Trifluoperazine

Catalog No.S5856 Synonyms: NSC-17474, RP-7623, SKF-5019

Trifluoperazine Chemical Structure

Molecular Weight(MW): 407.50

Trifluoperazine is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.

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Biological Activity

Description Trifluoperazine is an FDA-approved antipsychotic drug for schizophrenia. It is an inhibitor of calmodulin (CaM) and Dopamine D2 receptor with an IC50 value of 1.2 nM for D2 receptor.

Protocol

References

Solubility (25°C)

Chemical Information

Molecular Weight 407.50
Formula

C21H24F3N3S

CAS No. 117-89-5
Storage powder
in solvent
Synonyms NSC-17474, RP-7623, SKF-5019

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02600741 Completed Schizophrenia Janssen Scientific Affairs LLC July 24 2015 --
NCT02600741 Completed Schizophrenia Janssen Scientific Affairs LLC July 24 2015 --

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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