Home Metabolism Vitamin chemical Methylcobalamin For research use only.

Methylcobalamin

Synonyms: Mecobalamin, Vancomin, Methycobal, Cobametin

Methylcobalamin (Mecobalamin, Vancomin, Methycobal, Cobametin) is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.

Methylcobalamin Chemical Structure

Methylcobalamin Chemical Structure

CAS: 13422-55-4

Purity & Quality Control

Batch: S499401 DMSO] 100 mg/mL] false] ] ] false] ] ] false Purity: 99.14%
99.14

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Biological Activity

Description Methylcobalamin (Mecobalamin, Vancomin, Methycobal, Cobametin) is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03360435 Completed
Bariatric Surgery Candidate|Vitamin Deficiency|Mineral Deficiency
University of Florida
 December 15 2017 --

Chemical Information & Solubility

Molecular Weight 1344.38 Formula

C63H91CoN13O14P
 
CAS No. 13422-55-4 SDF --
Smiles [CH3-].CC1=CC2=C(C=C1C)N(C=N2)C3C(C(C(O3)CO)OP(=O)([O-])OC(C)CNC(=O)CCC4(C(C5C6(C(C(C(=C(C7=NC(=CC8=NC(=C(C4=N5)C)C(C8(C)C)CCC(=O)N)C(C7(C)CC(=O)N)CCC(=O)N)C)[N-]6)CCC(=O)N)(C)CC(=O)N)C)CC(=O)N)C)O.[Co+3]
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (74.38 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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