelimab CD55-deficient Protein-losing Enteropathy|CHAPLE Regeneron Pharmaceuticals January 27 2020 Phase 2|Phase 3
NCT04118699 Recruiting Drug: Rifaximin oral tablet|Drug: Placebo oral tablet Chronic Intestinal Pseudo-obstruction Yokohama City University|ASKA Pharmaceutical Co. Ltd. December 25 2019 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID