Vitamin B12

Synonyms: Cobalamin, Cyanocobalamin

Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

Vitamin B12 Chemical Structure

Vitamin B12 Chemical Structure

CAS No. 68-19-9

Purity & Quality Control

Vitamin B12 Related Products

Biological Activity

Description Vitamin B12 (Cobalamin, Cyanocobalamin) is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06046703 Not yet recruiting
Vitamin B 12 Deficiency|Pregnancy|Nutrient Deficiency|Dietary Exposure
Maastricht University Medical Center
January 1 2025 --
NCT04310059 Not yet recruiting
Thalassemia|Folic Acid Deficiency Anemia
The University of Hong Kong|Queen Mary Hospital Hong Kong
July 1 2024 Not Applicable
NCT06218030 Not yet recruiting
Generalized Anxiety Disorder
Queen''s University
April 2024 Phase 4

Chemical Information & Solubility

Molecular Weight 1355.37 Formula

C63H88CoN14O14P

CAS No. 68-19-9 SDF Download Vitamin B12 SDF
Smiles CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[C-]#N.[Co+3]
Storage (From the date of receipt) Store at 4℃(in the dark)

In vitro
Batch:

DMSO : 100 mg/mL ( (73.78 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 100 mg/mL

Water : 15 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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