Catalog No.S7977 Synonyms: BBI608
Molecular Weight(MW): 240.21
Napabucasin is an orally available Stat3 and cancer cell stemness inhibitor.
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|Description||Napabucasin is an orally available Stat3 and cancer cell stemness inhibitor.|
Napabucasin downregulates stemness gene expression driven by Stat3 and cancer stemness properties, and effectively inhibits self-renewal of stemness-high cancer cells with IC50 ranged from 0.291~1.19 μM, on inhibition on normal stem cells.