HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
A2493 Anti-FLT3 / CD135 Anti-FLT3 / CD135 (IMC-EB10) is a fully human IgG1 monoclonal antibody, targeting the FLT3 tyrosine kinase receptor (CD135) with potential antineoplastic activity. It binds to FLT3 and blocks FLT3 ligand binding to FLT3 and subsequent FLT3 phosphorylation, which may result in the inhibition of FLT3-mediated signal transduction pathways. MW: 145.5 KD. Aug 10 2023
A2494 Anti-FGFR4 / CD334 Anti-FGFR4 / CD334 (U3-1784) is a human monoclonal antibody targeting FGFR4 (human fibroblast growth factor receptor 4), with potential antineoplastic activity. It blocks activation of FGFR4, which inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells. MW: 145.5 KD. Aug 10 2023
A2495 Vofatamab (Anti-FGFR3 / CD333) Vofatamab (Anti-FGFR3 / CD333) is a monoclonal antibody targeting FGFR3. Vofatamab blocks activation of both the wildtype and genetically activated receptor. Vofatamab can be used in the research of metastatic urothelial carcinoma (mUC). MW: 145.5 KD. Aug 10 2023
A2496 Anti-FGFR3 / CD333 Anti-FGFR3 / CD333 (LY3076226) is a human monoclonal antibody targeting FGFR3 (fibroblast growth factor receptor type 3). MW: 145.5 KD. Aug 10 2023
A2497 Bemarituzumab (Anti-FGFR2 / CD332) Bemarituzumab (Anti-FGFR2 / CD332) is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research. MW: 145.24 KD. Aug 10 2023
A2498 Aprutumab (Anti-FGFR2 / CD332) Aprutumab (Anti-FGFR2 / CD332) is a fully human FGFR2 monoclonal antibody, which binds to the FGFR2 isoforms FGFR2-IIIb and FGFR2-IIIc. Aprutumab has the potential for solid tumors research. MW: 78.2 KD. Aug 10 2023
A2499 Burosumab (Anti-FGF23) Burosumab (Anti-FGF23) is a neutralizing antibody, targeting human fibroblast growth factor 23 (FGF23). It can be used for the research of X-linked hypophosphatemia (XLH) and tumor-induced osteomalacia. MW: 145.5 KD. Aug 10 2023
A2500 Rozanolixizumab (Anti-FcRn (FCGRT & B2M)) Rozanolixizumab (Anti-FcRn (FCGRT & B2M)) is a high-affinity humanized monoclonal antibody, targeting human neonatal Fc receptor (FcRn) and is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases. MW: 150 KD. Aug 10 2023
A2501 Lumiliximab (Anti-FceR2 / CD23) Lumiliximab (Anti-FceR2 / CD23) is a monoclonal antibody targeting CD23, that inhibits allergen-induced responses. MW: 145.5 KD. Aug 10 2023
A2502 Emicizumab (Anti-F9 / Factor IX) Emicizumab (Anti-F9 / Factor IX) is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research. MW: 145.5 KD. Aug 10 2023
A2503 Garadacimab (Anti-F12 / Factor XII) Garadacimab (Anti-F12 / Factor XII) is a first-in-class, fully human IgG4 monoclonal antibody targeting activated factor XII (FXIIa). Garadacimab has the potential for hereditary angioedema research. MW: 145.5 KD. Aug 10 2023
A2504 Osocimab (Anti-F11 / Factor XI) Osocimab (Anti-F11 / Factor XI) is an antibody targeting Factor FXI. FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects. MW: 145.5 KD. Aug 10 2023
A2505 Anti-ETBR Anti-ETBR (DEDN6526A) is a humanized immunoglobulin (Ig) G1 monoclonal antibody targeting endothelin B receptor (ETBR). MW: 145.5 KD. Aug 10 2023
A2506 Patritumab (Anti-ERBB3 / HER3) Patritumab (Anti-ERBB3 / HER3) is a neutralizing monoclonal antibody targeting ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. MW: 145.5 KD. Aug 10 2023
A2511 Anti-EphA2 (MEDI-547) Anti-EphA2 (MEDI-547) is a fully human IgG1 monoclonal antibody that is used for targeting EphA2. It selectively binds to cells expressing the EphA2 receptor. MW: 145.12 KD. Aug 10 2023
A2512 Adecatumumab (Anti-EpCAM / TROP1 / CD326) Adecatumumab (Anti-EpCAM / TROP1 / CD326) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is not dependent of K-Ras status. MW: 145.5 KD. Aug 10 2023
A2513 Anti-ENTPD1 / CD39 Anti-ENTPD1 / CD39 (TTX-030) is a fully human monoclonal antibody directed targeting the cell surface receptor CD39. It specifically binds to the CD39 antigen and inhibits both the conversion of adenosine triphosphate (ATP) to adenosine monophosphate (AMP) and the subsequent generation of immunosuppressive extracellular adenosine in the tumor microenvironment (TME). MW: 145.5 KD. Aug 10 2023
A2514 Carotuximab (Anti-Endoglin / CD105) Carotuximab (Anti-Endoglin / CD105) is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions. MW: 145.5 KD. Aug 10 2023
A2515 Parsatuzumab (Anti-EGFL7) Parsatuzumab (Anti-EGFL7) is a humanized monoclonal antibody targeting EGFL7. Parsatuzumab selectively blocks the interaction between EGFL7 and endothelial cells, potentially inhibiting vascular regrowth and reducing vascular endothelial growth factor (VEGF) inhibition. MW: 145.5 KD. Aug 10 2023
A2516 Anti-EFNA4 Anti-EFNA4 (PF-06647263) is a antibody targeting EFNA4. MW: 145.5 KD. Aug 10 2023