- mutant EGFR
|Catalog No.||Product Name||Information||Selective / Pan||IC50 / Ki|
Sapitinib (AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell-free assays, more potent than Gefitinib or Lapatinib against NSCLC cell, 100-fold more selective for the ErbB family than MNK1 and Flt. Phase 2.
|Pan||ErbB3, IC50: 4 nM|
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