All New Products Listed Chronologically

Cat.No. Product Name Information Added
S6911 Nesolicaftor (PTI-428) Nesolicaftor (PTI-428) is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier that increases CFTR expression. Mar 30 2021
S9631 Puromycin aminonucleoside Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response. Mar 30 2021
S7586 PS-48 PS-48 is an allosteric activator of phosphoinositide-dependent protein kinase-1 (PDK1). Mar 30 2021
S5219 Allylestrenol Allylestrenol is an orally active progestagen of the 19-nortestosterone series resembling progesterone. Mar 30 2021
S6584 Amdinocillin Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. Mar 30 2021
S8948 SRX3207 SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively. SRX3207 blocks tumor immunosuppression and increases anti-tumor immunity. Mar 30 2021
S9685 GSK620 GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics. Mar 30 2021
S6463 Sodium tauroglycocholate Sodium tauroglycocholate (STGC, Tauroglycocholic acid sodium salt) is an absorption enhancer of transdermal permeation of drug. Mar 30 2021
S4438 Benzophenone Benzophenone (Diphenyl ketone, Benzoylbenzene) filters out both UVA and UVB rays and is widely used in a great variety of sunscreens and personal care products. Mar 30 2021
S4439 Almitrine mesylate Almitrine mesylate (Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate), a pharmacologically unique respiratory stimulant, acts as an agonist of peripheral chemoreceptors located on the carotid bodies. Almitrine mesylate inhibits the activity of Ca2+-dependent K+ channel by decreasing its open probability with IC50 of 0.22 μM. Mar 30 2021
S4441 Isomalt Isomalt (Palatinitol) is a sugar alcohol used as an excipient in commercially available solid oral dosage forms. Isomalt stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying. Mar 30 2021
S4442 Neotame Neotame is a low-caloric and high-intensity artificial sweetener that reduces the alpha-diversity and altered the beta-diversity of the gut microbiome. Mar 30 2021
S4443 Piperazine adipate Piperazine adipate is a broad spectrum anthelmintic agent that inhibits malate oxidation in Ascaridia galli and Heterakis gallinae. Mar 30 2021
S4444 Hypromellose Hypromellose (Hydroxypropyl Methyl Cellulose, HPMC, Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices. Hypromellose provides the release of a drug in a controlled manner, effectively increasing the duration of release of a drug to prolong its therapeutic effect. Mar 30 2021
S4445 Nonoxynol Nonoxynols (Nonaethylene glycol, Polyethylene glycol nonyl phenyl ether) are nonionic surfactants used as detergents, emulsifiers, wetting agents or defoaming agents. Nonoxynol-9 (N-9), the compound with 9 repeating ethoxy groups, is an over-the-counter, locally acting vaginal spermicide. Mar 30 2021
S4446 Dimercaprol Dimercaprol (Bal, 2,3-Dimercapto-1-propanol, Dithioglycerol) is an acrolein scavenger that inhibits HIV-1 tat activity, viral production, and infectivity in vitro. Mar 30 2021
S4621 Tween-20 Tween-20 (Polysorbates 20) is used in the formulation of biotherapeutic products for both preventing surface adsorption and as a stabilizer against protein aggregation. Mar 30 2021
P1205 GsMTx4 GsMTx4 (Grammostola spatulata mechanotoxin 4, M-theraphotoxin-Gr1a, M-TRTX-Gr1a) is a spider venom peptide that inhibits cationic mechanosensitive channels (MSCs). Mar 30 2021
S4428 Tenofovir alafenamide fumarate Tenofovir alafenamide (TAF, GS-7340) fumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. Mar 30 2021
S4425 Rifamycin S Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Mar 30 2021
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