All New Products Listed Chronologically

Cat.No. Product Name Information Added
E0144 Vernakalant (RSD1235) Hydrochloride

Vernakalant (RSD-1235, MK-6621) is a novel, frequency-dependent Na+ channel and early activating K+ channel blocker that selectively prolongs the atrial refractory period.

Nov 18 2021
E0143 ITE

ITE (2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester) is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) that directly binds to AHR with a Ki of 3 nM.

Nov 18 2021
E0134 L-Albizziin

L-albizziin (L-alpha-amino-beta-ureidopropionic acid) is a potent inhibitor of glutamase. L-albizziin interferes with the utilisation of L-glutamine by the Debaryomyces spp. enzyme probably in a competitive and reversible manner since L-albizziin is also a substrate of the enzyme.

Nov 18 2021
E0148 Linalyl Acetate

Linalyl Acetate (Bergamiol, Bergamol, Linalool acetate) is a naturally occurring phytochemical found in many flowers and spice plants. Linalyl Acetate is a potentially anti-inflammatory agent.

Nov 18 2021
E0141 Bexgliflozin (EGT1442)

Bexgliflozin (EGT1442, EGT-0001442, THR-1442) is a potent and selective SGLT2 inhibitor with an IC50 of 2 nM.

Nov 18 2021
E1013 Bemnifosbuvir Hemisulfate (AT-527)

Bemnifosbuvir Hemisulfate (AT-527, RG-6422, RO 7496998) is a hemi-sulfate salt of AT-511. AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0.47 μM.

Nov 18 2021
E0146 PF-9363 (CTx-648)

PF-9363 (CTx-648) is a potent and selective KAT6A/6B inhibitor with Ki of 0.41 nM and 1.2 nM for KAT6A and KAT6B, respectively. PF-9363 displays potent anti-tumor activity in ER+ breast cancer models.

Nov 18 2021
E0145 LOX-IN-3 Dihydrochloride

LOX-IN-3 Dihydrochloride is an orally active and selective lysyl oxidase (LOX) inhibitor.

Nov 18 2021
S9866 PF-07321332

PF-07321332 is an reversible covalent inhibitor of SARS-CoV-2 main protease (Mpro, also referred to as 3CL protease) with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme.

Nov 15 2021
A2031 Sacituzumab (anti-Trop-2) Sacituzumab (anti-Trop-2) is a fully humanized IgG1 kappa monoclonal antibody that binds Trop-2. Nov 12 2021
A2028 Tiragolumab (anti-TIGIT) Tiragolumab (anti-TIGIT) (RG6058, MTIG7192A) is a humanized IgG1/kappa monoclonal antibody that binds TIGIT to prevent its interaction with its ligand PVR (CD155). Nov 12 2021
A2030 Siltuximab (anti-IL-6) Siltuximab (anti-IL-6) (CNTO 328) is a human-mouse chimeric monoclonal antibody that binds human interleukin-6 (IL-6). Nov 12 2021
A2032 Brodalumab (anti-IL17RA) Brodalumab (anti-IL17RA) (KHK4827, AMG 827) is a recombinant, fully human monoclonal antibody (IgG2) which binds with high affinity to the interleukin (IL) 17 receptor A (IL17R). Nov 12 2021
S3383 RS102895 RS 102895 is a small molecule antagonist of CCR2 with an IC50 of 360 nM. Nov 10 2021
E0110 Baloxavir Baloxavir (Baloxavir acid, S-033447) is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor with an IC50 of 2.5 nM. BXA inhibits viral RNA transcription via selective inhibition of CEN activity. Nov 10 2021
E0053 Evatanepag Evatanepag (CP-533536 free acid) is a potent and selective EP2 receptor agonist with an IC50 of 50 nM for rEP2. Nov 10 2021
S9848 LM11A-31

LM11A-31 is a small molecule p75NTR Ligand that reverses cholinergic neurite dystrophy in alzheimer's diseasemousemodels with mid- to late-stage disease progression.

Nov 10 2021
E0137 GV-58

GV-58 is a novel, selective N-type and P/Q-type Ca2+ channels agonist with IC50s of 7.21 μM and 8.81 μM, respectively.

Nov 10 2021
E0135 CID-1067700

CID-1067700 (ML282) is a pan-GTPase inhibitor with a ki of 12.89 nM for Rab7wt.

Nov 10 2021
E0136 N-Nitrosodiethylamine

N-Nitrosodiethylamine (N-Nitroso-diethylamine, NDEA, diethylnitrosamine, DEN) is DNA reactive after bioactivation and produces tumors in many animal species.

Nov 10 2021
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