Biotin (Vitamin B7)

For research use only.

Catalog No.S3130

1 publication

Biotin (Vitamin B7) Chemical Structure

Molecular Weight(MW): 244.31

Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.

Size Price Stock Quantity  
10mM (1mL in DMSO) USD 130 In stock
USD 97 In stock
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Selleck's Biotin (Vitamin B7) has been cited by 1 publication

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Biological Activity

Description Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
In vitro

Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. In addition, biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays.

Protocol

Solubility (25°C)

In vitro DMSO 49 mg/mL (200.56 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 244.31
Formula

C10H16N2O3S

CAS No. 58-85-5
Storage powder
in solvent
Synonyms N/A
Smiles OC(=O)CCCCC1SCC2NC(=O)NC12

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)
% DMSO % % Tween 80 % ddH2O
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04223232 Active not recruiting Drug: [14C]-MD1003 Healthy Volunteers MedDay Pharmaceuticals SA|Quotient Sciences December 10 2019 Phase 1
NCT04252430 Terminated Drug: MD1003 Healthy Volunteers|Impaired Renal Function MedDay Pharmaceuticals SA|Eurofins Optimed October 9 2019 Phase 1
NCT04252417 Terminated Drug: MD1003 Healthy Volunteers|Hepatic Impairment of Moderate Child Pugh Category MedDay Pharmaceuticals SA|Eurofins Optimed October 11 2019 Phase 1
NCT03364686 Recruiting Biological: Biotin-Labeled Red Blood Cells Healthy Volunteers Gladwin Mark MD|National Heart Lung and Blood Institute (NHLBI)|University of Pittsburgh September 16 2019 Phase 2
NCT03384407 Recruiting Device: Red cell survival in INTERCEPT treated red cells Red Cell Survival in Healthy Volunteers University of Cincinnati|Cerus Corporation|Biomedical Advanced Research and Development Authority January 1 2019 Not Applicable
NCT03746821 Completed Dietary Supplement: Biotin Healthy Volunteers|Biotin Excretion SPD Development Company Limited November 7 2018 Not Applicable

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID