HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E4029 Tyramine hydrochloride Tyramine Hydrochloride is a hydrochloride salt of the naturally occurring monoamine derived from the amino acid tyrosine. Tyramine acts as a catecholamine-releasing agent but cannot cross the blood-brain barrier. Sep 14 2023
E4024 Poly-D-lysine hydrobromide Poly-D-lysine hydrobromide is a synthetic polymeric substrate most widely used in neural cell culture. It removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC. Sep 14 2023
E4042 5,5-Dimethyl-1-pyrroline N-oxide 5,5-Dimethyl-1-pyrroline N-oxide (DMPO) is a cell-permeable hydrophilic spin trap agent for superoxide detection. It acts as a neuroprotective agent and incubating lymphocytes with DMPO decreases DNA damage by NiCl2. Sep 14 2023
E4035 Ficoll(R) 400 Ficoll(R) 400 (sucrose-epichlorohydrin copolymer) is a macromolecular crowder that plays a pivotal role in promoting liquid-liquid phase separation (LLPS) of proteins. It is currently utilized in the isolation of serum and peripheral blood mononuclear cells (PBMC) from the whole blood of Parkinson's disease (PD) patients. Sep 14 2023
E4038 Cyclic AMP sodium Cyclic AMP Sodium (Cyclic adenosine monophosphate sodium, Adenosine cyclic 3', 5'-monophosphate sodium) is an adenosine triphosphate derivative and an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. It plays a crucial role as a second messenger in numerous biological processes. Sep 14 2023
S9969 RMC-4630 RMC-4630 (SSE15206) is an inhibitor of microtubule polymerization with a GI50 of 197 nM in HCT116 cells. It can overcome multidrug resistance and cause aberrant mitosis, resulting in G2/M arrest due to incomplete spindle formation in cancer cells. Sep 14 2023
E4039 (S)-(-)-Bay K8644 (S)-(-)-Bay K8644, a conventional racemic mixture of Bay K 8644, is a voltage-sensitive L-type calcium channel agonist. It also activates Ba2+ currents (Iba) with EC50 of 32 nM. Sep 14 2023
E4022 Sodium propionate Sodium propionate (sodium propanoate), a short chain fatty acid, is a white crystalline salt derived from propionic acid with anti-inflammatory properties. Sodium propionate is used as a supplement in transgalactic-oligosaccharides (TOS) medium for the isolation of bifidobacteria and as a supplement in the SCFA (short-chain fatty acid) diet prepared for mice. Sep 13 2023
E4021 3-(Trimethoxysilyl)propyl methacrylate 3-(Trimethoxysilyl)propyl methacrylate (TMPSM) is a reactive monomer and silane coupling agent. It is widely used in thepreparation and fabrication of organic/inorganic hybrid nanomaterials. Sep 13 2023
E4030 N-p-Tosyl-L-phenylalanine chloromethyl ketone N-p-Tosyl-L-phenylalanine chloromethyl ketone (Tosyl phenylalanyl chloromethyl ketone, TPCK) is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis. Sep 11 2023
E4032 5'-Deoxy-5'-(methylthio)adenosine 5'-Deoxy-5'-(methylthio)adenosine (Methylthioadenosine, MTA) is a naturally occurring sulfur-containing nucleoside produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors with Ki of 0.15, 1.13, 13.9, and 0.68 μM for A1, A2A, A2B, and A3, respectively. Sep 11 2023
E4033 4-Nitrophenyl beta-D-glucopyranoside 4-Nitrophenyl beta-D-glucopyranoside is a chromogenic β-D-glucosidase substrate, producing a yellow solution upon cleavage. It is degraded by hydrolysis of enzyme β-glucosidase and quantified by colorimetric detection at 405 nm as a measure of β-glucosidase activity. Sep 11 2023
E4025 Nitrotetrazolium Blue chloride Nitrotetrazolium Blue chloride (Nitro blue tetrazolium chloride, NBT) is a chromogenic substrate used for detecting oxygen metabolites in cells, staining histological tissue sections, and labeling probe-target interactions. Nitrotetrazolium blue chloride is paired with 5-bromo-4-chloro-3-inolyl phosphate (PCIB) to detect alkaline phosphatase activity. Sep 11 2023
P1169 Protamine sulfate Protamine sulfate is a polycationic, highly positively charged protein derived from salmon sperm protein, used to neutralize unfractionated heparin administration (UFH)-induced anticoagulation following cardiovascular surgical procedures. Sep 11 2023
E1425 Nesuparib Nesuparib (JPI-547, NOV140201) is a potential inhibitor of both PARP and tankyrases, with IC50 of 0.005 μM, 0.001 μM, 0.002 μM, and ND for TNKS1, TNKS2, PARP1, and PARP2, respectively. Nesuparib exhibits anti-tumor activity in BRCA-deficient xenograft models. Sep 06 2023
E1502 Deutenzalutamide Deutenzalutamide (HC-1119, MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. It can be used in a treatment of advanced prostate cancer. Sep 04 2023
E4020 1-Oleoyl-rac-glycerol 1-Oleoyl-rac-glycerol (Monoolein) is an endogenous metabolite, also an example of lipid-based nanomaterial. It is commonly utilized to prepare lyotropic cubic liquid crystalline drug delivery systems due to its physicochemical properties. Sep 04 2023
E1429 T1-44 T1-44 is a selective inhibitor of protein arginine methyltransferase 5 (PRMT5). It exhibits anti-tumor activity in pancreatic cancers. Aug 31 2023
E4018 Ammonium sulfate Ammonium sulphate (Mascagnite) is an inorganic sulfate salt used for the purification of enzymes and antibodies. Aug 31 2023
E4017 Calcium chloride dihydrate Calcium chloride dihydrate is a moisture-resistant, cheap, and commonly available calcium salt. It is used as a calcium supplement in the DMEM (Dulbecco's modified Eagle's medium) for use in cell culture studies and to prepare the synthetic brine solution. Aug 30 2023