Paricalcitol

For research use only.

Catalog No.S6681 Synonyms: Paracalcin,Zemplar,19-Nor-1-25-OH2D2,19-Nor-colecalciferol

Paricalcitol Chemical Structure

Molecular Weight(MW): 416.64

Paricalcitol is a selective vitamin D receptor agonist. Paricalcitol suppresses parathyroid hormone mRNA expression and inhibits parathyroid cell proliferation. Pariccitol is used to treat secondary hyperparathyroidism in chronic kidney disease.

Size Price Stock Quantity  
USD 187 In stock
USD 727 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

Purity & Quality Control

Choose Selective Vitamin Inhibitors

Biological Activity

Description Paricalcitol is a selective vitamin D receptor agonist. Paricalcitol suppresses parathyroid hormone mRNA expression and inhibits parathyroid cell proliferation. Pariccitol is used to treat secondary hyperparathyroidism in chronic kidney disease.
Targets
vitamin D receptor [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 83 mg/mL (199.21 mM)
Ethanol 13 mg/mL (31.2 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 416.64
Formula

C27H44O3

 

CAS No. 131918-61-1
Storage powder
in solvent
Synonyms Paracalcin,Zemplar,19-Nor-1-25-OH2D2,19-Nor-colecalciferol

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03415854 Recruiting Drug: Paricalcitol (Zemplar) Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma|Pancreatic Adenocarcinoma|Pancreas Metastases|Adenocarcinoma HonorHealth Research Institute|Barts Cancer Institute|Abramson Cancer Center of the University of Pennsylvania|Salk Institute for Biological Studies|Mayo Clinic|Princeton University|Imaging Endpoints|Translational Genomics Research Institute|Stand Up To Cancer|Cancer Research UK|Lustgarten Foundation|University of California San Diego January 31 2018 Phase 2
NCT03331562 Active not recruiting Drug: Pembrolizumab|Drug: paricalcitol|Drug: placebo Pancreatic Cancer|Pancreas Adenocarcinoma|Advanced Pancreatic Cancer|Metastatic Pancreatic Cancer|Metastatic Pancreatic Adenocarcinoma Translational Genomics Research Institute|Stand Up To Cancer|Merck Sharp & Dohme Corp. December 27 2017 Phase 2
NCT02686827 Completed Drug: Paricalcitol|Drug: Placebo (for paricalcitol) Hypersensitivity Laurian Jongejan|Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) October 2015 Phase 2
NCT01457001 Terminated Drug: 25-OH-D vitamin Chronic Renal Failure Italian Society of Nephrology|Società Italiana di Nefrologia November 2012 Phase 3
NCT02372695 Terminated Drug: Paricalcitol Nephropathy Effice Servicios Para la Investigacion S.L.|Jaume Arnó Renal Foundation July 2012 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field
Tags: buy Paricalcitol | Paricalcitol ic50 | Paricalcitol price | Paricalcitol cost | Paricalcitol solubility dmso | Paricalcitol purchase | Paricalcitol manufacturer | Paricalcitol research buy | Paricalcitol order | Paricalcitol mouse | Paricalcitol chemical structure | Paricalcitol mw | Paricalcitol molecular weight | Paricalcitol datasheet | Paricalcitol supplier | Paricalcitol in vitro | Paricalcitol cell line | Paricalcitol concentration | Paricalcitol nmr
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID