All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
S0019 JNJ-10229570 JNJ-10229570 (UNII-N9IX402L35) is a potent MC1R and MC5R antagonist. Jan 12 2022
E0078 HBC 530 HBC 530 is an RNA mimic of GFP fluorophore for imaging in live cells and activated by binding to Pepper aptamers. Jan 12 2022
P1211 Apelin-13

Apelin-13 can efficiently antagonize the APJ receptor with EC50 of 0.37 nM and result in suppress the forskolin-stimulated cAMP production.

Jan 12 2022
P1212 (Ala13)-Apelin-13

(Ala13)-Apelin-13 is a potent APJ receptor antagonist and can prevent the apelin-induced reduction in gastric tone and motility.

Jan 12 2022
E0176 Dinotefuran

Dinotefuran (MTI-446), a neonicotinoid, is an effective nAChRs agonist with EC50 of 7.8 μM and shows high insecticidal activity on Da2b2 hybrid nAChRs.

Jan 12 2022
E0181 Zinc acetate dihydrate

Zinc acetate dihydrate (Acetic acid zinc salt dihydrate, Dicarbomethoxyzinc dihydrate) contributes to the antiviral activity of microbicide gel through zinc targeting the reverse transcriptase.

Jan 12 2022
E0183 Magnesium chloride

Magnesium chloride can reduce the activated thromboplastin times.

Jan 12 2022
S9954 SGN-2FF

SGN‐2FF (2-fluorofucose) is an orally bioavailable small‐molecule inhibitor of fucosyltransferase that demonstrated encouraging preclinical antitumor activity in mouse models.

Jan 12 2022
E0346 Ro 20-1724

Ro 20-1724 is a potent inhibitor of PDE IV with Ki value of 3.1 μM and a potent gastric secretagogues.

Jan 12 2022
S9913 PHPS1

PHPS1 (PTP Inhibitor V), a potent and cell-permeable inhibitor, is specific for Shp2 with Ki value of 0.73 μM.

Jan 12 2022
E1030 CCT020312

CCT020312 is a selective PERK (EIF2AK3) activator with an EC50 of 5.1 μM. CCT020312 can be used for the selective activation of EIF2A-mediated translation control.

Jan 12 2022
E0184 2-Mercaptobenzothiazole

2-Mercaptobenzothiazole (Benzothiazole-2-thiol, 2-MBT, Mercapto-2-benzothiazole) is an exceptionally potent inhibitor of banana polyphenoloxidase and can significantly delay the onset of substrate oxidation at concentrations as low as 100 nM.

Jan 12 2022
E0185 Polytetrafluoroethylene

Polytetrafluoroethylene (PTFE) is a biomedical material and has excellent non-stick properties with an exceptionally low coefficient of friction.

Jan 12 2022
E1037 ZZW-115

ZZW-115 is a potent NUPR1 inhibitor with IC50s of 0.42 μM in Hep2G cells and 7.75 μM in SaOS-2 cells. ZZW-115 shows evident antitumor activity through its interaction with NUPR1.

Jan 12 2022
E1099 Ceapin-A7

Ceapin-A7 is a selective and highly potent inhibitor of the ATF6α, which can activate the response to ER stress, with IC50 of 0.59 μM.

Jan 12 2022
S9820 Angiotensin (1-7) Angiotensin (1-7) (Ang-(1-7), Angiotensin fragment 1-7) is a bioactive component of the renin-angiotensin system that is formed endogenously from either Ang I or Ang II. Angiotensin (1-7) is a canine ACE inhibitor with an IC50 of 0.65 μM and inhibits the activity mediated by myostatin through Mas receptor. Jan 12 2022
S8999 Exatecan Mesylate Exatecan Mesylate (DX-8951f) is a water-soluble and non-pro-drug analog of camptothecin and shows significant topoisomerase I inhibition with IC50 of 0.975 μg/ml. Jan 12 2022
S3470 ML198 ML198 is a novel activator of glucocerebrosidase (GCase) and does not inhibit the enzyme's action, but can facilitate its translocation to the lysosome. Dec 30 2021
S8487 AP20187 AP20187 (B/B Homodimerizer) is a chemical inducer of dimerization that activates FKBP-Casp8. Dec 30 2021
P1105 Bulevirtide (Myrcludex B) Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt transport. Dec 30 2021