Catalog No.S1468 Synonyms: 1-hydroxycholecalciferol

For research use only.

Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.

Alfacalcidol Chemical Structure

CAS No. 41294-56-8

Selleck's Alfacalcidol has been cited by 6 Publications

1 Customer Review

Purity & Quality Control

Choose Selective Vitamin Inhibitors

Biological Activity

Description Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 400.64


CAS No. 41294-56-8
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04085770 Completed Drug: Alfacalcidol 1 MCG Oral Capsule Cardiac Valve Replacement Complication Cairo University April 1 2017 Phase 4
NCT02327091 Completed Drug: alfacalcidol Muscle Weakness Indonesia University April 2012 Phase 3
NCT00469599 Terminated Drug: paricalcitol|Drug: alfacalcidol Secondary Hyperparathyroidism|Chronic Kidney Disease|Vitamin D Deficiency Zealand University Hospital July 2007 Not Applicable

(data from, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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