Trifluoperazine

For research use only.

Catalog No.S5856 Synonyms: NSC-17474, RP-7623, SKF-5019

5 publications

Trifluoperazine Chemical Structure

CAS No. 117-89-5

Trifluoperazine (NSC-17474, RP-7623, SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.

Selleck's Trifluoperazine has been cited by 5 publications

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Biological Activity

Description Trifluoperazine (NSC-17474, RP-7623, SKF-5019) is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight 407.50
Formula

C21H24F3N3S

CAS No. 117-89-5
Storage powder
in solvent
Synonyms NSC-17474, RP-7623, SKF-5019
Smiles CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Dopamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID