For research use only.
Catalog No.S5749 Synonyms: CPZ
CAS No. 50-53-3
Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM.
Selleck's Chlorpromazine has been cited by 17 publications
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|Description||Chlorpromazine (CPZ) is a low-potency typical antipsychotic agent that is used to treat psychotic disorders such as schizophrenia. Chlorpromazine (CPZ) inhibits 5-HT(2A) receptor and dopamine D2 in vitro. Chlorpromazine (CPZ) also inhibits sodium channel and blocks HERG potassium channels with IC50 of 21.6 μM.|
|In vitro||DMSO||64 mg/mL (200.71 mM)|
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|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
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Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT03548714||Completed||Drug: PT150|Other: Beverage||Alcohol Dependence|Alcohol Interaction||Pop Test Oncology LLC|Pharmacotherapies for Alcohol and Substance Abuse Consortium|Congressionally Directed Medical Research Programs|Michael Debakey Veterans Affairs Medical Center|Baylor College of Medicine|University of California San Diego||September 1 2018||Phase 1|
|NCT02943213||Completed||Drug: Chlorpromazine Hydrochloride||Anti-Psychotic|Management of Manifestations of Psychotic Disorders|Treatment of Schizophrenia|Control Nausea and Vomiting|Relief of Restlessness and Apprehension Before Surgery|Acute Intermittent Porphyria|Adjunct in the Treatment of Tetanus|Control Manifestations of the Manic Type of Mani-depressive Illness|Relief of Intractable Hiccups||Cycle Pharmaceuticals Ltd.|Parexel||November 2016||Phase 1|
|NCT02295462||Completed||Other: Person-centered Care|Other: Optimised Treatment||Dementia||Martin-Luther-Universität Halle-Wittenberg|University of Luebeck|University of Witten/Herdecke||December 2014||Not Applicable|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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