Sulpiride

For research use only.

Catalog No.S4655 Synonyms: Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil

1 publication

Sulpiride Chemical Structure

CAS No. 15676-16-1

Sulpiride (Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil) is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

Selleck's Sulpiride has been cited by 1 publication

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Biological Activity

Description Sulpiride (Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil) is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.
Targets
D2 receptor [1]
()
In vivo Sulpiride induces a short-term decrease in 5-hydroxyindoles followed by a long-term increase in 5-hydroxyindoles[1].

Protocol

Animal Research:[1]
- Collapse
  • Animal Models: Wistar rats
  • Dosages: 25, 50, or 100 mg/kg
  • Administration: i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 68 mg/mL (199.16 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 341.43
Formula

C15H23N3O4S

CAS No. 15676-16-1
Storage powder
in solvent
Synonyms Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil
Smiles CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01777685 Completed Drug: Sulpiride Healthy Damanhour University January 2013 Not Applicable

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