All New Products Listed Chronologically

Cat.No. Product Name Information Added
S4426 Sacubitril hemicalcium salt Sacubitril (AHU-377) hemicalcium salt, a component of the heart failure medicine LCZ696, is a potent inhibitor of neprilysin (neutral endopeptidase, NEP). Mar 30 2021
S4427 Tenofovir alafenamide hemifumarate Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. Mar 30 2021
S4491 Cetylpyridinium chloride monohydrate Cetylpyridinium chloride (CPC, Hexadecylpyridinium chloride) monohydrate is a broad-spectrum antimicrobial agent that possesses virucidal activity against susceptible and resistant strains of influenza virus by targeting and disrupting the viral envelope. Mar 30 2021
S4493 Sodium nitroprusside Sodium nitroprusside (SNP, Ro 21-2498) is a generically available and rapid-acting intravenous (IV) vasodilator that dilates cerebral vessels and increases internal carotid (ICA) flow. Mar 30 2021
S4492 Dextran Dextran (Dextran 40, Macrodex) is a kind of biocompatible, nontoxic and nonimmunogenic biological substance that has been widely used in drug-delivery systems. Mar 30 2021
S4494 Methionine Methionine (MRX-1024, D-Methionine) is an activitor of GABAA receptor that modulates neuronal activity. Mar 30 2021
S0244 SPI-112 SPI-112 is a not cell permeable inhibitor of Src homology region 2 domain-containing phosphatase 2 (SHP-2, PTPN11) with IC50 of 1 μM in cell-free assay. Mar 30 2021
S0400 KAN0438757 KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3) with IC50 of 0.19 μM and 3.6 μM for PFKFB3 and PFKFB4, respectively. Mar 23 2021
S3589 Bendazol Bendazol (2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan) is a hypotensive drug that enhances NO synthase activity in renal glomeruli and collecting tubules. Bendazol inhibits the progression of form-deprivation myopia (FDM) and suppresses the upregulation of HIF-1α. Mar 22 2021
S3591 Eprinomectin Eprinomectin (EPM, MK-397) is an excellent broad-spectrum endectocide with anthelmintic, insecticidal and miticidal activity. Mar 22 2021
S3592 4-Phenylbutyric acid (4-PBA) 4-Phenylbutyric acid (4-PBA, Benzenebutyric acid) is a histone deacetylase (HDAC) inhibitor and a key epigenetic inducer of anti-HCV hepatic hepcidin. 4-Phenylbutyric acid inhibits LPS-induced inflammation through regulating endoplasmic-reticulum (ER) stress and autophagy in acute lung injury models. Mar 22 2021
S3593 Rhodamine 6G Rhodamine 6G (R6G, Basic Red 1, Rhodamine 590) is a fluorescence tracer that binds to mitochondria, thus reducing the intact mitochondria number and inhibiting mitochondrial metabolic activity. Mar 22 2021
S3597 3-Phenoxybenzoic acid 3-phenoxybenzoic acid (3-PBA), an intermediate metabolite of pyrethroids, is more toxic than its parent compounds and has been detected in milk, soil, and human urine. Mar 22 2021
S4418 Phenol Red sodium salt Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) is used ubiquitously as a pH indicator in tissue culture media ranging from 6.8 (yellow) to 8.2 (red). Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells. Mar 22 2021
S4419 Ensulizole Ensulizole (PBSA), a water soluble sunscreen ingredient, is a sulfonated UV absorber which is characterized by intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation. Mar 22 2021
S4423 Emamectin Benzoate Emamectin Benzoate (EMB, MK-244) activates gamma-amino butyric acid (GABA) transporter. Emamectin Benzoate induces of reactive oxygen species (ROS)-mediated DNA damage and apoptosis. Mar 22 2021
S0310 1-Methyl-7-nitroisatoic anhydride (1M7) 1-methyl-7-nitroisatoic anhydride (1M7) is a commonly applied RNA-SHAPE electrophile for probing 2'-hydroxyl reactivity. Mar 15 2021
S0796 JNJ-632 JNJ-632 is a potent hepatitis B virus (HBV) capsid assembly modulator (CAM) with mean EC50 of 121 nM in HepG2.2.15 cells. Mar 15 2021
S6761 Dalfopristin Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds. Mar 15 2021
S9786 BDTX-189 BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations with Kd of 0.2 nM, 0.76 nM, 13 nM and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. BDTX-189 exhibits anticancer activity. Mar 15 2021
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