Name: Retinyl (Vitamin A) Palmitate
Brand: Selleck Chemicals
SKU: S4126
Availability: InStock
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Quality Control

Batch: S412601 Ethanol]5 mg/mL]false]DMSO]3 mg/mL]false]Water]Insoluble]false Purity: 99.11%

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NMR
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Datasheet

99.11

Related Targets	Dehydrogenase HSP Transferase P450 (e.g. CYP17) PDE phosphatase PPAR Carbohydrate Metabolism Mitochondrial Metabolism Casein Kinase
Other Vitamin Inhibitors	Trolox Nicotinic Acid Sodium ascorbate D-Pantethine Amprolium HCl Thiamine pyrophosphate hydrochloride D-Pantothenate Sodium Calcium D-Panthotenate Tocofersolan Ergosterol

Solubility

In vitro
Batch:

Ethanol : 5 mg/mL

DMSO : 3 mg/mL (5.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	524.86	Formula	C₃₆H₆₀O₂	Storage (From the date of receipt)	2 years -20°C liquid
CAS No.	79-81-2	Download SDF		Storage (From the date of receipt)	2 years -20°C liquid
Synonyms	Vitamin A palmitate			SMILES	CCCCCCCCCCCCCCCC(=O)OCC=C(C)C=CC=C(C)C=CC1=C(CCCC1(C)C)C

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

In vitro	The microencapsulation of vitamin A palmitate by gelatin-acacia complex is a promising method for converting an oily vitamin to solid powders for an aid to handling and ease of incorporation in preparations.
In vivo	Vitamin A Palmitate (80 mg/kg daily p.o.) or (800 mg/kg once a week p.o.) dose-dependently decreases the size of papillomas in mice, the daily administration induces a somewhat higher extent of regression than the weekly application if the total doses are compared. Water miscible solutions of Vitamin A Palmitate as well as of Vitamin A acid given by the oral route elicit the same effect on papillomas. Vitamin A Palmitate (A single simultaneous injection of 150 g) enhances cell-mediated immunity to sheep red blood cells(SRBC) as early as 3 days following immunization, and the enhancement persists for at least 3 weeks.
References	[1] https://pubmed.ncbi.nlm.nih.gov/11548863/ [2] https://pubmed.ncbi.nlm.nih.gov/5549257/ [3] https://pubmed.ncbi.nlm.nih.gov/7029099/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-05-15)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07335991	RECRUITING	Vitamin A Deficiency; Idiopathic Scoliosis	Second Affiliated Hospital of Wenzhou Medical University	2025-05-13
NCT05702398	RECRUITING	Skin Cancer; Kidney Transplant Recipients	Rhode Island Hospital	2023-04-01	EARLY_PHASE1
NCT07736768	NOT_YET_RECRUITING	Premature; Preterm Infant Health; Vitamin A Deficiency; Human Milk; Breastfeeding	University of Mississippi Medical Center	2026-08-01
NCT07407101	COMPLETED	Dry Eye Syndrome (DES)	University Hospital, Limoges	2026-04-13
NCT06438562	COMPLETED	Healthy Volunteers; Vitamin A	University of Wisconsin, Madison	2024-07-10
NCT03859687	TERMINATED	Healthy Participants	St. Jude Children's Research Hospital	2019-08-19	PHASE1

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Retinyl (Vitamin A) Palmitate Vitamin chemical

Chemical Structure

Molecular Weight: 524.86