Name: LL37 (Human cathelicidin)
Brand: Selleck Chemicals
SKU: P1201
Rating: 5 (2 reviews)

LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties.

LL37 (Human cathelicidin) Chemical Structure

CAS: 154947-66-7

Selleck's LL37 (Human cathelicidin) has been cited by 2 publications

Purity & Quality Control

Batch: P120101 Water] 50 mg/mL] false] ] ] false] ] ] false Purity: 99.94%

99.94

LL37 (Human cathelicidin) Related Products

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Biological Activity

Description	LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties.

In vitro
In vitro	LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing
Cell Research	Cell lines	HCECs
	Concentrations	1, 2.5, 5, 10 and 20 μg/mL
	Incubation Time	24 h
	Method	Cells were treated with indicated concentrations of drug for 24 h.

References

Chemical Information & Solubility

Molecular Weight	4493.26	Formula	C₂₀₅H₃₄₀N₆₀O₅₃
CAS No.	154947-66-7	SDF	--
Density	95.0~105.0%
Smiles	CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCC(O)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CC(C)C)NNC(CC(C)C)C=O)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCC(O)=O)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(=O)C(=O)C(NNC(C(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)N5CCCC5C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CCC(O)=O)C(=O)C(=O)C(CO)NO)C(C)CC
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 50 mg/mL

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In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

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% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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