HomeAll New Products Listed Chronologically

All New Products Listed Chronologically

Catalog No. Product Name Information Isotype
E1480 DJ4 DJ4 (EX-A7863) is a potent, selective ATP-competitive inhibitor of ROCK1/2 and MRCKα/β with IC50 of 5/50 nM and 10/100 nM respectively. It blocks stress fiber formation and inhibits migration and invasion of multiple cancer cell line Sep 21 2023
E1477 EP4-IN-1 EP4-IN-1 is a potent prostanoid EP4 receptor inhibitor. It exhibits prospects in tumor immunity and anti-inflammatory analgesia research. Sep 21 2023
E1549 AZD0095 AZD0095 is a selective and orally active Monocarboxylate transporter 4 (MCT4) inhibitor with IC50 of 1.3 nM and effectively inhibits the tumor growth in NCI-H358 xenografts in combination with Cediranib. Sep 21 2023
E2985 Capadenoson Capadenoson (BAY 68-4986) is an orally bioavailable, non-nucleoside partial adenosine A1 receptor agonist that exhibits an anti-ischemic effect. Sep 21 2023
E1433 LY3537982 (KRAS G12C inhibitor 19) LY3537982 (KRAS G12C inhibitor 19) is a highly selective and potent inhibitor of the  KRAS-G12C protein. LY3537982 selectively inhibits the growth of KRAS G12C mutant cells H23 G12C, H358 G12C, and H2122 G12C with IC50s of 1.04 nM, 1.16 nM, and 11.38 nM, respectively. Sep 21 2023
E1578 garsorasib (D-1553 ) Garsorasib (D-1553 ) is a potent and selective oral KRASG12C inhibitor with antitumor activity. It has the potential to treat KRAS G12C-mutated non-small cell lung cancer (NSCLC). Sep 21 2023
E1606 RMC-6291 RMC-6291 is an orally active and covalent inhibitor of KRASG12C(ON). RMC-6291 forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). Sep 21 2023
E1535 icFSP1 icFSP1 is a potent, selective human ferroptosis suppressor protein-1 (hFSP1) inhibitor, promotes ferroptosis and indirectly inhibits FSP1 by inducing condensate formation. Sep 21 2023
E1596 AOH1996 AOH1996 is an orally active small-molecule PCNA inhibitor with potential anti-tumor activity. It enhances the interaction between PCNA and RPB1, the largest subunit of RNA polymerase II. Sep 21 2023
E1413 DEG-77 DEG-77 is a cereblon-dependent degrader of IKZF2 and casein kinase 1α (CK1α). It blocks cell growth and delays leukemia progression in murine and human acute myeloid leukemia (AML) mouse models. Sep 17 2023
E1412 DEG-35 DEG-35 is a cereblon-dependent degrader of IKZF2 and casein kinase 1α (CK1α). It blocks cell growth and delays leukemia progression in murine and human acute myeloid leukemia (AML) mouse models. Sep 17 2023
E4034 Fluorescent Brightener 28 Fluorescent Brightener 28 (Tinopal UNPA-GX) is a viability stain used for identification of structure chitin and fungi. It is also used as a fluorescent brightening agent for cellulose and polyamide fabrics, paper and in detergents and soaps. Sep 17 2023
E1602 Lotiglipron Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. It reduces glucose and body weight, and has the potential to be used in Type 2 diabetes mellitus (T2DM) research. Sep 17 2023
E4029 Tyramine hydrochloride Tyramine Hydrochloride is a hydrochloride salt of the naturally occurring monoamine derived from the amino acid tyrosine. Tyramine acts as a catecholamine-releasing agent but cannot cross the blood-brain barrier. Sep 14 2023
E4024 Poly-D-lysine hydrobromide Poly-D-lysine hydrobromide is a synthetic polymeric substrate most widely used in neural cell culture. It removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC. Sep 14 2023
E4042 5,5-Dimethyl-1-pyrroline N-oxide 5,5-Dimethyl-1-pyrroline N-oxide (DMPO) is a cell-permeable hydrophilic spin trap agent for superoxide detection. It acts as a neuroprotective agent and incubating lymphocytes with DMPO decreases DNA damage by NiCl2. Sep 14 2023
E4035 Ficoll(R) 400 Ficoll(R) 400 (sucrose-epichlorohydrin copolymer) is a macromolecular crowder that plays a pivotal role in promoting liquid-liquid phase separation (LLPS) of proteins. It is currently utilized in the isolation of serum and peripheral blood mononuclear cells (PBMC) from the whole blood of Parkinson's disease (PD) patients. Sep 14 2023
E4038 Cyclic AMP sodium Cyclic AMP Sodium (Cyclic adenosine monophosphate sodium, Adenosine cyclic 3', 5'-monophosphate sodium) is an adenosine triphosphate derivative and an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. It plays a crucial role as a second messenger in numerous biological processes. Sep 14 2023
S9969 RMC-4630 RMC-4630 (SSE15206) is an inhibitor of microtubule polymerization with a GI50 of 197 nM in HCT116 cells. It can overcome multidrug resistance and cause aberrant mitosis, resulting in G2/M arrest due to incomplete spindle formation in cancer cells. Sep 14 2023
E4039 (S)-(-)-Bay K8644 (S)-(-)-Bay K8644, a conventional racemic mixture of Bay K 8644, is a voltage-sensitive L-type calcium channel agonist. It also activates Ba2+ currents (Iba) with EC50 of 32 nM. Sep 14 2023