HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E1599 VT107 VT107 is an enantiomer analogous to VT10 and is a potent inhibitor of pan-TEAD auto-palmitoylation with IC50 of 4.93 nM that blocks TEAD-mediated gene transcription by preventing its association with YAP/TAZ. Oct 31 2023
E1537 MMRi62 MMRi62 is a ferroptosis inducer, targeting MDM2-MDM4 with Kd value of 1.39 μM. It exhibits a P53-independent pro-apoptotic activity against pancreatic ductal adenocarcinoma (PDAC) cells and induce autophagy. Oct 31 2023
E1689 NADPH tetrasodium salt NADPH tetrasodium salt is a ubiquitous coenzyme that acts as an electron donor in many reactions utilizing dehydrogenase and reductase enzymes. It plays a crucial role as a cofactor in the biosynthesis of nucleotides, proteins, and fatty acids. It is essential for neutralizing elevated levels of reactive oxygen species (ROS) generated by increased metabolic activity. Oct 31 2023
S9459 Mecamylamine Hydrochloride Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR(nicotinic acetylcholine receptors) antagonist.It is also a ganglionic blocker and can across the blood-brain barrier. It can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area. Oct 30 2023
E4477 Lumateperone Lumateperone (ITI-007) is an antagonist of 5-HT2A receptor with Ki of 0.54 nM. It has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia. Oct 29 2023
E4587 Sodium alginate Sodium alginate is a sodium salt of alginic acid, can be extracted and purified from the cell walls brown seaweed Laminaria japonica. It has chelating activity and can be used to adsorb heavy metal ions, also has mucosal-protective and hemostatic effects and used in food additives and pharmaceuticals. Oct 29 2023
E1280 Ubrogepant Ubrogepant (MK-1602) is an antagonist of human calcitonin gene-related peptide receptor (CGRP). It potently blocks human α–CGRP–stimulated cAMP responses with an IC50 of 0.081 nM in human CGRP receptor-expressing HEK293 cells. Oct 27 2023
E1495 PF-07220060 (CDK4/6-IN-6) PF-07220060 (CDK4/6-IN-6) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively. Oct 27 2023
S8418 Zeocin (Phleomycin D1, zeomycin) Zeocin (Phleomycin D1, Zeomycin, PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. It causes cell death by binding and cleaving DNA. It shows antiproliferative activities and strong cytotoxicity against HT-29 cells. Oct 27 2023
E4026 Poly(2-hydroxyethyl methacrylate) Poly(2-hydroxyethyl methacrylate) is one of the most important hydrogels in the world of biomaterials. It is the basic component of contact lenses and is also used in the implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agents, etc. Oct 27 2023
E2981 PI4KIIIbeta-IN-10 PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ with an IC50 of 3.6 nM. It also exhibits weak inhibition of PI3KC2γ, PI3Kα, and PI4KIIIα, and <20% inhibition at concentrations up to 20 µM for PI4K2α, PI4K2β, and PI3Kβ. Oct 27 2023
E1517 ZEN-3694 ZEN-3694 is an orally bioavailable bromodomain extraterminal inhibitor (BETi) that leads to down-regulation of expression of AR-signaling in metastatic castrationresistant prostate cancer (mCRPC) models. Oct 24 2023
E4474 Infigratinib Phosphate Infigratinib Phosphate (NVP-BGJ398 phosphate) is the phosphate salt form of infigratinib, an orally bioavailable pan-inhibitor of human fibroblast growth factor receptors (FGFRs) with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively. It also has potential antiangiogenic, antineoplastic and antitumor activities. Oct 24 2023
E1691 Muvalaplin(LY3473329) Muvalaplin(LY3473329) is an orally administered small molecule that inhibits lipoprotein (a) (Lp (a)) formation by blocking the apo(a)-apo B100 interaction. It can be used in research of atherosclerotic disease and aortic stenosis. Oct 23 2023
E4468 Cabotegravir Sodium Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor. It also inhibits organic anion transporter 1/3 (OAT1/OAT3) with IC50 of 0.41 μM and 0.81 μM for OAT3 and OAT1, respectively. Oct 19 2023
E4505 Deoxyribonucleic acid, single stranded from salmon testes Deoxyribonucleic acid, single-stranded from salmon testes, is a ready-to-use solution of a high-quality, sonicated, single-stranded template nonspecific DNA blocking agent that reduces background in nucleic acid hybridization. Oct 19 2023
E4472 Clavulanic acid Clavulanic acid is a naturally occurring, powerful bacterial β-lactamase inhibitor. The beta-lactam ring found in clavulanic acid binds to the active site of beta-lactamase, resulting in enzyme inactivation and enhancing the antibacterial activity of beta-lactam antibiotics like amoxicillin. Oct 19 2023
E1692 BAY 2965501 BAY 2965501 is a potent selective inhibitor of diacylglycerol kinases zeta (DGKζ), restores T-cell cellular DAG level, and induces pERK activation in anergic T-cells via DGK inhibition to assist T-cell mediate tumor cell kill. Oct 19 2023
A2126 Anti-mouse VEGFR-2-InVivo Anti-mouse VEGFR-2-InVivo (Clone: DC101) monoclonal antibody reacts with mouse VEGFR-2 (vascular endothelial growth factor receptor 2) also known as CD309, KDR, and Flk-1 and inhibit VEGFR-2 signaling in vivo. VEGFR-2 plays a key role in vascular development and permeability. Oct 17 2023
A2127 Anti-human CD28-InVivo Anti-human CD28-InVivo (Clone: 9.3) monoclonal antibody reacts with human CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. It stimulate the proliferation of human T cells in vitro. Oct 17 2023