Genistein

For research use only.

Catalog No.S1342

7 publications

Genistein Chemical Structure

Molecular Weight(MW): 270.24

Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.

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Biological Activity

Description Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM.
Targets
EGFR [1] topo II [1]
In vitro

Genistein is an ATP competitive inhibitor. Genistein inhibits tyrosine phosphorylation in isolated enzyme and receptor preparations and in whole cells including platelets, lymphocytes and a variety of cultured cells. It also inhibits EGF-stimulated phosphorylation in cultured cells as well as inhibition of Topo II (topoisomerase II). Genistein inhibits EGF-stimulated tyrosine phosphorylation in cultured A431 epidermoid carcinoma cells. Inhibition is competitive with ATP and noncompetitive with substrate. [1] Genistein blocks the mitogenic effect mediated by EGF, insulin and thrombin on NIH-3T3 cells.[2] Genistein also acts as an agonist at the GPR30 receptor and binds to PPARγ and estrogen receptors. Genistein also binds to PPARγ, acting as an agonist at this receptor with Ki of 5.7 μM. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
293T cells Ml;CSpVv[3Srb36gZZN{[Xl? NVfMRotyTGm|cHzhZ4Vu\W62IH;mJHs{UF1zN3LleIEu\XO2cnHkbY9tKG[{b32gdoVkd22kaX7hcpQhcHWvYX6gSXJj\XSjIHX4dJJme3OnZDDpckAzQTOWIHPlcIx{NCCLQ{WwQVAvODBzMzFOwG0> M3jOZVE3OjF7NE[z
HeLa cells NE\BNYNHfW6ldHnvckBie3OjeR?= M2jyUGFkfGm4YYTpc44hd2ZiZYP0do9o\W5icnXzdI9ve2ViZXzlcYVvfCCrbjDI[WxiKGOnbHzzJJN1[WKueTD0doFve2[nY4Tl[EB4cXSqIHj1cYFvKEW|dILv[4VvKHKnY3XweI9zKGKndHGsJGVEPTB;MD6wNFQyKM7:TR?= MmrXNVE6ODZ{OEC=
human Ishikawa cells MUHGeY5kfGmxbjDhd5NigQ>? NH\oOlI1KGSjeYO= NYjrWW5KTXO2cn;n[Y5q[yCjY4Tpeol1gSCrbjDoeY1idiCLc3jpb4F4[SClZXzsd{Bie3Onc4Pl[EBieyCrbnT1Z5Rqd25ib3[gZYxs[WyrbnWgdIhwe3CqYYThd4Uh[WO2aY\peJkh[W[2ZYKgOEBl[Xm|IHL5JJBiemFvbnn0do9xcGWwb3ygdoVt\WG|ZTDhd5NigSxiSVO1NF0xNjVzIN88US=> MX:xNlUxOjNyNx?=
human MCF7 cells NET4WYtEgXSxdH;4bYPDqGG|c3H5 NW\rT|A1PDhiaB?= NFfSdopEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBOS0Z5IHPlcIx{KGGodHXyJFQ5KGi{czDifUBOXFRiYYPzZZktKEmFNUC9NUDPxE1? MWOyNFgyOzV{NB?=
NIH3T3 cells NFXTTZhHfW6ldHnvckBie3OjeR?= MYDB[49vcXO2IHHjeIl3cXS7IHH0JGNHXFJvZHXseIFHPTB6IH31eIFvfCCneIDy[ZN{\WRiaX6gUmlJO1R|IHPlcIx{KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJIZwenOtb3zpck1{fGmvdXzheIVlKGO3coLlcpQtKEWFNUC9OE41KM7:TR?= M1Hp[|E5PTl3Nkm2
human HL60 cells MWHGeY5kfGmxbjDhd5NigQ>? Mkf1NlQhcA>? MmjtRY51cWyndXvlcYlkKGGldHn2bZR6KGGpYXnud5QhcHWvYX6gTGw3OCClZXzsd{Bi\nSncjCyOEBpenNiYomgZ4xwdm:pZX7pZ{Bie3OjeTygUGM2OD14LkOg{txO MVixPFE3OzV6OR?=
mouse L1210 cells M3HEcWZ2dmO2aX;uJIF{e2G7 NUPEfJZHOjRiaB?= NFnNbFVCdnSrbHX1b4VucWNiYXP0bZZqfHliYXfhbY5{fCCvb4Xz[UBNOTJzMDDj[YxteyCjZoTldkAzPCCqcoOgZpkh[2yxbn;n[Y5q[yCjc4PhfUwhVEN3ME22MlUh|ryP NH[weWEyQDF4M{W4PS=>
MDCK cells  NI\VdIRHfW6ldHnvckBie3OjeR?= NGfLO|BKdmirYnn0bY9vKG:oIFLDVnAh\XiycnXzd4VlKGmwIF3ER2sh[2WubIOgeZNqdmdiSH;lZ4h{fCB|M{O0NkB{fGGrbnnu[{whUUN3ME22Mlkh|ryP NWfFVWNWOjF|NUS4NFA>
human MOLT3 cells M1fXeWZ2dmO2aX;uJIF{e2G7 MXyyOEBp M4W5UmFvfGmuZYXr[Y1q[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJG1QVFR|IHPlcIx{KGGodHXyJFI1KGi{czDifUBkdG:wb3flcolkKGG|c3H5MEBNSzVyPUeuOUDPxE1? NXHhTlBGOThzNkO1PFk>
ANN-1 cells NILQbodEgXSxdH;4bYPDqGG|c3H5 M16yU2N6fG:2b4jpZ{Bm\m[nY4Sgc44hfi2jYnygeJJidnOob4Lt[YQhdXW{aX7lJGFPVi1zIHPlcIx{NCCLQ{WwQVgh|ryP Ml;tPFIxOTZyMx?=
human MCF7 cells MnmwVJJwdGmoZYLheIlwdiCjc4PhfS=> NWrxSoRsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBme3S{b3flckBz\WOncITvdkBmgHC{ZYPzbY5oKGi3bXHuJG1ETjdiY3XscJMtKEeLNUC9NVAh|ryP NIPqWJcyQThzOE[xNi=>
human Raji cells NYX2bHF[TnWwY4Tpc44h[XO|YYm= NEDvUXMzPCCq M3rpO2FvfGmuZYXr[Y1q[yCjY4Tpeol1gSCjZ3HpcpN1KGi3bXHuJHJicmliY3XscJMh[W[2ZYKgNlQhcHK|IHL5JINtd26xZ3XubYMh[XO|YYmsJGxEPTB;MUOuO{DPxE1? NEXkV2gyQDF4M{W4PS=>
human LoVo cells M1[wcWN6fG:2b4jpZ:Kh[XO|YYm= NUTmeVlOPzJiaB?= NH7Sb3BEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBNd1[xIHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9NVUvQDhizszN M3n6PFIyOTJ7OUe3
K562 cells MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mlr5OUBl[Xm| NULDb4pMT3Kxd4ToJIlvcGmkaYTpc44hd2ZiS{W2NkBk\WyuczDifUBZXFRiYYPzZZkh[W[2ZYKgOUBl[Xm|LDDJR|UxRTF5LkW2JO69VQ>? NEm3VGYyPzRzMUC5Ni=>
RAW 264 cells MX7GeY5kfGmxbjDhd5NigQ>? M4\DPFI1KGh? MnXYTY5pcWKrdHnvckBw\iBzIIXnM41tKEySUz3zeIlufWyjdHXkJHRPTmGucHjhJIFk[3WvdXzheIlwdiCrbjDSRXchOjZ2IHPlcIx{KGGodHXyJFI1KGi{czygTWM2OD1zOD6xJO69VQ>? NWjDe4JqOTd|MkCyOFY>
mouse RAW264.7 cells MU\GeY5kfGmxbjDhd5NigQ>? MnrFNlQhcA>? MULBcpRqcW6obHHtcYF1d3K7IHHjeIl3cXS7IHnuJI1wfXOnIGLBW|I3PC55IHPlcIx{KGG|c3Xzd4VlKGG|IHnubIljcXSrb36gc4YhVFCVLXnu[JVk\WRiVF7GZYxxcGFicILv[JVkfGmxbjD0doVifGWmIEKgbJJ{KGKnZn;y[UBNWFNiY3jhcIxmdmenIH3lZZN2emWmIHHmeIVzKDJ2IHjyd{BjgSCHTFnTRUwhUUN3ME2xPU4yKM7:TR?= NIDTV3YzOTJ6OEeyOy=>
HEK293 cells Mmq3SpVv[3Srb36gZZN{[Xl? M4DOU2FvfGGpb37pd5Qh[WO2aY\peJkh[XRiaIXtZY4hemWlb33ibY5idnRiTGjSZoV1[SCneIDy[ZN{\WRiaX6gTGVMOjl|IHPlcIx{KGK7IHz1Z4ln\XKjc3WgdoVxd3K2ZYKg[4Vv\SCjc4PhfUwhUUN3ME2yNkDPxE1? NHr2TmEyQDN2M{GyOi=>
3T3 cells MXzDfZRwfG:6aXRCpIF{e2G7 NXnNXJhZS3m2b4TvfIlkKGWoZnXjeEBwdiB|VEOgZ4VtdHNuIFnDOVA:OjRizszN MkPDPFIxOTZyMx?=
human MCF7 cells M2HGfmZ2dmO2aX;uJIF{e2G7 MXW2JIg> M1z0TGlvcGmkaYTpc44hd2ZicHjvdoJwdCCnc4Tldk1qdmS3Y3XkJI9zdmm2aHnu[UBl\WOjcnLvfJlt[XOnIHnuJIh2dWGwIF3DSlch[2WubIOgZYZ1\XJiNjDodpMtKEmFNUC9NlYh|ryP NV:yNFlMOTByN{W3OFI>
WiDr human colon cells MWTDfZRwfG:6aXRCpIF{e2G7 MmXlR5l1d3SxeHnjJIVn\mWldDDvckBYcUS{IHj1cYFvKGOxbH;uJINmdGy|LDDJR|UxRTJ5Lkeg{txO M2HPXlgzODF4MEO=
NHEM cells NXq0S2ZHTnWwY4Tpc44h[XO|YYm= MnTFO|IhcA>? NF;rdG5KdmirYnn0bY9vKG:oIH3lcIFvcW5ic4nueIhme2m|IHnuJG5JTU1iY3XscJMh[XO|ZYPz[YQh[XNiW{G0R311cGmxdYLhZ4ltKGmwY3;ydI9z[XSrb36gZYZ1\XJiN{KgbJJ{KGK7IHzpdZVq\CC|Y3nueIltdGG2aX;uJINwfW62aX7nMEBKSzVyPUK5MlIh|ryP NYe5O|JZOTlzM{K5N|Q>
human BxPC3 cell NWfRXY1YWHKxbHnm[ZJifGmxbjDhd5NigQ>? NYe3bI1SSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[WejaX7zeEBpfW2jbjDCfHBEOyClZXzsJIxqdmViYomgUXRVKGG|c3H5MEBKSzVyPUOwJO69VQ>? MXSxOlc5QTd|Nx?=
human LNCAP cells MUfDfZRwfG:6aXRCpIF{e2G7 MUO3NkBp MXHDfZRwfG:6aXPpeJkh[WejaX7zeEBpfW2jbjDMUmNCWCClZXzsd{Bi\nSncjC3NkBpenNiYomgV3JDKGG|c3H5MEBKSzVyPUOwMlY2KM7:TR?= M2HtPFIyOTJ7OUe3
HEK293 cells MVvGeY5kfGmxbjDhd5NigQ>? M1Tjd2FvfGGpb37pd5Qh[WO2aY\peJkh[XRiaIXtZY4hemWlb33ibY5idnRiTGjSZYxxcGFiZYjwdoV{e2WmIHnuJGhGUzJ7MzDj[YxteyCkeTDseYNq\mW{YYPlJJJmeG:{dHXyJIdmdmViYYPzZZktKEmFNUC9N|Eh|ryP MnfMNVg{PDNzMk[=
human HCT116 cells MYLDfZRwfG:6aXRCpIF{e2G7 M2HGc|czKGh? M3mzdWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGhEXDFzNjDj[YxteyCjZoTldkA4OiCqcoOgZpkhVVSWIHHzd4F6NCCLQ{WwQVM1NjlizszN NUTyUIw1OjFzMkm5O|c>
human AGS cells MWDDfZRwfG:6aXRCpIF{e2G7 NVHkOoVyPzJiaB?= M17oXWN6fG:2b4jpZ4l1gSCjZ3HpcpN1KGi3bXHuJGFIWyClZXzsd{Bi\nSncjC3NkBpenNiYomgUXRVKGG|c3H5MEBKSzVyPUSxMlY4KM7:TR?= M2fzPVIyOTJ7OUe3
human PC3 cells MVzQdo9tcW[ncnH0bY9vKGG|c3H5 MVm0PEBp M3OxdGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgZY5lem:pZX6gdoVk\XC2b4Kt[IVncWOrZX70JIh2dWGwIGDDN{Bk\WyuczDpcoN2[mG2ZXSge4l1cCByLk[gcm0hd2ZiZYP0doFlcW:uIHHu[EAxNjdibl2gc4YhfGW|dH;zeIVzd26nIHHmeIVzKDR6IHjyd{BjgSC|dXzmc5Jpd2SjbXnu[UBDKGG|c3H5MEBIUTVyPUSyMlY2QCEQvF2= NWH1[nBjOjF3MUOyO|U>
human A549 cells Moq1R5l1d3SxeHnjxsBie3OjeR?= MWO3NkBp NGrIOGlEgXSxdH;4bYNqfHliYXfhbY5{fCCqdX3hckBCPTR7IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9OFMvODlizszN NGeyT3AzOTF{OUm3Oy=>
human BT20 cell Mnj1VJJwdGmoZYLheIlwdiCjc4PhfS=> MUjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDh[4FqdnO2IHj1cYFvKEKWMkCgZ4VtdCCuaX7lJIJ6KE2WVDDhd5NigSxiSVO1NF01PiEQvF2= MVmxOlc5QTd|Nx?=
human DU145 cells NXvOOItuS3m2b4TvfIlkyqCjc4PhfS=> M3vDSlczKGh? MnHuR5l1d3SxeHnjbZR6KGGpYXnud5QhcHWvYX6gSHUyPDViY3XscJMh[W[2ZYKgO|IhcHK|IHL5JG1VXCCjc4PhfUwhUUN3ME20O{4zQSEQvF2= MVGyNVEzQTl5Nx?=
human U937 cells M4nVXXBzd2yrZnXyZZRqd25iYYPzZZk> NIHa[GU4OiCq M2KxdGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iVUmzO{Bk\WyuczDh[pRmeiB5MjDodpMh[nliV2PUMVgh[XO|YYmsJGlEPTB;NEig{txO NILvfncyPzF3OEC1OC=>
human MOLT3 cells NHjwOHdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4P4NVQ5KGh? MoDzS5Jwf3SqIHnubIljcXSrb36gc4YhcHWvYX6gUW9NXDNiY3XscJMh[W[2ZYKgOFghcHK| M4T6O|E5OTZ|NUi5
human T47D cells MkfLSpVv[3Srb36gZZN{[Xl? MWnFd5Rzd2enbnnjJIFkfGm4aYT5JIlvKGi3bXHuJHQ1P0RiY3XscJMh[XO|ZYPz[YQh[XNiZIL1[{Bt\X[nbDDjZZV{cW6pIIP0bY12dGG2aX;uJI9nKGOnbHygdJJwdGmoZYLheIlwdiCncYXpeoFt\W62IITvJFExKHCPIHXzeJJi\GmxbDDifUBidGGvYYKgZox2\SCjc4PhfS=> MYGxOVc5PzR|Nh?=
human MDA-kb2 cells MYHGeY5kfGmxbjDhd5NigQ>? MXvB[49vcXO2IHHjeIl3cXS7IHH0JIFv\HKxZ3XuJJJm[2WydH;yJIlvKGi3bXHuJG1FSS2tYkKgZ4VtdHNiYYPz[ZN{\WRiYYOgd5RqdXWuYYTpc44hd2ZibIXjbYZmemG|ZTDhZ5Rqfmm2eTDifUBtfWOrZnXyZZNmKHKncH;yeIVzKGenbnWgZZN{[Xl? MVGxPVU6OjJ2NR?=
human MCF7 cells M4PBTGZ2dmO2aX;uJIF{e2G7 NEPkR4cxNjFvMkCg{txO NX21XmRpPCCmYYnz MVHTeIlufWyjdHnvckBw\iCpcn;3eIghcW5iaIXtZY4hVUOINzDj[YxteyCjdDCwMlEhfG9iMkCgeW0h[W[2ZYKgOEBl[Xm|IHL5JG1VXCCjc4PhfS=> NVXGWG5LOjVyN{izNVQ>
HUVE12 cells NGrwe2dHfW6ldHnvckBie3OjeR?= MXvS[ZZmenOjbDDv[kBpgWS{b3flckBx\XKxeHnk[U1qdmS3Y3XkJGxFUCCjY4Tpeol1gSCrbjDoeY1idiCKVW\FNVIh[2WubIO= MmDzNVgxPjh7OEC=
human MCF7 cells NHLSXYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWWyNE0yODBizszN Mn7KOEBl[Xm| M4\LeGdzd3e2aDDpcohq[mm2aX;uJIlvKGi3bXHuJG1ETjdiY3XscJMh[XRiMkCgeI8hOTByIIXNJIFnfGW{IESg[IF6eyCkeTDNWHQh[XO|YYm= MlX5NlUxPzh|MUS=
A431 cells Mm\kSpVv[3Srb36gZZN{[Xl? MUe1NEB1dyB5NTD1US=> M2X0c|M3KGh? NEHPPYlE\WyuIHP5Z4xmKGG{cnXzeEBqdiCqdX3hckBCPDNzIHPlcIx{KGG|c3Xzd4VlKGG|IHTlZ5Jm[XOnIHnuJIFk[3WvdXzheIlwdiCjdDDHNE9IOSCyaHHz[UBifCB3MDD0c{A4PSC3TTDh[pRmeiB|NjDodpMh[nlicILvdIllcXWvIHnv[Ill\SC|dHHpcolv\y2kYYPl[EBndG:5IHP5eI9u\XS{aXOgZY5idHm|aYO= NXfOeWhiOjR2NU[wNFQ>
human SKBR3 cells NYexN4lrTnWwY4Tpc44h[XO|YYm= NUGybVRVPTBidH:gO|UhfU1? NEnmNok{PiCq NWTPTW1{S2WubDDjfYNt\SCjcoLld5QhcW5iaIXtZY4hW0uEUkOgZ4VtdHNiYYPz[ZN{\WRiYYOg[IVkemWjc3WgbY4h[WOldX31cIF1cW:wIHH0JGcxN0dzIIDoZZNmKGG2IEWwJJRwKDd3IIXNJIFnfGW{IEO2JIhzeyCkeTDwdo9xcWSrdX2gbY9lcWSnIIP0ZYlvcW6pLXLhd4VlKG[ub4egZ5l1d22ndILpZ{BidmGueYPpdy=> NUPGOZQxOjR2NU[wNFQ>

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
PPARγ / C/EBPα / αP2 ; 

PubMed: 18384126     


Genistein dose-dependently inhibits adipogenic gene expression. Mouse BMSC cultures were exposed to adipogenic cocktail in the presence of increasing concentrations of genistein. Cells were harvested at day 21, and whole cell proteins were subjected to western blotting analysis. 

p-ERK; 

PubMed: 18384126     


Genistein dose-dependently inhibits the phosphorylation of ERK1/2. Cells were treated as above and harvested at day 5 after 5 min exposure to adipogenic cocktail, and whole cell protein were subjected to western blotting analysis.

Foxo3; 

PubMed: 21639915     


Genistein inhibits EGF-induced translocation of FOXO3. Immunofluorescent staining of experimental monolayers revealed that EGF-induced FOXO3 translocation from the nucleus to the cytosol was inhibited by genistein. This experiment was repeated two times in triplicate.

CIP2A / PARP / Cleaved PARP / Caspase-3 / Cleaved Caspase-3 ; 

PubMed: 27574003     


MCF-7, MCF-7-C3 and T47D cells were treated with genistein (GENI) at indicated concentrations for 48 h. Protein levels of CIP2A and PARP in all three cell lines, and caspase-3, cleaved caspase-3 (C-caspase-3) in MCF-7-C3 and T47D cells were detected with western blot analysis.

p-AKT / AKT ; 

PubMed: 27574003     


Genistein inhibits Akt phosphorylation. MCF-7-C3 and T47D cells were treated with genistein at indicated concentrations for 16 h. Phospho-Akt and Akt were detected with western blotting. *P<0.05.

DNMT-1 / DNMT-3a / DNMT-3b ; 

PubMed: 25931004     


Western blot analysis of the effect of physiological concentrations of genistein (0.5–10 µmol/L) on protein expression of the three DNMT subtypes, DNMT1, DNMT3a and DNMT3b in PCa cells.

18384126 21639915 27574003 25931004
Immunofluorescence
ER-β / pS87 ER-β ; 

PubMed: 25931004     


Cells were treated with DMSO (vehicle) or genistein 1 µmol/L and 10 µmol/L for 4hr. Then, cells were fixed, immunostained with pan ER-β and pS87 antibodies simultaneously and visualized by the confocal microscope. The red fluorescent staining in the first column is for pan ER-β, the green fluorescent staining in the second column is for pS87 and the third column is for both images merged together using image J software.

25931004
In vivo Genistein has chemopreventive effects on breast, prostate, and other endocrine-dependent tumors in adult animals. Genistein in the diet reduced the incidence of poorly differentiated prostatic adenocarcinomas in a dose-dependent manner and down-regulated androgen receptor, estrogen receptor-alpha, progesterone receptor, epidermal growth factor receptor, insulin-like growth factor-I, and extracellular signal-regulated kinase-1 but not estrogen receptor-beta and transforming growth factor-alpha mRNA expressions. Dietary genistein protects against mammary and prostate cancers by regulating specific sex steroid receptors and growth factor signaling pathways.[4] Genistein combined with prostate tumor irradiation causes greater inhibition of primary tumor growth and increases control of spontaneous metastasis to para-aortic lymph nodes, increasing mouse survival. Paradoxically, treatment with genistein alone increases metastasis to lymph nodes. [5]

Protocol

Solubility (25°C)

In vitro DMSO 54 mg/mL (199.82 mM)
Ethanol 2 mg/mL (7.4 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 270.24
Formula

C15H10O5

CAS No. 446-72-0
Storage powder
in solvent
Synonyms N/A
Smiles OC1=CC=C(C=C1)C2=COC3=C(C(=CC(=C3)O)O)C2=O

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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01982578 Recruiting Dietary Supplement: Genistein|Other: Placebo Alzheimer''s Disease Fundación para la Investigación del Hospital Clínico de Valencia|University of Valencia September 1 2017 Not Applicable
NCT02499861 Completed Drug: Decitabine and Genistein Cancer St. Justine''s Hospital July 2015 Phase 1|Phase 2
NCT01628471 Completed Drug: decitabine in combination with genistein Non Small Cell Lung Cancer Uman Pharma|DSM Nutritional Products Inc.|MDEIE Ministry Québec Government|INRS-Institut Armand Frappier Université du Québec November 2012 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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